Wavelet differentiation of optoacoustic signals for monitoring of total hemoglobin concentration and oxygen saturation level in small blood vessels

Author(s):  
I. Patrikeev ◽  
H.-P. Brecht ◽  
Y. Y. Petrov ◽  
I. Y. Petrova ◽  
D. S. Prough ◽  
...  
2021 ◽  
Vol 2 (1) ◽  
pp. 38-43
Author(s):  
Abdullajon Komilov ◽  
◽  
Madinabonu Sultonova ◽  
Durdona Orifjonova

Today, the COVID-19 pandemic is one of the most pressing problems facing humanity. Therefore, reducing the population's level of infection with this virus is one of our government's main tasks.Therefore, it is necessary to isolate patients with chronic diseases as much as possible. Clients are more likely to be infected with caronavirus due to their age and the presence of underlying medical conditions.Limiting direct contact between such patients and observing healthcare professionals significantly reduces the patient's chances of contracting caronavirus.The article proposes a device design that allows for remote automatic monitoring of patients' condition being treated at home by an observing medical professional.With the proposed device's help, the patient's blood oxygen saturation level is automatically and remotely controlled. The device is built on an Arduino board.The use of the device greatly reduces the likelihood of contracting caronavirus in patients receiving home treatment.This could be one of the most important decisions in maintaining the health of the population today.


2010 ◽  
Vol 4 (2) ◽  
Author(s):  
Thao P. Do ◽  
Lindsey J. Eubank ◽  
Devin S. Coulter ◽  
John M. Freihaut ◽  
Carlos E. Guevara ◽  
...  

When an infant is born prematurely, there are a number of health risks. Among these are underdeveloped lungs, which can lead to abnormal gas exchange of oxygen or hypoxemia. Hypoxemia is treated through oxygen therapy, which involves the delivery of supplemental oxygen to the patient but there are risks associated with this method. Risks include retinopathy, which can cause eye damage when oxygen concentration is too high, and brain damage, when the concentration is too low [1]. Supplemental oxygen concentration must be controlled rigorously. Currently healthcare staff monitors infants’ blood oxygen saturation level using a pulse oximeter. They manually adjust the oxygen concentration using an air-oxygen blender. Inconsistent manual adjustments can produce excessive fluctuations and cause the actual oxygen saturation level to deviate from the target value. Precision and accuracy are compromised. This project develops an automatic oxygen delivery system that regulates the supplemental oxygen concentration to obtain a target blood oxygen saturation level. A microprocessor uses a LABVIEW® program to analyze pulse oximeter and analyzer readings and control electronic valves in a redesigned air-oxygen blender. A user panel receives a target saturation level, displays patient data, and signals alarms when necessary. The prototype construction and testing began February 2010.


1979 ◽  
Vol 47 (2) ◽  
pp. 337-341 ◽  
Author(s):  
M. Samaja ◽  
A. Veicsteinas ◽  
P. Cerretelli

Oxygen equilibrium curves on blood within 6 h from sampling have been estimated from polarographic measurements of oxyhemoglobin concentration, in 13 male 14- to 50-yr old Sherpas residing at 3,850 m above sea level (Kumjung, Nepal). In samples with red blood cell counts = 4.7 +/- 0.8 (SD) x 10(6)/mm3, total hemoglobin concentration [Hb] = 17.0 +/- 1.9 g/dl, and hematocrit = 53.3 +/- 5.0, the mean oxygen half-saturation of hemoglobin (P50) (pH = 7.4 and PCO2 = 40 Torr) was 27.3 +/- 1.8 Torr. The P50 of altitude Sherpas was not significantly different from that of acclimatized lowlanders (28.2 +/- 1.3; n = 7), sea-level Caucasian residents (26.5 +/- 1.0; n = 17), and Sherpas at sea level (27.1; n = 3). The 2,3-diphosphoglyceric acid-to-hemoglobin concentration ratio ([2,3-DPG]/[Hb]) in altitude Sherpas was 1.22 +/- 0.03, the same as that of acclimatized Caucasians (1.22 +/- 0.10). The Bohr effect measured for the blood of one altitude Sherpas by the ratio deltalog P50/deltapH was -0.32 and -0.45 at PCO2 levels of 40 and 20 Torr, respectively. These values are not significantly different from those found in Caucasians at sea level where deltalog P50/deltalpH was -0.35 and -0.42, respectively. It is concluded that the P50 in native highlanders is not significantly different from that observed in sea-level dwellers. [2,3-DPG]/[Hb] at altitude, both in natives and in newcomers, is 20% higher than in sea-level residents.


Author(s):  
I. Y. Petrova ◽  
D. S. Prough ◽  
Y. Y. Petrov ◽  
H.- P. F. Brecht ◽  
C. Svensen ◽  
...  

1986 ◽  
Vol 32 (6) ◽  
pp. 972-978 ◽  
Author(s):  
A Zwart ◽  
E J van Kampen ◽  
W G Zijlstra

Abstract Our recently developed multiwavelength method for multi-component analysis of hemoglobin (Hb) derivatives (Clin Chem 1984;30:373-379) was adapted for routine use in the clinical chemical laboratory. The method was applied in 4066 determinations on blood specimens from patients awaiting major surgery (n = 3863) or visiting the outpatient department for pulmonary disease (n = 203). Mean total hemoglobin concentration was 141 (SD 14) g/L. The proportion of HbCO was slightly to moderately increased (1.5-10.0%) in 36.5% of all patients; in a few cases it was as high as 15%. Mean methemoglobin was 0.4% (SD 0.2%) in the surgical patients, but 1.5% (SD 0.8%) in the patients with pulmonary disease. In some patients of the latter group the proportion of methemoglobin amounted to 5%. Sulfhemoglobin was found less than 0.4% in all specimens. Interference by paraproteins and by increased concentrations of bilirubin and lipids in plasma was easily detected by means of the performance checks provided by the spectrophotometer (an HP 8451 UV/Vis). The method is equally suitable for measuring blood samples containing fetal hemoglobin.


Sign in / Sign up

Export Citation Format

Share Document