Assessment of fetal heart disorder by means of fetal magnetocardiography

2006 ◽  
Author(s):  
Maria Łozińska ◽  
Zbigniew Dunajski
Author(s):  
Rong Tao ◽  
Elena-Anda Popescu ◽  
William B. Drake ◽  
David Jackson ◽  
Mihai Popescu

Fetal magnetocardiography (fMCG) records the magnetic field generated by the electrical activity associated with the fetal cardiac muscle contraction and has emerged as an attractive tool for monitoring the fetal heart in-utero. The magnetic sensor array is placed above the maternal abdomen to receive the extremely weak magnetic signal of the fetal heart from 20 weeks of gestation onward. fMCG outperforms fetal electrocardiography (fECG) in its notably superior signal quality, as the magnetic field is considerably less affected by tissues with low electrical conductivity surrounding the fetal heart [1], which can drastically diminish the fECG signal amplitude.


Author(s):  
K.C. Feng-Chen ◽  
F.B. Essien ◽  
K.J. Prestwidge ◽  
J.T. Cheng ◽  
C.L. Shen

The physiology of the fetal heart differs significantly from that of the mature post-natal organ: e.g., the metabolic supply for adult cardiac contraction relies mainly on fatty acids; whereas, the fetal heart uses carbohydrates as its primary energy source. Limited morphological descriptions of the developing myocardium have appeared. However, additional studies are required to elucidate the ultrastructural changes occuring in the perinatal period when enormous physiological adjustments are made. Although adult animals are most often used in toxocological and pathological analyses, it is also important to investigate fetal cardiac responsiveness to various agents. The vulnerability of the ultrastructure of the fetal mouse myocardium to genetic and environmental assault is the subject of this report. The genetically determined effect on the heart was observed in mouse embryos homozygous for the cab (cardiac abnormality) mutation discovered by Essien.


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