Non-invasive monitoring and quantitative analysis of patch test reactions by reflectance spectrophotometry, laser Doppler flowmetry and transepidermal water loss

2008 ◽  
Author(s):  
Natalja Skrebova Eikje ◽  
Seiji Arase
2021 ◽  
Vol 01 ◽  
Author(s):  
Anna Olejnik ◽  
Aleksandra Galarda ◽  
Joanna Goscianska

Background: Cannabis Sativa seed oil has become more and more popular in cosmetic industry mainly due to the high content of antioxidants and unsaturated fatty acids that are desirable in formulations because they prevent moisture loss and reduce the occurrence of dry skin. Objective: The aim of this study was to determine the effect of Cannabis Sativa seed oil on skin parameters such as hydration and transepidermal water loss. Methods: The in vivo tests on volunteers with combination skin were performed by using non-invasive methods by using corneometer and tewameter. Results: The obtained results proved that Cannabis Sativa seed oil improved skin condition. The transepidermal water loss decreased because the lipophilic components of the oil formulation tend to form an occlusive layer on the epidermis surface. The highest increase in skin hydration was observed after one week of treatment. Conclusion: These results confirmed that Cannabis Sativa seed oil has strong moisturizing properties and can be recommended as a natural based skin conditioning agent.


2000 ◽  
Vol 13 (1) ◽  
pp. 39-51 ◽  
Author(s):  
V. Zuang ◽  
G. Archer ◽  
C. Rona ◽  
M. Vignini ◽  
M. Mosca ◽  
...  

1988 ◽  
Vol 74 (2) ◽  
pp. 119-121 ◽  
Author(s):  
C. Orlandi ◽  
C. J. Dunn ◽  
L. G. Cutshaw

1. A non-invasive method is described for the assessment of angiogenesis in chronic inflammation using laser-Doppler flowmetry. 2. Significant increases in capillary blood flow were seen on days 5 and 7 after induction of subcutaneous granulomatous lesions, as compared with control skin. 3. Changes in blood flow were accompanied by changes in pulsatile flow pattern and by an intense angiogenic response observed by light microscopy. 4. The potential application of laser-Doppler flowmetry to quantitative and qualitative studies of evolving angiogenesis in pathological responses is discussed.


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