Optical properties of core-multishell quantum dots and their imaging applications in cancer cells

2007 ◽  
Author(s):  
Y. Liu ◽  
P. Chen ◽  
L. Lin ◽  
G.-Q. Tang ◽  
G.-G. Mu
Keyword(s):  
Quantum Dots ◽  
Optical Properties ◽  
Cancer Cells

Confocal Study of Specific Targeting of Quantum Dot Nanocomposites to Cancer Cells

2005 ◽  
Vol 288-289 ◽  
pp. 155-158 ◽  
Author(s):  
Yong Zhang ◽  
J. Zhang
Keyword(s):  
Quantum Dots ◽  
Optical Properties ◽  
Folic Acid ◽  
Cancer Cells ◽  
Carboxyl Groups ◽  
Target Cells ◽  
Intracellular Uptake ◽  
Cellular Targeting ◽  
Specific Targeting ◽  
The Ideal

Targeting of drugs and therapeutic materials to target cells or designated intracellular locations relies upon their cellular / sub-cellular targeting and trafficking. The ideal optical properties of quantum dots offer the possibility of using them as fluorescent probes to study the intracellular uptake and pathway of drugs or biomolecules. Quantum dots, ZnS coated CdSe, were synthesized and successfully incorporated into polystyrene (PS) particles grafted with carboxyl groups and folic acid was attached to the nanoparticle surfaces. The nanocomposites were monodisperse and highly luminescent, and their intracellular uptake to cancer cells was investigated using confocal microscopy.

Aligning CdS Quantum Dots in Apo-Ferritin Protein and PS-b-P2VP Organic Templates

2013 ◽  
Vol 832 ◽  
pp. 675-680
Author(s):  
S.A. Shamsudin ◽  
Hirokazu Hasegawa ◽  
Mikihito Takenaka ◽  
Saijo Kenji
Keyword(s):  
Quantum Dots ◽  
Optical Properties ◽  
Cancer Cells ◽  
Cadmium Sulphide ◽  
Cds Quantum Dots ◽  
Organic Templates ◽  
Ps I ◽  
Cds Qds ◽  
Guest System ◽  
Photo Stability

Quantum dots (QDs) have a great potential to be applied as a biosensor to detect cancer cells because of their properties such as high photoluminescence, photo stability, narrow peak of luminescence, etc. However, cadmium sulphide (CdS) quantum dots are toxic and hydrophobic, making it impossible to be applied into biomaterials. A template is needed to make CdS QDs nontoxic and hydrophilic. The optical properties of these QDs are needed to be protected. To achieve this purpose, the template for CdS QDs has been designed by capping CdS QDs with apo-ferritin shells before aligning them onto cylindrical perpendicular PS-b-P2VP template, with the aim of locating CdS QDs appropriately in sequence. A host-guest system can be developed.

Semiconductor Quantum Dots for Multicolor Fluorescence Imaging and Spectroscopy of Single Cancer Cells

2003 ◽  
Vol 773 ◽  
Author(s):  
Xiaohu Gao ◽  
Shuming Nie ◽  
Wallace H. Coulter
Keyword(s):  
Quantum Dots ◽  
Cancer Cells ◽  
Fluorescence Imaging ◽  
Organic Dyes ◽  
Fluorescent Proteins ◽  
Single Cells ◽  
Quantitative Imaging ◽  
Semiconductor Quantum Dots ◽  
Single Cancer ◽  
Imaging And Spectroscopy

AbstractLuminescent quantum dots (QDs) are emerging as a new class of biological labels with unique properties and applications that are not available from traditional organic dyes and fluorescent proteins. Here we report new developments in using semiconductor quantum dots for quantitative imaging and spectroscopy of single cancer cells. We show that both live and fixed cells can be labeled with multicolor QDs, and that single cells can be analyzed by fluorescence imaging and wavelength-resolved spectroscopy. These results raise new possibilities in cancer imaging, molecular profiling, and disease staging.

Synthesis, Characterization and Optical Properties of CdSe and ZnSe Quantum Dots

2017 ◽  
Vol 7 (1) ◽  
pp. 73-79 ◽  
Author(s):  
Deepak Kumar Gupta ◽  
Mahesh Verma ◽  
Dinesh Patidar ◽  
Kananbala Sharma ◽  
N.S. Saxena
Keyword(s):  
Quantum Dots ◽  
Optical Properties

Investigation of the Surface Passivation Effect on the Optical Properties of CsPbBr3 Perovskite Quantum Dots

2021 ◽  
Vol 23 ◽  
pp. 100948
Author(s):  
Saif M.H. Qaid ◽  
Hamid M. Ghaithan ◽  
Bandar Ali Al-Asbahi ◽  
Abdullah S. Aldwayyan
Keyword(s):  
Quantum Dots ◽  
Optical Properties ◽  
Surface Passivation ◽  
Perovskite Quantum Dots
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