Study on dynamics of photon migration in human breast based on three-dimensional Monte Carlo modeling

2010 ◽  
Author(s):  
Ching-Cheng Chuang ◽  
Chung-Ming Chen ◽  
Chia-Yen Lee ◽  
Jui-che Tsai ◽  
Chih-Wei Lu ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Three Dimensional ◽  
Photon Migration ◽  
Human Breast ◽  
Monte Carlo Modeling

MCVM: MONTE CARLO MODELING OF PHOTON MIGRATION IN VOXELIZED MEDIA

2010 ◽  
Vol 03 (02) ◽  
pp. 91-102 ◽  
Author(s):  
TING LI ◽  
HUI GONG ◽  
QINGMING LUO
Keyword(s):  
Monte Carlo ◽  
Refractive Index ◽  
High Precision ◽  
Heterogeneous Media ◽  
Homogeneous Medium ◽  
Software Tool ◽  
Light Transport ◽  
Photon Migration ◽  
Monte Carlo Code ◽  
Monte Carlo Modeling

The Monte Carlo code MCML (Monte Carlo modeling of light transport in multi-layered tissue) has been the gold standard for simulations of light transport in multi-layer tissue, but it is ineffective in the presence of three-dimensional (3D) heterogeneity. New techniques have been attempted to resolve this problem, such as MCLS, which is derived from MCML, and tMCimg, which draws upon image datasets. Nevertheless, these approaches are insufficient because of their low precision or simplistic modeling. We report on the development of a novel model for photon migration in voxelized media (MCVM) with 3D heterogeneity. Voxel crossing detection and refractive-index-unmatched boundaries were considered to improve the precision and eliminate dependence on refractive-index-matched tissue. Using a semi-infinite homogeneous medium, steady-state and time-resolved simulations of MCVM agreed well with MCML, with high precision (~100%) for the total diffuse reflectance and total fractional absorption compared to those of tMCimg (< 70%). Based on a refractive-index-matched heterogeneous skin model, the results of MCVM were found to coincide with those of MCLS. Finally, MCVM was applied to a two-layered sphere with multi-inclusions, which is an example of a 3D heterogeneous media with refractive-index-unmatched boundaries. MCVM provided a reliable model for simulation of photon migration in voxelized 3D heterogeneous media, and it was developed to be a flexible and simple software tool that delivers high-precision results.

Monte Carlo modeling of time-resolved near-infrared transillumination of human breast tissue

1994 ◽  
Author(s):  
Oliver Schuetz ◽  
Hans-Erich Reinfelder ◽  
Klaus W. Klingenbeck-Regn ◽  
Hartmut Bartelt
Keyword(s):  
Monte Carlo ◽  
Breast Tissue ◽  
Near Infrared ◽  
Human Breast ◽  
Human Breast Tissue ◽  
Monte Carlo Modeling ◽  
Time Resolved

scholarly journals Three-dimensional Monte Carlo modeling of laser-tissue interaction

1999 ◽  
Author(s):  
Beop-Min Kim ◽  
Nicholas A. Gentile ◽  
Kenneth B. Trauner ◽  
Richard A. London
Keyword(s):  
Monte Carlo ◽  
Three Dimensional ◽  
Monte Carlo Modeling ◽  
Tissue Interaction ◽  
Laser Tissue Interaction
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