In vitro cardiac catheter navigation via augmented reality surgical guidance

Author(s):  
Cristian A. Linte ◽  
John Moore ◽  
Andrew Wiles ◽  
Jennifer Lo ◽  
Chris Wedlake ◽  
...  
2008 ◽  
Vol 19 (4) ◽  
pp. 279-284 ◽  
Author(s):  
Axel Schlitt ◽  
Hans J. Rupprecht ◽  
Iris Reindl ◽  
Sebastian Schubert ◽  
Baerbel Hauroeder ◽  
...  

2018 ◽  
Vol 5 (5) ◽  
pp. 189-193 ◽  
Author(s):  
Houssam El‐Hariri ◽  
Prashant Pandey ◽  
Antony J. Hodgson ◽  
Rafeef Garbi

2008 ◽  
Vol 100 (10) ◽  
pp. 693-698 ◽  
Author(s):  
Michael Buerke ◽  
Sebastian Schubert ◽  
Iris Reindl ◽  
Thomas Michel ◽  
Baerbel Hauroeder ◽  
...  

SummaryBivalirudin, a direct thrombin inhibitor binds specifically and reversibly to both fibrin-bound and unbound thrombin. Bivalirudin is approved for use as an anticoagulant in patients undergoing percutaneous coronary intervention. The OASIS-5 trial presented a significant increase in cardiac catheter thrombosis for the pentasaccharid fondaparinux compared to enoxaparin. Catheter thrombosis has never been reported in any trial using bivalirudin. Our study compared the development of catheter thrombosis for bivalirudin, enoxaparin, and unfractionated heparin in a controlled in-vitro environment. Ten healthy male volunteers were pretreated with aspirin 500 mg 2 hours before venesection of 50 ml of blood. The seven groups of anticoagulant combinations tested were:UFH, UFH + eptifibatide, enoxaparin, enoxaparin + eptifibatide, bivalirudin bolus, bivalirudin + eptifibatide, bivalirudin bolus + continuous infusion. The blood/anticoagulant mix continuously circulated through a cardiac guiding catheter for 60 minutes or until the catheter became blocked with thrombus. Thrombus development was assessed by weighing each catheter before and after the procedure. Electron microscopy was used to quantify the degree of erythrocyte, platelet and fibrin deposition. Following anticoagulation with bolus dose bivalirudin, the catheter was invariably occluded with thrombus after 33 minutes of circulation. However, a continuous infusion of Bivalirudin prevented the development of occlusive catheter thrombosis. In the bolus bivalirudin group the mean thrombus weight was significantly greater than in all other groups (p-value < 0.01 in all analyses). Bivalirudin given as a bolus was not sufficient to prevent cardiac catheter thrombosis in our in-vitro study. However, a continuous infusion of bivalirudin had similar anti-thrombotic efficacy compared to other treatment strategies.


2013 ◽  
Vol 34 (suppl 1) ◽  
pp. P4851-P4851
Author(s):  
A. Kaeberich ◽  
C. Cremer ◽  
I. Reindl ◽  
C. Domenger ◽  
J. Kaiser ◽  
...  

2011 ◽  
Vol 35 (11) ◽  
pp. 1127-1131 ◽  
Author(s):  
Jun Woo Park ◽  
Jaesoon Choi ◽  
Yongdoo Park ◽  
Kyung Sun

2020 ◽  
Vol 185 (Supplement_1) ◽  
pp. 513-520
Author(s):  
Edgar Rojas-Muñoz ◽  
Maria Eugenia Cabrera ◽  
Chengyuan Lin ◽  
Natalia Sánchez-Tamayo ◽  
Dan Andersen ◽  
...  

ABSTRACT Introduction Point-of-injury (POI) care requires immediate specialized assistance but delays and expertise lapses can lead to complications. In such scenarios, telementoring can benefit health practitioners by transmitting guidance from remote specialists. However, current telementoring systems are not appropriate for POI care. This article clinically evaluates our System for Telementoring with Augmented Reality (STAR), a novel telementoring system based on an augmented reality head-mounted display. The system is portable, self-contained, and displays virtual surgical guidance onto the operating field. These capabilities can facilitate telementoring in POI scenarios while mitigating limitations of conventional telementoring systems. Methods Twenty participants performed leg fasciotomies on cadaveric specimens under either one of two experimental conditions: telementoring using STAR; or without telementoring but reviewing the procedure beforehand. An expert surgeon evaluated the participants’ performance in terms of completion time, number of errors, and procedure-related scores. Additional metrics included a self-reported confidence score and postexperiment questionnaires. Results STAR effectively delivered surgical guidance to nonspecialist health practitioners: participants using STAR performed fewer errors and obtained higher procedure-related scores. Conclusions This work validates STAR as a viable surgical telementoring platform, which could be further explored to aid in scenarios where life-saving care must be delivered in a prehospital setting.


2009 ◽  
Vol 181 (4S) ◽  
pp. 275-275
Author(s):  
Dogu Teber ◽  
Esref Oguz Guven ◽  
Matthias Baumhauer ◽  
Tobias Simpfendörfer ◽  
Jens Rassweiler

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