scholarly journals Quantitative estimation of IL-6 in serum/plasma samples using a rapid and cost-effective fiber optic dip-probe

2010 ◽  
Author(s):  
Chun-Wei Wang ◽  
Upender Manne ◽  
Vishnu B. Reddy ◽  
Rakesh Kapoor
Keyword(s):  
Fiber Optic ◽  
Quantitative Estimation ◽  
Cost Effective ◽  
Plasma Samples

Plasma enhanced label-free immunoassay for alpha-fetoprotein based on a U-bend fiber-optic LSPR biosensor

RSC Advances ◽  
2015 ◽  
Vol 5 (31) ◽  
pp. 23990-23998 ◽  
Author(s):  
Gaoling Liang ◽  
Zhongjun Zhao ◽  
Yin Wei ◽  
Kunping Liu ◽  
Wenqian Hou ◽  
...  
Keyword(s):  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Localized Surface Plasmon Resonance ◽  
Fiber Optic ◽  
Cost Effective ◽  
Alpha Fetoprotein ◽  
Localized Surface Plasmon ◽  
Label Free

A simple, label-free and cost-effective localized surface plasmon resonance (LSPR) immunosensing method was developed for detection of alpha-fetoprotein (AFP).

scholarly journals Luffa cylindrica Immobilized with Aspergillus terreus QMS-1: an Efficient and Cost-Effective Strategy for the Removal of Congo Red using Stirred Tank Reactor

2020 ◽  
Vol 69 (2) ◽  
pp. 193-203
Author(s):  
QANDEEL LARAIB ◽  
MARYAM SHAFIQUE ◽  
NUSRAT JABEEN ◽  
SEHAR AFSHAN NAZ ◽  
HAFIZ RUB NAWAZ ◽  
...  
Keyword(s):  
Congo Red ◽  
Textile Industry ◽  
Aspergillus Terreus ◽  
Quantitative Estimation ◽  
Oxygen Demand ◽  
Cost Effective ◽  
Stirred Tank ◽  
Luffa Cylindrica ◽  
Stirred Tank Bioreactor ◽  
Efficient System

Microbial populations within the rhizosphere have been considered as prosperous repositories with respect to bioremediation aptitude. Among various environmental contaminants, effluent from textile industries holds a huge amount of noxious colored materials having high chemical oxygen demand concentrations causing ecological disturbances. The study was aimed to explore the promising mycobiome of rhizospheric soil for the degradation of azo dyes to develop an efficient system for the exclusion of toxic recalcitrants. An effluent sample from the textile industry and soil samples from the rhizospheric region of Musa acuminata and Azadirachta indica were screened for indigenous fungi to decolorize Congo red, a carcinogenic diazo dye, particularly known for its health hazards to the community. To develop a bio-treatment process, Aspergillus terreus QMS-1 was immobilized on pieces of Luffa cylindrica and exploited in stirred tank bioreactor under aerobic and optimized environment. Quantitative estimation of Congo red decolorization was carried out using UV-Visible spectrophotometer. The effects of fungal immobilization and biosorption on the native structure of Luffa cylindrica were evaluated using a scanning electron microscope. A. terreus QMS-1 can remove (92%) of the dye at 100 ppm within 24 h in the presence of 1% glucose and 1% ammonium sulphate at pH 5.0. The operation of the bioreactor in a continuous flow for 12 h with 100 ppm of Congo red dye in simulated textile effluent resulted in 97% decolorization. The stirred tank bioreactor was found to be a dynamic, well maintained, no sludge producing approach for the treatment of textile effluents by A. terreus QMS-1 of the significant potential for decolorization of Congo red.

