Single molecule CdSe/ZnS quantum dot and gold nanoparticle detection in live neurons

2006 ◽  
Author(s):  
D. Lasne ◽  
L. Cognet ◽  
S. Berciaud ◽  
G. A. Blab ◽  
L. Groc ◽  
...  
Keyword(s):  
Quantum Dot ◽  
Gold Nanoparticle ◽  
Single Molecule ◽  
Nanoparticle Detection

Towards Single-Molecule Diagnostics Using Microfluidic Manipulation and Quantum Dot Nanosensors

2007 ◽  
Author(s):  
Hsin-Chih Yeh ◽  
Christopher M. Puleo ◽  
Yi-Ping Ho ◽  
Tza-Huei Wang
Keyword(s):  
Energy Transfer ◽  
Quantum Dot ◽  
Single Molecule ◽  
Dna Sequences ◽  
Mutational Analysis ◽  
Resonance Energy Transfer ◽  
Resonance Energy ◽  
Single Molecule Detection ◽  
Specific Analysis ◽  
Low Volume

In this report, we review several single-molecule detection (SMD) methods and newly developed nanocrystal-mediated single-fluorophore strategies for ultrasensitive and specific analysis of genomic sequences. These include techniques, such as quantum dot (QD)-mediated fluorescence resonance energy transfer (FRET) technology and dual-color fluorescence coincidence and colocalization analysis, which allow separation-free detection of low-abundance DNA sequences and mutational analysis of oncogenes. Microfluidic approaches developed for use with single-molecule detection to achieve rapid, low-volume, and quantitative analysis of nucleic acids, such as electrokinetic manipulation of single molecules and confinement of sub-nanoliter samples using microfluidic networks integrated with valves, are also discussed.

scholarly journals Novel Quantum Dot Probes for Single-Molecule Biophysics

2014 ◽  
Vol 106 (2) ◽  
pp. 633a
Author(s):  
Sara M. Wichner ◽  
Mark A. DeWitt ◽  
Bruce E. Cohen ◽  
Ahmet Yildiz
Keyword(s):  
Quantum Dot ◽  
Single Molecule ◽  
Single Molecule Biophysics

scholarly journals λ/2 Fabry Pérot micro-resonators in single molecule spectroscopy

2018 ◽  
Vol 190 ◽  
pp. 02007
Author(s):  
Alfred J. Meixner ◽  
Frank Wackenhut ◽  
Alexander Konrad ◽  
Michael Metzger ◽  
Marc Brecht
Keyword(s):  
Energy Transfer ◽  
Quantum Yield ◽  
Quantum Dot ◽  
Single Molecule ◽  
Single Molecule Spectroscopy ◽  
Radiative Relaxation ◽  
Fabry Perot ◽  
Förster Energy Transfer ◽  
Micro Resonator ◽  
Dye Molecule

Embedded in a tuneable λ/2-FabryPérot micro-resonator the radiative relaxation of a dye molecule or quantum dot can reproducibly be modified allowing to determine their quantum yield, control Förster energy-transfer or localize them with nanometer precision.

A highly sensitive and label-free electrochemiluminescence immunosensor for beta 2-microglobulin

2017 ◽  
Vol 9 (17) ◽  
pp. 2570-2577 ◽  
Author(s):  
Mohammad Rizwan ◽  
Noor Faizah Mohd-Naim ◽  
Natasha Ann Keasberry ◽  
Minhaz Uddin Ahmed
Keyword(s):  
Quantum Dot ◽  
Cadmium Selenide ◽  
Gold Nanoparticle ◽  
Label Free ◽  
Screen Printed Electrode ◽  
Highly Sensitive ◽  
Beta 2 ◽  
Beta 2 Microglobulin ◽  
First Time ◽  
Screen Printed

A highly sensitive and label-free electrochemiluminescence (ECL) immunosensor was fabricated for the detection of β-2-microglobulin (β2M) based on a gold nanoparticle-doped@carbon nano-onion chitosan nanocomposite modified cadmium selenide quantum dot screen-printed electrode (QDs-SPE/AuNPs@CNOs-CS) for the first time.

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