Simultaneous SLO/OCT imaging of the human retina in vivo with high speed axial eye motion correction

2008 ◽  
Author(s):  
Michael Pircher ◽  
Erich Götzinger ◽  
Bernhard Baumann ◽  
Harald Sattmann ◽  
Christoph K. Hitzenberger
2007 ◽  
Vol 15 (25) ◽  
pp. 16922 ◽  
Author(s):  
Michael Pircher ◽  
Bernhard Baumann ◽  
Erich Götzinger ◽  
Harald Sattmann ◽  
Christoph K. Hitzenberger

Author(s):  
MICHAEL PIRCHER ◽  
ROBERT J. ZAWADZKI ◽  
JULIA EVANS ◽  
JOHN S. WERNER ◽  
CHRISTOPH K. HITZENBERGER

2018 ◽  
Vol 9 (2) ◽  
pp. 591 ◽  
Author(s):  
Kari V. Vienola ◽  
Mathi Damodaran ◽  
Boy Braaf ◽  
Koenraad A. Vermeer ◽  
Johannes F. de Boer

2006 ◽  
Vol 14 (26) ◽  
pp. 12902 ◽  
Author(s):  
H. Lim ◽  
M. Mujat ◽  
C. Kerbage ◽  
E. C. W. Lee ◽  
Y. Chen ◽  
...  

2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Jiang Lan Fan ◽  
Jose A. Rivera ◽  
Wei Sun ◽  
John Peterson ◽  
Henry Haeberle ◽  
...  

AbstractUnderstanding the structure and function of vasculature in the brain requires us to monitor distributed hemodynamics at high spatial and temporal resolution in three-dimensional (3D) volumes in vivo. Currently, a volumetric vasculature imaging method with sub-capillary spatial resolution and blood flow-resolving speed is lacking. Here, using two-photon laser scanning microscopy (TPLSM) with an axially extended Bessel focus, we capture volumetric hemodynamics in the awake mouse brain at a spatiotemporal resolution sufficient for measuring capillary size and blood flow. With Bessel TPLSM, the fluorescence signal of a vessel becomes proportional to its size, which enables convenient intensity-based analysis of vessel dilation and constriction dynamics in large volumes. We observe entrainment of vasodilation and vasoconstriction with pupil diameter and measure 3D blood flow at 99 volumes/second. Demonstrating high-throughput monitoring of hemodynamics in the awake brain, we expect Bessel TPLSM to make broad impacts on neurovasculature research.


2013 ◽  
Vol 25 (17) ◽  
pp. 1741-1743 ◽  
Author(s):  
Jianbing Xu ◽  
Haiyan Ou ◽  
Xie Wang ◽  
P. C. Chui ◽  
Hwa Yaw Tam ◽  
...  
Keyword(s):  

Sign in / Sign up

Export Citation Format

Share Document