Detecting and Correcting Pipeline Leaks Before They Become a Big Problem

2015 ◽  
Vol 49 (1) ◽  
pp. 31-46 ◽  
Author(s):  
Ron Cramer ◽  
David Shaw ◽  
Robert Tulalian ◽  
Pabs Angelo ◽  
Maarten van Stuijvenberg
Keyword(s):  
Acoustic Wave ◽  
Real Time ◽  
Fiber Optic ◽  
Cost Effective ◽  
Leak Detection ◽  
Rate Of Change ◽  
Fiber Optic Cable ◽  
History Of ◽  
Distributed Acoustic Sensing ◽  
Critical Lines

AbstractTimely pipeline leak detection is a significant business issue in view of a long history of catastrophic incidents and growing intolerance for such events. It is vital to flag containment loss and location quickly, credibly, and reliably for all green or brown field critical lines in order to shut down the line safely and isolate the leak. Pipelines are designed to transport hydrocarbons safely; however, leaks have severe safety, economic, environmental, and reputational effects. This paper will highlight robust, reliable, and cost-effective methods, most of which leverage real-time instrumentation, telecommunications, SCADA, DCS, and associated online leak detection applications. The purpose of this paper will be to review the underlying leak detection business issues, catalogue the functional challenges, and describe experiences with available technologies. Internal and external techniques will be described, including basic rate of change of flow and pressure, compensated mass balance, statistical, real-time transient modeling, acoustic wave sensing, fiber optic cable (distributed temperature, distributed acoustic sensing), and subsea hydrophones. The paper will also describe related credibility, deployment, organizational, and maintenance issues with an emphasis on upstream applications. The scope will include leak detection for pipelines conveying various flowing fluids—gas, liquid, and multiphase flow. Pipeline environments will include subsea and onshore. Advantages, disadvantages, and experiences with these techniques will be described and analyzed.

scholarly journals Errata: Development of combination tapered fiber-optic biosensor dip probe for quantitative estimation of interleukin-6 in serum samples

2011 ◽  
Vol 16 (1) ◽  
pp. 019801 ◽  
Author(s):  
Chun Wei Wang ◽  
Upender Manne ◽  
Vishnu B. Reddy ◽  
Denise K. Oelschlager ◽  
Venkat R. Katkoori ◽  
...  
Keyword(s):  
Interleukin 6 ◽  
Fiber Optic ◽  
Quantitative Estimation ◽  
Serum Samples ◽  
Tapered Fiber

scholarly journals Rapid Identification of Plasma DNA Samples with Increased ctDNA Levels by a Modified FAST-SeqS Approach

2015 ◽  
Vol 61 (6) ◽  
pp. 838-849 ◽  
Author(s):  
Jelena Belic ◽  
Marina Koch ◽  
Peter Ulz ◽  
Martina Auer ◽  
Teresa Gerhalter ◽  
...  
Keyword(s):  
Screening Method ◽  
Cost Effective ◽  
Maternal Blood ◽  
Circulating Tumor Dna ◽  
Rapid Identification ◽  
Plasma Samples ◽  
Plasma Dna ◽  
Aneuploidy Screening ◽  
Z Scores ◽  
Tumor Genome

Abstract BACKGROUND Recent progress in the analysis of cell-free DNA fragments [cell-free circulating tumor DNA (ctDNA)] now allows monitoring of tumor genomes by noninvasive means. However, previous studies with plasma DNA from patients with cancer demonstrated highly variable allele frequencies of ctDNA. The comprehensive analysis of tumor genomes is greatly facilitated when plasma DNA has increased amounts of ctDNA. Therefore, a fast and cost-effective prescreening method to identify such plasma samples without previous knowledge about alterations in the respective tumor genome could assist in the selection of samples suitable for further extensive qualitative analysis. METHODS We adapted the recently described Fast Aneuploidy Screening Test-Sequencing System (FAST-SeqS) method, which was originally established as a simple, effective, noninvasive screening method for fetal aneuploidy from maternal blood. RESULTS We show that our modified FAST-SeqS method (mFAST-SeqS) can be used as a prescreening tool for an estimation of ctDNA percentage. With a combined evaluation of genome-wide and chromosome arm–specific z-scores from dilution series with cell line DNA and by comparisons of plasma-Seq profiles with data from mFAST-SeqS, we established a detection limit of ≥10% mutant alleles. Plasma samples with an mFAST-SeqS z-score >5 showed results that were highly concordant with those of copy number profiles obtained from our previously described plasma-Seq approach. CONCLUSIONS Advantages of this approach include the speed and cost-effectiveness of the assay and that no prior knowledge about the genetic composition of tumor samples is necessary to identify plasma DNA samples with >10% ctDNA content.

