Optical coherence tomography among medical imaging modalities: potential and limitations

2007 ◽  
Author(s):  
Natalia Gladkova ◽  
Elena Zagaynova ◽  
Natalia Shakhova ◽  
Alexander M. Sergeev ◽  
Valentin Gelikonov ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Medical Imaging ◽  
Imaging Modalities ◽  
Optical Coherence

Imaging in diabetic retinopathy

2020 ◽  
pp. 161-170
Author(s):  
Sarita Jacob ◽  
Ramesh R. Sivaraj
Keyword(s):  
Optical Coherence Tomography ◽  
Diabetic Retinopathy ◽  
Prognostic Value ◽  
Diabetic Macular Oedema ◽  
Imaging Modalities ◽  
Wide Field ◽  
Optical Coherence ◽  
Diabetic Maculopathy ◽  
Fundus Fluorescein Angiography ◽  
Diagnostic And Prognostic Value

Imaging in diabetic retinopathy (DR) has developed over the years and the advantages are multifold. Various imaging modalities are currently available, which is of great diagnostic and prognostic value in the management of DR. Optical coherence tomography (OCT) has revolutionized the management of diabetic maculopathy. OCT has now become indispensable for initiating and assessing diabetic macular oedema (DMO) while on treatment with intravitreal injections. Recent introduction of optical coherence tomography angiography (OCTA) has significantly reduced the need for fundus fluorescein angiography (FFA) for macular ischaemia and proliferative retinopathy. Ultra-wide field (UWF) imaging modalities for colour fundus and UWF FFA are very useful to document and assess overall retinal state highlighting the periphery. Bscan ultrasonography of the fundus is an useful tool to assess retinal status in proliferative DR with vitreous haemorrhage.

Detection, localization, and characterization of vision-threatening features of microaneurysms using optical coherence tomography angiography in diabetic maculopathy

2020 ◽  
pp. 112067212092460 ◽  
Author(s):  
Anadi Khatri ◽  
Eli Pradhan ◽  
Bal Kumar KC ◽  
Muna Kharel ◽  
Roshija Khanal Rijal ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Confidence Interval ◽  
Odds Ratio ◽  
Optical Coherence Tomography Angiography ◽  
High Flow ◽  
Imaging Modalities ◽  
Low Flow ◽  
Optical Coherence ◽  
Diabetic Maculopathy ◽  
Capillary Plexus

Introduction Diabetic maculopathy is a leading retinal cause of blindness. This study was conducted using optical coherence tomography angiography and noninvasive imaging modalities. Microaneurysms were evaluated for location, flow, and adjacent retinal tissue changes to establish knowledge of possible vision-threatening features. Methodology: This is a hospital-based, cross-sectional observational study. Eighteen patients with diabetic maculopathy were included in the study. Fundus photo, red-free filter image, infrared images with shadowgrams, optical coherence tomography cross sections, and optical coherence tomography angiography were analyzed. Mean, standard deviation, odds ratio, and 95% confidence interval were used for statistical analysis, and p-value of <0.05 was considered statistically significant where applicable. Results A total of 64 microaneurysms were evaluated. Forty-six (71.8%) microaneurysms were identifiable in all imaging modalities. In total, 53 (82.8%) were high-flow microaneurysms and 11 (17.2%) were low-flow microaneurysms. Thirty-eight of the high-flow microaneurysms (71.6% of the high-flow microaneurysms) were found in the deep capillary plexus, while only 15 (28.4% of the high-flow microaneurysms) were found in the superficial capillary plexus. Twenty-seven (71%) of the high-flow microaneurysms in deep capillary plexus were present in the areas of retinal thickening (odds ratio: 4.5, 95% confidence interval: 1.26–16.0, p = 0.02). A total of 11 microaneurysms were classified as low-flow microaneurysms and identified using fundus photo, red-free filter image, infrared images with shadowgrams, and optical coherence tomography—cross sections. They had a tendency to be present in the areas of decreased capillary plexus density (odds ratio: 25.6, 95% confidence interval: 5.09–128.7, p = 0.001). Conclusion Noninvasive imaging modalities combined with optical coherence tomography angiography can provide valuable information regarding microaneurysms. Certain features such as location and flow may help in predicting impending macular edema or ischemia.

Optical coherence tomography

2021 ◽  
pp. 67-70
Author(s):  
Keyvan Karimi Galougahi ◽  
Tomasz Roleder ◽  
Akiko Maehara ◽  
Ziad A. Ali
Keyword(s):  
Optical Coherence Tomography ◽  
High Resolution ◽  
Vascular Tissue ◽  
Imaging Modalities ◽  
Optical Coherence ◽  
Diagnostic Applications

Optical coherence tomography enables fast, high-resolution visualization of vascular tissue that is often not feasible by other imaging modalities. This chapter provides an overview of diagnostic applications of optical coherence tomography in coronary pathologies and the unique insights that optical coherence tomography can provide in percutaneous and surgical cardiovascular procedures.

scholarly journals A Post-market, Multi-vessel Evaluation of the Imaging of Peripheral Arteries for Diagnostic Purposes Comparing Optical Coherence Tomography and Intravascular Ultrasound Imaging (SCAN)

2019 ◽  
Author(s):  
Edward Pavillard ◽  
Luke Sewell
Keyword(s):  
Optical Coherence Tomography ◽  
Intravascular Ultrasound ◽  
Treatment Strategy ◽  
Intraclass Correlation ◽  
Imaging Systems ◽  
Imaging Modalities ◽  
Optical Coherence ◽  
Luminal Diameter ◽  
The Mean ◽  
Oct Imaging

Abstract Background: Intravascular imaging plays an important part in diagnosis of vascular conditions and providing insight for treatment strategy. Two main imaging modalities are intravascular ultrasound (IVUS) and optical coherence tomography (OCT). The objective of this study was to prove non-inferiority of OCT imaging to IVUS images in matched segments of peripheral vessels in patients with suspected peripheral vascular disease.Methods: The SCAN study was a prospective, non-inferiority clinical study of matched IVUS and OCT images collected along defined segments of peripheral vessels from twelve subjects (mean age 68 10.3 years; 10 men) displaying symptoms of vascular disease. Luminal diameters were measured by both imaging systems at the distal, middle, and proximal points of the defined segments. Three blinded interventional radiologists evaluated the quality of both imaging modalities in identifying lMann-Whitney-Wilcoxon testing. Intrareader reproducibility was calculated by intraclass correlation (ICC) analysis. Results: The mean scoringof plaque, calcification, and vascular stent struts by the three readers was significant better in terms of image quality for OCT than IVUS (p<0.001, p=0.001, p=0.004, respectively). The mean scores of vessel wall component visibility and artifacts generated by the two imaging systems were not significantly different (p=0.19, p=0.07, respectively). Mean vessel luminal diameter and area at three specific locations within the vessels were not significantly different between the two imaging modalities. No patient injury, adverse effect or device malfunction were noted during thestudy. Conclusions: Imaging byOCT provides the physician with better visualization of some vessel and plaque chacteristics, but both IVUS and OCT imaging are safe and effective methods of examining peripheral vessels in order to perform diagnostic assessment of peripheral vessels and provide information necessary for the treatment strategy of peripheral artery disease.

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