Calibration and characterization of a low-background chamber in support of hardware-in-the-loop testing and modeling of infrared seekers

2006 ◽  
Author(s):  
Richard D. Tschiegg ◽  
Steven J. Conard ◽  
Patrick L. Thompson ◽  
Adriaan Carter
2018 ◽  
Vol 9 (1) ◽  
Author(s):  
Joel I. Perez-Perri ◽  
Birgit Rogell ◽  
Thomas Schwarzl ◽  
Frank Stein ◽  
Yang Zhou ◽  
...  

AbstractFollowing the realization that eukaryotic RNA-binding proteomes are substantially larger than anticipated, we must now understand their detailed composition and dynamics. Methods such as RNA interactome capture (RIC) have begun to address this need. However, limitations of RIC have been reported. Here we describe enhanced RNA interactome capture (eRIC), a method based on the use of an LNA-modified capture probe, which yields numerous advantages including greater specificity and increased signal-to-noise ratios compared to existing methods. In Jurkat cells, eRIC reduces the rRNA and DNA contamination by >10-fold compared to RIC and increases the detection of RNA-binding proteins. Due to its low background, eRIC also empowers comparative analyses of changes of RNA-bound proteomes missed by RIC. For example, in cells treated with dimethyloxalylglycine, which inhibits RNA demethylases, eRIC identifies m6A-responsive RNA-binding proteins that escape RIC. eRIC will facilitate the unbiased characterization of RBP dynamics in response to biological and pharmacological cues.


2021 ◽  
Vol 68 (3) ◽  
pp. 2703-2713 ◽  
Author(s):  
Efren Guillo-Sansano ◽  
Mazheruddin H. Syed ◽  
Andrew J. Roscoe ◽  
Graeme M. Burt ◽  
Federico Coffele

2000 ◽  
Author(s):  
Donald N. B. Hall ◽  
Klaus-Werner Hodapp ◽  
David L. Goldsmith ◽  
Craig A. Cabelli ◽  
Allan K. Haas ◽  
...  
Keyword(s):  

Author(s):  
Ian B. Hutchison ◽  
Craig L. Bull ◽  
William G. Marshall ◽  
Simon Parsons ◽  
Andrew J. Urquhart ◽  
...  

This study details the structural characterization of glycolide-h4 as a function of pressure to 6 GPa using neutron powder diffraction on the PEARL instrument at ISIS Neutron and Muon source. Glycolide-h4, rather than its deuterated isotopologue, was used in this study due to the difficulty of deuteration. The low background afforded by zirconia-toughened alumina anvils nevertheless enabled the collection of data suitable for structural analysis to be obtained to a pressure of 5 GPa. Glycolide-h4 undergoes a reconstructive phase transition at 0.15 GPa to a previously identified form (II), which is stable to 6 GPa.


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