Measuring electrical and mechanical properties of red blood cells with a double optical tweezers

2006 ◽  
Author(s):  
Adriana Fontes ◽  
Heloise P. Fernandes ◽  
Maria L. Barjas-Castro ◽  
André A. de Thomaz ◽  
Liliana d. Y. Pozzo ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Red Blood Cells ◽  
Optical Tweezers ◽  
Blood Cells

Mechanical Properties of Stored Red Blood Cells Using Optical Tweezers

Blood ◽  
1998 ◽  
Vol 92 (8) ◽  
pp. 2975-2977 ◽  
Author(s):  
R.R. Huruta ◽  
M.L. Barjas-Castro ◽  
S.T.O. Saad ◽  
F.F. Costa ◽  
A. Fontes ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Red Blood Cells ◽  
Optical Tweezers ◽  
Blood Cells

Mechanical properties of stored red blood cells using optical tweezers

2005 ◽  
Author(s):  
Adriana Fontes ◽  
Andre Alexandre de Thomaz ◽  
Liliana de Ysasa Pozzo ◽  
Maria de Lourdes Barjas-Castro ◽  
Marcelo M. Brandao ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Red Blood Cells ◽  
Optical Tweezers ◽  
Blood Cells

Measuring electrical and mechanical properties of red blood cells with double optical tweezers

2008 ◽  
Vol 13 (1) ◽  
pp. 014001 ◽  
Author(s):  
Adriana Fontes ◽  
Heloise P. Fernandes ◽  
André A. de Thomaz ◽  
Luiz C. Barbosa ◽  
Maria L. Barjas-Castro ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Red Blood Cells ◽  
Optical Tweezers ◽  
Blood Cells

Mechanical Properties of Stored Red Blood Cells Using Optical Tweezers

Blood ◽  
1998 ◽  
Vol 92 (8) ◽  
pp. 2975-2977
Author(s):  
R.R. Huruta ◽  
M.L. Barjas-Castro ◽  
S.T.O. Saad ◽  
F.F. Costa ◽  
A. Fontes ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Red Blood Cells ◽  
Optical Tweezers ◽  
Blood Cells

scholarly journals High-throughput assessment of mechanical properties of stem cell derived red blood cells, toward cellular downstream processing

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Ewa Guzniczak ◽  
Maryam Mohammad Zadeh ◽  
Fiona Dempsey ◽  
Melanie Jimenez ◽  
Henry Bock ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Stem Cell ◽  
Red Blood Cells ◽  
High Throughput ◽  
Blood Cells ◽  
Downstream Processing

scholarly journals Targeting spectrin redox switches to regulate the mechanoproperties of red blood cells

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Frederik Barbarino ◽  
Lucas Wäschenbach ◽  
Virginia Cavalho-Lemos ◽  
Melissa Dillenberger ◽  
Katja Becker ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Redox Regulation ◽  
Current Knowledge ◽  
Structural Characteristics ◽  
Functional Characterization ◽  
Physiological Role ◽  
Spectrin Cytoskeleton ◽  
Redox Switches

AbstractThe mechanical properties of red blood cells (RBCs) are fundamental for their physiological role as gas transporters. RBC flexibility and elasticity allow them to survive the hemodynamic changes in the different regions of the vascular tree, to dynamically contribute to the flow thereby decreasing vascular resistance, and to deform during the passage through narrower vessels. RBC mechanoproperties are conferred mainly by the structural characteristics of their cytoskeleton, which consists predominantly of a spectrin scaffold connected to the membrane via nodes of actin, ankyrin and adducin. Changes in redox state and treatment with thiol-targeting molecules decrease the deformability of RBCs and affect the structure and stability of the spectrin cytoskeleton, indicating that the spectrin cytoskeleton may contain redox switches. In this perspective review, we revise current knowledge about the structural and functional characterization of spectrin cysteine redox switches and discuss the current lines of research aiming to understand the role of redox regulation on RBC mechanical properties. These studies may provide novel functional targets to modulate RBC function, blood viscosity and flow, and tissue perfusion in disease conditions.

Probing the Red Blood Cells Aggregating Force With Optical Tweezers

2016 ◽  
Vol 22 (3) ◽  
pp. 365-370 ◽  
Author(s):  
Kisung Lee ◽  
Anna V. Danilina ◽  
Matti Kinnunen ◽  
Alexander V. Priezzhev ◽  
Igor Meglinski
Keyword(s):  
Red Blood Cells ◽  
Optical Tweezers ◽  
Blood Cells

Red Blood Cells in Patients with Arrhythmias Using Optical Tweezers Raman Spectroscopy

2011 ◽  
Vol 48 (2) ◽  
pp. 021701
Author(s):  
吴智辉 Wu Zhihui ◽  
莫华 Mo Hua ◽  
黄代政 Huang Daizheng ◽  
陈朝旺 Chen Chaowang
Keyword(s):  
Raman Spectroscopy ◽  
Red Blood Cells ◽  
Optical Tweezers ◽  
Blood Cells

Measurement of interaction forces between red blood cells in aggregates by optical tweezers

2012 ◽  
Vol 42 (6) ◽  
pp. 500-504 ◽  
Author(s):  
A Yu Maklygin ◽  
A V Priezzhev ◽  
A Karmenian ◽  
Sergei Yu Nikitin ◽  
I S Obolenskii ◽  
...  
Keyword(s):  
Red Blood Cells ◽  
Optical Tweezers ◽  
Blood Cells ◽  
Interaction Forces
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