Surface enhanced Raman spectroscopy on chip

2008 ◽  
Author(s):  
Jorg Hubner ◽  
Thomas Anhøj ◽  
Sarah Pedersen ◽  
Dan A. Zauner ◽  
Anders M. Jorgensen ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Surface Enhanced Raman Spectroscopy ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
On Chip

scholarly journals On-chip monitoring of chemical syntheses in microdroplets via surface-enhanced Raman spectroscopy

2015 ◽  
Vol 51 (41) ◽  
pp. 8588-8591 ◽  
Author(s):  
T.-A. Meier ◽  
R. J. Beulig ◽  
E. Klinge ◽  
M. Fuss ◽  
S. Ohla ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Real Time ◽  
Surface Enhanced Raman Spectroscopy ◽  
Proof Of Concept ◽  
Organic Syntheses ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
On Chip

An approach for inline monitoring of organic syntheses in a microfluidic droplet chip via surface-enhanced Raman spectroscopy is presented. In a proof of concept it was successfully applied to follow thiazole syntheses in real-time.

scholarly journals Silver nanoparticle on zinc oxide array for label-free detection of opioids through surface-enhanced raman spectroscopy

RSC Advances ◽  
2021 ◽  
Vol 11 (19) ◽  
pp. 11329-11337
Author(s):  
Michael Zhang ◽  
Congran Jin ◽  
Yuan Nie ◽  
Yundong Ren ◽  
Nanjing Hao ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Zinc Oxide ◽  
Surface Enhanced Raman Spectroscopy ◽  
Great Accuracy ◽  
Label Free ◽  
Ag Nanoparticle ◽  
Label Free Detection ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
On Chip

A plasmonic Ag nanoparticle decorated ZnO array on-chip sensor was developed for label-free detection of opioids through surface-enhanced Raman spectroscopy. The sensor reliably detects opioids as low as 90 ng mL−1 in human blood serum with great accuracy and sensitivity.

On-chip integration of novel Au electrode with a higher order three-dimensional layer stack nanostructure for surface-enhanced Raman spectroscopy

RSC Advances ◽  
2015 ◽  
Vol 5 (89) ◽  
pp. 73194-73201 ◽  
Author(s):  
Akinobu Yamaguchi ◽  
Takao Fukuoka ◽  
Ryohei Hara ◽  
Kazuhisa Kuroda ◽  
Ryo Takahashi ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Self Assembly ◽  
Three Dimensional ◽  
Surface Enhanced Raman Spectroscopy ◽  
Higher Order ◽  
Au Electrode ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
On Chip

We develop a novel in situ surface-enhanced Raman spectroscopy (SERS) platform with three-dimensional nanostructure gold electrodes using the competitive self-assembly between dielectrophoresis and convective aggregation.

Bacterial detection and differentiation via direct volatile organic compound sensing with surface enhanced Raman spectroscopy

2017 ◽  
Author(s):  
Caitlin S. DeJong ◽  
David I. Wang ◽  
Aleksandr Polyakov ◽  
Anita Rogacs ◽  
Steven J. Simske ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Bacterial Infections ◽  
Direct Detection ◽  
Point Of Care ◽  
Surface Enhanced Raman Spectroscopy ◽  
E Coli ◽  
Recent Emergence ◽  
Surface Enhanced ◽  
Volatile Organic ◽  
Surface Enhanced Raman

Through the direct detection of bacterial volatile organic compounds (VOCs), via surface enhanced Raman spectroscopy (SERS), we report here a reconfigurable assay for the identification and monitoring of bacteria. We demonstrate differentiation between highly clinically relevant organisms: <i>Escherichia coli</i>, <i>Enterobacter cloacae</i>, and <i>Serratia marcescens</i>. This is the first differentiation of bacteria via SERS of bacterial VOC signatures. The assay also detected as few as 10 CFU/ml of <i>E. coli</i> in under 12 hrs, and detected <i>E. coli</i> from whole human blood and human urine in 16 hrs at clinically relevant concentrations of 10<sup>3</sup> CFU/ml and 10<sup>4</sup> CFU/ml, respectively. In addition, the recent emergence of portable Raman spectrometers uniquely allows SERS to bring VOC detection to point-of-care settings for diagnosing bacterial infections.

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