Dynamic analysis of laser ablation of biological tissue using a real-time OCT

2009 ◽  
Author(s):  
Makoto Ohnishi ◽  
Daisuke Takada ◽  
Masato Ohmi ◽  
Masamitsu Haruna
Keyword(s):  
Laser Ablation ◽  
Dynamic Analysis ◽  
Real Time ◽  
Biological Tissue

Real-time OCT imaging of laser ablation of biological tissue

2010 ◽  
Author(s):  
Masato Ohmi ◽  
Makoto Ohnishi ◽  
Daisuke Takada ◽  
Masamitsu Haruna
Keyword(s):  
Laser Ablation ◽  
Real Time ◽  
Biological Tissue ◽  
Oct Imaging

scholarly journals Magnetic Resonance Thermometry-Guided Stereotactic Laser Ablation of Cavernous Malformations in Drug-Resistant Epilepsy: Imaging and Clinical Results

2015 ◽  
Vol 12 (1) ◽  
pp. 39-48 ◽  
Author(s):  
D Jay McCracken ◽  
Jon T Willie ◽  
Brad A Fernald ◽  
Amit M Saindane ◽  
Daniel L Drane ◽  
...  
Keyword(s):  
Laser Ablation ◽  
Magnetic Resonance ◽  
Minimally Invasive ◽  
Real Time ◽  
Refractory Epilepsy ◽  
Acute Hemorrhage ◽  
Cavernous Malformations ◽  
Remote Imaging ◽  
Medically Refractory Epilepsy

Abstract BACKGROUND Surgery is indicated for cerebral cavernous malformations (CCMs) that cause medically refractory epilepsy. Real-time magnetic resonance thermography (MRT)-guided stereotactic laser ablation (SLA) is a minimally invasive approach to treating focal brain lesions. SLA of CCM has not previously been described. OBJECTIVE To describe MRT-guided SLA, a novel approach to treating CCM-related epilepsy, with respect to feasibility, safety, imaging, and seizure control in 5 consecutive patients. METHODS Five patients with medically refractory epilepsy undergoing standard presurgical evaluation were found to have corresponding lesions fulfilling imaging characteristics of CCM and were prospectively enrolled. Each underwent stereotactic placement of a saline-cooled cannula containing an optical fiber to deliver 980-nm diode laser energy via twist drill craniostomy. MR anatomic imaging was used to evaluate targeting before ablation. MR imaging provided evaluation of targeting and near real-time feedback regarding the extent of tissue thermocoagulation. Patients maintained seizure diaries, and remote imaging (6-21 months postablation) was obtained in all patients. RESULTS Imaging revealed no evidence of acute hemorrhage following fiber placement within presumed CCM. MRT during treatment and immediate postprocedure imaging confirmed the desired extent of ablation. We identified no adverse events or neurological deficits. Four of 5 (80%) patients achieved freedom from disabling seizures after SLA alone (Engel class 1 outcome), with follow-up ranging 12 to 28 months. Reimaging of all subjects (6-21 months) indicated lesion diminution with surrounding liquefactive necrosis, consistent with the surgical goal of extended lesionotomy. CONCLUSION Minimally invasive MRT-guided SLA of epileptogenic CCM is a potentially safe and effective alternative to open resection. Additional experience and longer follow-up are needed.

scholarly journals Real-time measurement of diffusion exchange rate in biological tissue

2020 ◽  
Vol 317 ◽  
pp. 106782
Author(s):  
Nathan H. Williamson ◽  
Rea Ravin ◽  
Teddy X. Cai ◽  
Dan Benjamini ◽  
Melanie Falgairolle ◽  
...  
Keyword(s):  
Exchange Rate ◽  
Real Time ◽  
Biological Tissue ◽  
Time Measurement ◽  
Real Time Measurement

Pressure generation during inertially confined laser ablation of biological tissue

1993 ◽  
Author(s):  
I. Itzkan ◽  
D. Albagli ◽  
B. J. Banish ◽  
M. Dark ◽  
C. von Rosenberg ◽  
...  
Keyword(s):  
Laser Ablation ◽  
Biological Tissue
Sign in / Sign up

Export Citation Format

Share Document