Modeling of epithelia transport phenomena related with the acetowhitening optical changes: potential for the in vivo diagnosis of cervical neoplasia

2008 ◽  
Author(s):  
George Papoutsoglou ◽  
Antonis Potirakis ◽  
Costas Balas
Keyword(s):  
Transport Phenomena ◽  
Cervical Neoplasia ◽  
In Vivo Diagnosis ◽  
Epithelia Transport

The performance of fluorescence and reflectance spectroscopy for the in vivo diagnosis of cervical neoplasia; point probe versus multispectral approaches

2007 ◽  
Vol 107 (1) ◽  
pp. S248-S255 ◽  
Author(s):  
J. Adrian Freeberg ◽  
J.L. Benedet ◽  
Calum MacAulay ◽  
Loyd A. West ◽  
Michele Follen
Keyword(s):  
Reflectance Spectroscopy ◽  
Cervical Neoplasia ◽  
In Vivo Diagnosis

The clinical effectiveness of fluorescence and reflectance spectroscopy for the in vivo diagnosis of cervical neoplasia: An analysis by phase of trial design

2007 ◽  
Vol 107 (1) ◽  
pp. S270-S280 ◽  
Author(s):  
J. Adrian Freeberg ◽  
J.L. Benedet ◽  
L.A. West ◽  
E.N. Atkinson ◽  
Calum MacAulay ◽  
...  
Keyword(s):  
Trial Design ◽  
Clinical Effectiveness ◽  
Reflectance Spectroscopy ◽  
Cervical Neoplasia ◽  
In Vivo Diagnosis

scholarly journals Aptamer Applications in Emerging Viral Diseases

2021 ◽  
Vol 14 (7) ◽  
pp. 622
Author(s):  
Arne Krüger ◽  
Ana Paula de Jesus Santos ◽  
Vanessa de Sá ◽  
Henning Ulrich ◽  
Carsten Wrenger
Keyword(s):  
Virus Assembly ◽  
Viral Diseases ◽  
Tissue Penetration ◽  
Rna Molecules ◽  
Viral Particles ◽  
Pharmacokinetic Properties ◽  
Oligonucleotide Library ◽  
In Vivo Diagnosis ◽  
Emerging Viral Diseases

Aptamers are single-stranded DNA or RNA molecules which are submitted to a process denominated SELEX. SELEX uses reiterative screening of a random oligonucleotide library to identify high-affinity binders to a chosen target, which may be a peptide, protein, or entire cells or viral particles. Aptamers can rival antibodies in target recognition, and benefit from their non-proteic nature, ease of modification, increased stability, and pharmacokinetic properties. This turns them into ideal candidates for diagnostic as well as therapeutic applications. Here, we review the recent accomplishments in the development of aptamers targeting emerging viral diseases, with emphasis on recent findings of aptamers binding to coronaviruses. We focus on aptamer development for diagnosis, including biosensors, in addition to aptamer modifications for stabilization in body fluids and tissue penetration. Such aptamers are aimed at in vivo diagnosis and treatment, such as quantification of viral load and blocking host cell invasion, virus assembly, or replication, respectively. Although there are currently no in vivo applications of aptamers in combating viral diseases, such strategies are promising for therapy development in the future.

High-Resolution Confocal Endomicroscopy Probe System for In Vivo Diagnosis of Colorectal Neoplasia

2008 ◽  
Vol 135 (1) ◽  
pp. 295 ◽  
Author(s):  
Anna M. Buchner ◽  
Marwan S. Ghabril ◽  
Murli Krishna ◽  
Herbert C. Wolfsen ◽  
Michael B. Wallace
Keyword(s):  
High Resolution ◽  
Colorectal Neoplasia ◽  
Confocal Endomicroscopy ◽  
Probe System ◽  
In Vivo Diagnosis

Multimodal endoscopic imaging and Raman spectroscopy for improving in vivo diagnosis of gastric malignancies during clinical gastroscopy

2010 ◽  
Author(s):  
Mads Sylvest Bergholt ◽  
Wei Zheng ◽  
Kan Lin ◽  
Khek Yu Ho ◽  
Khay Guan Yeoh ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Endoscopic Imaging ◽  
In Vivo Diagnosis

scholarly journals Real-time In vivo Diagnosis of Nasopharyngeal Carcinoma Using Rapid Fiber-Optic Raman Spectroscopy

Theranostics ◽  
2017 ◽  
Vol 7 (14) ◽  
pp. 3517-3526 ◽  
Author(s):  
Kan Lin ◽  
Wei Zheng ◽  
Chwee Ming Lim ◽  
Zhiwei Huang
Keyword(s):  
Raman Spectroscopy ◽  
Nasopharyngeal Carcinoma ◽  
Real Time ◽  
Fiber Optic ◽  
In Vivo Diagnosis
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