Mean absorbed dose to mouse in micro-CT imaging with an ultrafast laser-based x-ray source

2007 ◽  
Author(s):  
Andrzej Krol ◽  
Hongwei Ye ◽  
Russell Kincaid ◽  
John Boone ◽  
Marina Servol ◽  
...  
2021 ◽  
Vol 203 ◽  
pp. 108394
Author(s):  
Sergey Y. Tkachev ◽  
Boris I. Mitrin ◽  
Nikolay S. Karnaukhov ◽  
Evgeniy V. Sadyrin ◽  
Mark V. Voloshin ◽  
...  
Keyword(s):  
Micro Ct ◽  
X Ray ◽  

Author(s):  
Julian R. Jones ◽  
Georgina E. Milroy ◽  
Ruth Cameron ◽  
William Bonfield ◽  
Larry L. Hench
Keyword(s):  
Micro Ct ◽  

2016 ◽  
Vol 11 (01) ◽  
pp. C01005-C01005 ◽  
Author(s):  
T. Fíla ◽  
I. Kumpová ◽  
P. Koudelka ◽  
P. Zlámal ◽  
D. Vavřík ◽  
...  

2018 ◽  
Vol 13 (12) ◽  
pp. C12006-C12006 ◽  
Author(s):  
D. Vavřík ◽  
D. Kytýř ◽  
S. Mühleder ◽  
M. Vopálenský ◽  
P. Beneš ◽  
...  

2010 ◽  
Vol 37 (10) ◽  
pp. 5306-5312 ◽  
Author(s):  
Guohua Cao ◽  
Laurel M. Burk ◽  
Yueh Z. Lee ◽  
Xiomara Calderon-Colon ◽  
Shabana Sultana ◽  
...  

2008 ◽  
Author(s):  
Russell Kincaid ◽  
Andrzej Krol ◽  
Sylvain Fourmaux ◽  
Jean-Claude Kieffer ◽  
Cristina Serbanescu ◽  
...  

2020 ◽  
Author(s):  
Michaela Kavkova ◽  
Tomas Zikmund ◽  
Annu Kala ◽  
Jakub Salplachta ◽  
Stephanie Proskauer Pena ◽  
...  

Abstract Amyloid plaques are small (~50 μm), highly-dense aggregates of amyloid beta (Aβ) protein in brain tissue, supposed to play a key role in pathogenesis of Alzheimer’s disease (AD). Plaques´ in vivo detection, spatial distribution and quantitative characterization could be an essential marker in diagnostics and evaluation of AD progress. However, current imaging methods in clinics possess substantial limits in sensitivity towards Aβ plaques to play a considerable role in AD screening. Contrast enhanced X-ray micro computed tomography (micro CT) is an emerging highly sensitive imaging technique capable of high resolution visualization of rodent brain. In this study we show the absorption based contrast enhanced X-ray micro CT imaging is viable method for detection and 3D analysis of Aβ plaques in transgenic rodent models of Alzheimer’s disease. Using iodine contrasted brain tissue isolated from the Tg-F344-AD rat model we show the micro CT imaging is capable of precise imaging of Aβ plaques, making possible to further analyze various aspects of their 3D spatial distribution and other properties.


Sign in / Sign up

Export Citation Format

Share Document