Design and fabrication of an omnidirectional reflector as ultra-sensitive biochemical sensing platform

2008 ◽  
Author(s):  
Jian Gao ◽  
Agus Widjaja ◽  
Mengshu Pan ◽  
Andrew Sarangan ◽  
Qiwen Zhan
Keyword(s):  
Biochemical Sensing ◽  
Sensing Platform

scholarly journals Refractometric Sensitivity Enhancement of Weakly Tilted Fiber Bragg Grating Integrated with Black Phosphorus

Nanomaterials ◽  
2020 ◽  
Vol 10 (7) ◽  
pp. 1423
Author(s):  
Zhao Zhang ◽  
Kun Liu ◽  
Junfeng Jiang ◽  
Tianhua Xu ◽  
Shuang Wang ◽  
...  
Keyword(s):  
Fiber Bragg Grating ◽  
Deposition Process ◽  
Sensitivity Enhancement ◽  
Black Phosphorus ◽  
Bragg Grating ◽  
Layer By Layer ◽  
Biochemical Sensing ◽  
Sensing Platform ◽  
Potential Applications ◽  
Cladding Mode

The sensitivity enhancement of the weakly tilted fiber Bragg grating (WTFBG) integrated with black phosphorus (BP) was investigated via numerical simulations and experimental demonstrations. BP nanosheets were deposited twice on the cylindrical WTFBG surface using the in situ layer-by-layer (i-LbL) deposition technique. The resonance intensity of the deepest cladding mode located around 1552 nm of WTFBG had a 9.2 dB decrease after the BP deposition process. This allows for the application of the intensity-modulated refractive index (RI) sensor. The sensing platform was implemented on the use of the BP integrated with WTFBG (BP-WTFBG). The refractometric sensing was achieved with the sensitivity enhancement of the resonance intensity modulation of the deepest cladding mode for the BP-WTFBG. The sensitivities were 137.6 dB/RIU and 75.6 dB/RIU in the RI region of 1.33–1.35 and 1.35–1.38, respectively. This platform shows great potential applications for biochemical sensing because of its highly sensitive RI sensing ability around the biochemical sensing window.

Real-time Analysis of Electrolytes in Sweat Through a Wearable Sensing Platform

Proceedings ◽  
2019 ◽  
Vol 15 (1) ◽  
pp. 14
Author(s):  
Pirovano ◽  
Shinde ◽  
White ◽  
Wallace ◽  
McCaul ◽  
...  
Keyword(s):  
Real Time ◽  
Point Of Care ◽  
Electrolyte Composition ◽  
Sensor Data ◽  
Ion Selective Electrodes ◽  
Time Analysis ◽  
Capillary Action ◽  
Real Time Analysis ◽  
Biochemical Sensing ◽  
Sensing Platform

The field of biochemical sensing is evolving from the use of bulky apparatuses to the development of miniaturized systems allowing personal sensing and point of care analysis. We report a wearable platform capable of measuring the concentration of multiple electrolytes in sweat (Na+, K+, Cl−). The platform accesses sweat emerging through the skin, drawing it across solid-state ion-selective electrodes by capillary action. The electrolyte composition is monitored in real time by potentiometry. The sensor data is digitised and transmitted via Bluetooth to a mobile phone or laptop. The platform has been employed in on-body trials during controlled exercise.

Optical Sensors for Detection of Amino Acids

2018 ◽  
Vol 25 (19) ◽  
pp. 2272-2290 ◽  
Author(s):  
Aafrin M. Pettiwala ◽  
Prabhat K. Singh
Keyword(s):  
Amino Acids ◽  
Optical Sensors ◽  
Supramolecular Assemblies ◽  
Significant Activity ◽  
Physiological Level ◽  
Biological Scaffolds ◽  
Detection Systems ◽  
Sensing Platform ◽  
Neurological Conditions ◽  
Detailed Search

