Application of adaptive optics: optical coherence tomography for in vivo imaging of microscopic structures in the retina and optic nerve head

2007 ◽  
Author(s):  
Robert J. Zawadzki ◽  
Yan Zhang II ◽  
Steven M. Jones ◽  
Stacey S. Choi ◽  
Barry Cense ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optic Nerve ◽  
Adaptive Optics ◽  
Optic Nerve Head ◽  
In Vivo Imaging ◽  
Optical Coherence

scholarly journals In vivo analysis of glaucoma-related features within the optic nerve head using enhanced depth imaging optical coherence tomography

PLoS ONE ◽  
2017 ◽  
Vol 12 (7) ◽  
pp. e0180128 ◽  
Author(s):  
Tiago S. Prata ◽  
Flavio S. Lopes ◽  
Vitor G. Prado ◽  
Izabela Almeida ◽  
Igor Matsubara ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optic Nerve ◽  
Optic Nerve Head ◽  
Enhanced Depth Imaging ◽  
Optical Coherence ◽  
Depth Imaging ◽  
In Vivo Analysis ◽  
Imaging Optical Coherence Tomography

scholarly journals Ultra-high resolution adaptive optics: optical coherence tomography for in vivo imaging of healthy and diseased retinal structures

2008 ◽  
Author(s):  
Robert J. Zawadzki ◽  
Yan Zhang ◽  
Steven M. Jones ◽  
Stacey S. Choi ◽  
Barry Cense ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
High Resolution ◽  
Adaptive Optics ◽  
In Vivo Imaging ◽  
Optical Coherence

scholarly journals Morphological and vascular characteristics of the optic nerve head in normal guinea pigs

2021 ◽  
Author(s):  
Lei Guo ◽  
Jun Tao ◽  
Yang Tong ◽  
Shichao Chen ◽  
Xin Zhao ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optic Nerve ◽  
Optic Nerve Head ◽  
Refractive Error ◽  
Guinea Pigs ◽  
Linear Regression Analysis ◽  
Vascular Density ◽  
Optical Coherence ◽  
Vessel Length

Abstract The morphological and vascular characteristics of the optic nerve head (ONH) in normal guinea pigs remain unknown. Therefore, we aimed to investigate these parameters using optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA). We measured the refractive error, axial length, and intraocular pressure (IOP), and performed OCT and OCTA of the ONH in 3- and 4-week-old tricolour guinea pigs. A total of 208 right eyes from 208 normal guinea pigs were examined. The refractive error in the 3-week group was significantly larger than that in the 4-week group (p < 0.001), the IOP in the 3-week group was significantly lower than that in the 4-week group (p = 0.014), and the circumpapillary retinal nerve fibre layer (cpRNFL) thickness in the 3-week group was significantly larger than that in 4-week group (p = 0.048). There were no significant differences in the average vessel area, vascular density, total number of junctions, total vessel length, total number of endpoints, and vascular diameter between the two groups. However, an age-adjusted linear regression analysis revealed that total vessel length was positively associated with the cpRNFL thickness (p = 0.024) and negatively associated with IOP (p = 0.016). This is the first report on morphological and vascular characteristics of the ONH in normal guinea pigs based on in vivo OCT and OCTA imaging and quantification of ONH parameters. These results may contribute to further research on myopia and glaucoma using guinea pig models.

scholarly journals Adaptive-optics optical coherence tomography for high-resolution and high-speed 3D retinal in vivo imaging

2005 ◽  
Vol 13 (21) ◽  
pp. 8532 ◽  
Author(s):  
Robert J. Zawadzki ◽  
Steven M. Jones ◽  
Scot S. Olivier ◽  
Mingtao Zhao ◽  
Bradley A. Bower ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
High Resolution ◽  
Adaptive Optics ◽  
In Vivo Imaging ◽  
High Speed ◽  
Optical Coherence

scholarly journals In vivo imaging of human photoreceptor mosaic with wavefront sensorless adaptive optics optical coherence tomography

2015 ◽  
Vol 6 (2) ◽  
pp. 580 ◽  
Author(s):  
Kevin S. K. Wong ◽  
Yifan Jian ◽  
Michelle Cua ◽  
Stefano Bonora ◽  
Robert J. Zawadzki ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Adaptive Optics ◽  
In Vivo Imaging ◽  
Optical Coherence ◽  
Photoreceptor Mosaic
Sign in / Sign up

Export Citation Format

Share Document