Enhanced PNA detection sensitivity based on polymer-cladded porous silicon waveguide

2010 ◽  
Author(s):  
Yang Jiao ◽  
Sharon M. Weiss
Keyword(s):  
Porous Silicon ◽  
Detection Sensitivity ◽  
Silicon Waveguide

Porous silicon waveguide with integrated grating coupler for DNA sensing

2009 ◽  
Author(s):  
Xing Wei ◽  
Christopher Kang ◽  
Guoguang Rong ◽  
Scott T. Retterer ◽  
Sharon M. Weiss
Keyword(s):  
Porous Silicon ◽  
Grating Coupler ◽  
Dna Sensing ◽  
Silicon Waveguide

Optical Detection of Polyacrylamide Swelling Behavior in a Porous Silicon Sensor

2008 ◽  
Vol 1133 ◽  
Author(s):  
Lisa M. Bonanno ◽  
Lisa A. DeLouise
Keyword(s):  
Refractive Index ◽  
Porous Silicon ◽  
Optical Response ◽  
Crosslinking Density ◽  
Detection Sensitivity ◽  
Cross Linking ◽  
Volume Sensitivity ◽  
Swelling Capacity ◽  
Silicon Sensor

Abstract This work proves that a 1-D porous silicon (PSi) sensor is capable of monitoring the optical changes in a polyacrylamide (PAAm) hydrogel that correlate with swelling capacity. The PSi device was impregnated with PAAm hydrogel with varying crosslinking density and total solids. The optical response of the PSi sensor was utilized to distinguish the changes in refractive index of hydrogels with varying cross-linking densities. Refractive index values calculated by the composite hydrogel-PSi sensor response agree well (≤1% difference) with values measured using a bench-top refractometer. This work serves to build a foundation for creating a composite biochemical-responsive hydrogel-PSi sensor in which competitive binding of a target analyte would cause a reduction in hydrogel cross-linking density. Long-term goals of this work are to exploit the volume sensitivity of a PSi sensor and leverage the added optical response of the responsive hydrogel to increase target detection sensitivity in an affinity based biosensor.

A novel biosensor with enhanced sensitivity based on grating coupled double-layered porous silicon waveguide

2012 ◽  
Vol 8 (3) ◽  
pp. 179-181
Author(s):  
Xiao-yi Lü ◽  
Jia-qing Mo ◽  
Hong-yan Zhang ◽  
Fu-ru Zhong ◽  
Zhen-hong Jia
Keyword(s):  
Porous Silicon ◽  
Silicon Waveguide ◽  
Enhanced Sensitivity

Nanoscale porous silicon waveguide for label-free DNA sensing

2008 ◽  
Vol 23 (10) ◽  
pp. 1572-1576 ◽  
Author(s):  
Guoguang Rong ◽  
Ali Najmaie ◽  
John E. Sipe ◽  
Sharon M. Weiss
Keyword(s):  
Porous Silicon ◽  
Label Free ◽  
Dna Sensing ◽  
Silicon Waveguide ◽  
Free Dna

scholarly journals Guided mode biosensor based on grating coupled porous silicon waveguide

2011 ◽  
Vol 19 (12) ◽  
pp. 11330 ◽  
Author(s):  
Xing Wei ◽  
Sharon M. Weiss
Keyword(s):  
Porous Silicon ◽  
Silicon Waveguide ◽  
Guided Mode
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