Background: Amino acids are crucially involved in a myriad of biological processes. Any aberrant changes in physiological level of amino acids often manifest in common metabolic disorders, serious neurological conditions and cardiovascular diseases. Thus, devising methods for detection of trace amounts of amino acids becomes highly elemental to their efficient clinical diagnosis. Recently, the domain of developing optical sensors for detection of amino acids has witnessed significant activity which is the focus of the current review article. Methods: We undertook a detailed search of the peer-reviewed literature that primarily deals with optical sensors for amino acids and focuses on the use of different type of materials as a sensing platform. Results: Ninety-five papers have been included in the review, majority of which deal with optical sensors. We attempt to systematically classify these contributions based on the applications of various chemical and biological scaffolds such as polymers, supramolecular assemblies, nanoparticles, DNA, heparin etc for the sensing of amino acids. This review identifies that supramolecular assemblies and nanomaterial continue to be commonly used platforms to devise sensors for amino acids followed by surfactant assemblies. Conclusion: The broad implications of amino acids in human health and diagnosis have stirred a lot of interest to develop optimized optical detection systems for amino acids in recent years, using different materials based on chemical and biological scaffolds. We have also attempted to highlight the merits and demerits of some of the noteworthy sensor systems to instigate further efforts for constructing amino acids sensor based on unconventional concepts.

Selective Sensing Platform Utilizing Graphitized Multi-Walled Carbon Nanotubes for Monitoring of Ondansetron and Paracetamol

2020 ◽  
Vol 16 ◽  
Author(s):  
Biljana Nigović ◽  
Iva Šimunić ◽  
Ana Mornar
Keyword(s):  
Carbon Nanotubes ◽  
Cation Exchange ◽  
Supporting Electrolyte ◽  
Polymer Concentration ◽  
Fixed Dose ◽  
Sensing Platform ◽  
Multi Walled Carbon Nanotubes ◽  
Electroanalytical Method ◽  
Walled Carbon Nanotubes

Background: Ondansetron and paracetamol are often co-administrated to prevent and treat nausea and vomiting caused by anaesthesia and to control of postoperative pain. In addition, ondansetron is used as the first-line antiemetic in paracetamol overdose. Therefore, selective and sensitive method for their simultaneous analysis is of a great importance. The electroanalytical methods are highly sensitive and offer many possibilities for new sensor platform design. However, at present, no electroanalytical method for simultaneous determination of these drugs has been proposed. Objective: The aim of this study was to develop a novel nanosensor for selective monitoring of ondansetron and paracetamol in pharmaceutical and biological samples without expensive and time-consuming pretreatments. Methods: The graphitized multi-walled carbon nanotubes embedded in a cation exchange polymer matrix was selected, among various surface functionalizations evaluated, to design novel sensor. Based on its excellent sensing performance, the first electroanalytical method was developed for rapid concurrent determination of investigated drugs. Results: The scanning electron microscopy study showed interlinked nanoporous network structure and highly enlarged active surface. The developed sensor facilitated electron transfer in the oxidation of both drugs and tremendously enhanced the adsorption capacity for ondasetron, thus exhibiting significant increase of drug responses and sensitivity. To obtain much sensitive response of investigated drugs the effect of pH values of supporting electrolyte, dispersed nanomaterial amount, the cation exchange polymer concentration, drop-casting volume of nanocomposite suspension, accumulation potential and deposition time on the peak current was evaluated. The developed electroanalytical method was validated and practical utility of the proposed nanosensor was tested. Conclusion: The developed sensor is promising sensing platform with a fast response time for analysis of ondansetron and paracetamol at very different concentration levels found in their fixed-dose combination and human serum sample after recommended daily doses showing its potential usage in pharmaceutical quality control and clinical research.

Colorimetric Dye-Loaded Nanofiber Yarn: Eye-Readable and Weavable Gas Sensing Platform

ACS Nano ◽  
2020 ◽  
Vol 14 (12) ◽  
pp. 16907-16918
Author(s):  
Dong-Ha Kim ◽  
Jun-Hwe Cha ◽  
Jee Young Lim ◽  
Jaehyeong Bae ◽  
Woosung Lee ◽  
...  
Keyword(s):  
Gas Sensing ◽  
Nanofiber Yarn ◽  
Sensing Platform

(Invited) Functionalization and Behavior in Aqueous Media of Silicon Surfaces for Improved Biochemical Sensing

2019 ◽  
Vol 35 (8) ◽  
pp. 101-107
Author(s):  
Jean-Noel Chazalviel ◽  
Philippe Allongue ◽  
Anne Chantal Gouget-Laemmel ◽  
Catherine Henry de Villeneuve ◽  
Anne Moraillon ◽  
...  
Keyword(s):  
Aqueous Media ◽  
Silicon Surfaces ◽  
Biochemical Sensing ◽  
And Behavior
Sign in / Sign up

Export Citation Format

Share Document