Multispectral imaging techniques observing the dynamic changes in the hemoglobin concentrations as diagnostic tool for diseased tissues

2010 ◽  
Author(s):  
John H. G. M. Klaessens ◽  
Herke Jan Noordmands ◽  
Rowland de Roode ◽  
Rudolf M. Verdaasdonk
Author(s):  
Olga V. Polschikova ◽  
Alexander Machikhin ◽  
Vladislav Batshev ◽  
Alina Ramazanova ◽  
Artyom Belov ◽  
...  

2021 ◽  
Vol 2021 (1) ◽  
pp. 107-112
Author(s):  
Andrea J. Loewenwarter ◽  
Margaret L. Misch ◽  
Kristin Jacobsen ◽  
Mills Kelly ◽  
Michael B. Toth

Historic properties face challenges preserving and maintaining their physical heritage, as well as digitally sharing and accessing their history in a virtual environment. They are now utilizing new advanced imaging methods to research their cultural heritage artifacts. Recent advanced imaging in historic Civil War-era houses demonstrated the integration of imaging techniques and data to support conservation of these structures and research into their history and contents. New technical systems, including the latest narrowband multispectral imaging systems and higher resolution cameras, raise major challenges in not only the integration of new technologies, but also the ability to store, manage and access large amounts of data. Integration, preservation, access and collaboration with the image data from this program requires implementation of standardized digitization and data archiving practices.


2021 ◽  
Vol 42 (Supplement_1) ◽  
Author(s):  
L Schrutka ◽  
P Anner ◽  
B Seirer ◽  
R Rettl ◽  
F Duca ◽  
...  

Abstract Background The diagnosis of cardiac amyloidosis (CA) requires advanced imaging techniques. Typical surface ECG patterns have been described, but their diagnostic value is limited. Purpose The aim of this study was to perform a comprehensive electrophysiological characterization in CA patients and to develop a robust, easy-to-use diagnostic tool. Methods First, we applied electrocardiographic imaging (ECGI) to generate detailed electroanatomical maps in CA patients and controls. Then, a machine learning approach was used to generate a surface ECG-based diagnostic algorithm from the complex dataset. Results Areas of low voltage were localized in the basal inferior regions of both ventricles and the remaining right ventricular segments in CA. The earliest epicardial breakthrough of myocardial activation was visualized in the right ventricle. Potential maps showed an accelerated and diffuse propagation pattern. We correlated the results from ECGI with 12-lead ECG recordings. Ventricular activation correlated best with R-peak timing in leads V1 to V3. Epicardial voltage showed a strong positive correlation with R-peak amplitude in inferior leads II, III, aVF. Ten blinded cardiologists were then asked to identify CA patients by analyzing 12-lead ECGs before and after training for the defined ECG patterns. Training resulted in significant improvements in the detection rate of CA with an AUC of 0.69 before and 0.97 after training (Figure). Conclusion Using a machine learning approach, a robust ECG-based tool was developed to detect CA from detailed electroanatomical mapping of CA patients. The developed tool proved to be a simple and reliable diagnostic tool to suspect CA without the aid of advanced imaging modalities. FUNDunding Acknowledgement Type of funding sources: None.


2014 ◽  
Vol 51 (3) ◽  
pp. 58-66 ◽  
Author(s):  
A. Silapetere ◽  
J. Spigulis ◽  
I. Saknite

Abstract Skin chromophore phantoms are widely used for better understanding of the light interaction with tissue and for calibration of skin diagnostic imaging techniques. In this work, different phantoms were examined and compared in order to find biologically equivalent substances that are the most promising for this purpose. For mimicking the skin medium and layered structure, a fibrin matrix with epidermal and dermal cell inclusion was used. Synthesized bilirubin, red blood cells and nigrosin were taken as absorbers. For spectral analysis of the developed phantoms a computer-aided multispectral imaging system Nuance 2.4 (Cambridge Research & Instrumentation, Inc., USA) was used. In this study, skin phantoms were created using such substances as bilirubin, melanin, haemoglobin and nigrosin


2006 ◽  
Vol 19 (3) ◽  
pp. 279-288 ◽  
Author(s):  
Joachim Böttcher ◽  
Alexander Pfeil ◽  
Anders Rosholm ◽  
Max-Ludwig Schäfer ◽  
Ansgar Malich ◽  
...  

2016 ◽  
Vol 5 (8) ◽  
pp. 360-378 ◽  
Author(s):  
Jeffrey E. Thatcher ◽  
John J. Squiers ◽  
Stephen C. Kanick ◽  
Darlene R. King ◽  
Yang Lu ◽  
...  

2005 ◽  
Author(s):  
Qiongshui Wu ◽  
Yaojun Hu ◽  
Hengyu Ke ◽  
Libo Zeng ◽  
Yi Ding

Heritage ◽  
2021 ◽  
Vol 4 (3) ◽  
pp. 2320-2336
Author(s):  
Antonella Privitera ◽  
Maria Francesca Alberghina ◽  
Elèna Privitera ◽  
Salvatore Schiavone

This work presents the results of the in situ, non-invasive diagnostic investigations performed on the canvas oil painting depicting Madonna and Child, venerated as ‘Maria Santissima delle Grazie’ by the local religious community. The work of art (72 cm × 175 cm) is located on the high altar of the main Church in Mirabella Imbáccari, near Catania (Sicily, Italy). The painter is anonymous, and the supposed dating is the late eighteenth century. Although the painting has never been studied before, it has been attributed to a Sicilian workshop in the literature, raising the doubts of the art historian who conducted this study and who hypothesized a Neapolitan manufacture. Furthermore, due to the good conservation state detected by a macroscopic examination, doubts also arose about dating. To shed light on these aspects, a technical-scientific examination proved necessary. Multispectral imaging techniques (IR Reflectography, UV-induced visible Fluorescence, X-ray) are carried out for the study of the execution technique, the identification of underlying remakes, sketch drawing and the evaluation of the conservation conditions. XRF spectrometry analysis is performed for the identification of the chemical elements constituting the pigments (inorganic chromophores). The diagnostic results allowed this research to confirm the dating suggested by the historical-stylistic knowledge and to highlight new technical peculiarities supporting the attribution to a Neapolitan workshop.


Sign in / Sign up

Export Citation Format

Share Document