scholarly journals A highly compact and cost-effective 2-beamsuper-resolution structured illuminationmicroscope based on all-fiber optic components

2021 ◽  
Author(s):  
Thomas Huser ◽  
Jakub Pospisil ◽  
Karel Fliegel ◽  
Miloš Klíma ◽  
Gerd Wiebusch
Keyword(s):  
Fiber Optic ◽  
Cost Effective

An Innovative Immunoanalysis Strategy towards Sensitive Recognition of PSA Biomarker in Human Plasma Samples Using Flexible and Portable Paper Based Biosensor: A New Platform towards POC Detection of Cancer Biomarkers Using Integration of Pen-on Paper Technology with Immunoassays Methods

2021 ◽  
Vol 1 (1) ◽  
pp. 6-6
Author(s):  
Fatemeh Farshchi ◽  
Arezoo Saadati ◽  
Houman Kholafazad kordasht ◽  
Mohammad Hasanzadeh
Keyword(s):  
Prostate Cancer ◽  
Human Plasma ◽  
Specific Antigen ◽  
Cost Effective ◽  
Plasma Samples ◽  
Label Free ◽  
Free Paper ◽  
Detection Range ◽  
Efficient Treatment ◽  
Human Plasma Samples

Background: The prostate-specific antigen (PSA) is one of the best markers for detecting prostate cancer. Rapid and real time recognition of PSA biomarker could be helpful in the early diagnosis and efficient treatment of prostate cancer. One of the usual methods to identify this biomarker is ELISA, which has a picomolar detection range but requires specialized personnel and also this technique is time-consuming and expensive. Methods: Cost-effective POC devices are great solutions because they are very cost-effective, sensitive and simple, do not require expert operators and have a high response time in a short time. With that in mind, in this work, a novel and simple label-free paper-based electrochemical immunosensor were designed by using conductive Ag-ink and designed directly by pen on paper technique on the surface of photographic paper, which is a suitable substrate for antibody immobilization, for rapid detection of PSA. Results: Based on the obtained results, under the optimum conditions, the synthesized Ag ink has a great substrate for antibody (Ab) and antigen (Ag) immobilization. The linear range was from 0.001 to 30 μg/L and the obtained low limite of quantification (LLOQ) was 0.001μg/L. This immunosensor also tested in human plasma samples, which had good analytical power. Conclusion: The proposed paper-based immunoassay could be a hopefully new and cheap tool for the diagnosis of other biomarkers.

Hybrid Solar Lighting System Cost and Performance Analysis

2001 ◽  
Author(s):  
Michael T. Panich ◽  
Eric E. Carlson ◽  
Michael F. Jerla
Keyword(s):  
Solar Radiation ◽  
Fiber Optic ◽  
Tracking System ◽  
Cost Effective ◽  
Photovoltaic Cell ◽  
Commercial Building ◽  
Full Spectrum ◽  
Electric System ◽  
Solar Lighting ◽  
And Performance

Abstract This paper reports on the methodology and results of a preliminary analysis of a hybrid solar lighting concept that has the potential to provide cost-effective topside daylighting to the core areas of commercial buildings of all types. The presented hybrid lighting concept also includes a “full spectrum” dish-type concentrating solar collector. This collector uses both the incident visible and infrared solar radiation to provide both daylighting and electric power. The incident solar radiation is separated using cold mirror technology. Visible light is sent to a fiber optic bundle for routing to integrated fiber optic/fluorescent luminaires within the building. Separated infrared solar radiation is focused on a photovoltaic cell and converted to electricity. The electricity produced provides self-powering of the collector solar tracking system and the excess electricity produced is sent into the grid-connected commercial building electric system. The paper presents the potential for performance increases/cost reductions in the technology and the current and future cost competitiveness of this promising solar technology.

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