Simultaneous measurements of optical coherence tomography and fluorescence spectroscopy based on double clad fiber

2009 ◽  
Author(s):  
Seon Young Ryu ◽  
Hae Young Choi ◽  
Jihoon Na ◽  
Eun Seo Choi ◽  
Byeong Ha Lee
Keyword(s):  
Optical Coherence Tomography ◽  
Fluorescence Spectroscopy ◽  
Optical Coherence ◽  
Simultaneous Measurements

scholarly journals Multimodal analysis of pearls and pearl treatments by using optical coherence tomography and fluorescence spectroscopy

2011 ◽  
Vol 19 (7) ◽  
pp. 6420 ◽  
Author(s):  
Myeong Jin Ju ◽  
Sang Jin Lee ◽  
Yuri Kim ◽  
Jun Geun Shin ◽  
Hae Yeon Kim ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Fluorescence Spectroscopy ◽  
Optical Coherence ◽  
Multimodal Analysis

Combined swept-source optical coherence tomography and fluorescence spectroscopy system

2010 ◽  
Author(s):  
Seon Young Ryu ◽  
Myeong Jin Ju ◽  
Kwan Seob Park ◽  
Joo Beom Eom ◽  
Byeong Ha Lee
Keyword(s):  
Optical Coherence Tomography ◽  
Fluorescence Spectroscopy ◽  
Optical Coherence ◽  
Swept Source ◽  
Spectroscopy System

LIGHT-INDUCED FLUORESCENCE SPECTROSCOPY AND OPTICAL COHERENCE TOMOGRAPHY OF BASAL CELL CARCINOMA

2009 ◽  
Vol 02 (03) ◽  
pp. 261-268 ◽  
Author(s):  
EKATERINA BORISOVA ◽  
ELFRIDA CARSTEA ◽  
LUMINITA CRISTESCU ◽  
ELMIRA PAVLOVA ◽  
NIKOLAY HADJIOLOV ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Skin Cancer ◽  
Basal Cell Carcinoma ◽  
Fluorescence Spectroscopy ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Normal Skin ◽  
Biological Tissues ◽  
Skin Lesions ◽  
Optical Coherence

Many up-to-date optical techniques have been developed and applied recently in clinical practice for obtaining qualitatively and quantitatively new data from the investigated lesions. Due to their high sensitivity in detection of small changes, these techniques are widely used for detection of early changes in biological tissues. Light-induced fluorescence spectroscopy (LIFS) is one of the most promising techniques for early detection of cutaneous neoplasia. Increasing number of recent publications have suggested that optical coherence tomography (OCT) also has potential for non-invasive diagnosis of skin cancer. This recent work is a part of clinical trial procedure for introduction of LIFS technique into the common medical practice in National Oncological Medical Center in Bulgaria for diagnosis of non-melanoma skin cancer. We focus our attention here on basal cell carcinoma lesions and their specific features revealed by LIFS and OCT analysis. In this paper we prove the efficiency of using the combined LIFS-OCT method in skin lesions studies by integrating the complimentary qualities of each particular technique. For LIFS measurements several excitation sources, each emitting at 365, 385 and 405 nm maxima are applied. An associated microspectrometer detects in vivo the fluorescence signals from human skin. The main spectral features of the lesions and normal skin are discussed and their possible origins are indicated. OCT images are used to evaluate the lesion thickness, structure and severity stage, when possible. The obtained results could be used to develop a more complete picture of optical properties of these widely spread skin disorders. At the same time, our studies show that the combined LIFS-OCT method could be introduced in clinical algorithms for early tumor detection and differentiation between normal/benign/malignant skin lesions.

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