Electrocardiographic imaging (ECGI): a new noninvasive imaging modality for cardiac electrophysiology and arrhythmia

2006 ◽  
Author(s):  
Yoram Rudy
2017 ◽  
Vol 9 ◽  
pp. 117917211668607 ◽  
Author(s):  
Jeffrey Ma ◽  
Ria Desai ◽  
Peter Nesper ◽  
Manjot Gill ◽  
Amani Fawzi ◽  
...  

Optical coherence tomographic angiography (OCTA) is emerging as a rapid, noninvasive imaging modality that can provide detailed structural and flow information on retinal and choroidal vasculature. This review contains an introduction of OCTA and summarizes the studies to date on OCTA imaging in age-related macular degeneration.


Circulation ◽  
2000 ◽  
Vol 102 (17) ◽  
pp. 2152-2158 ◽  
Author(s):  
John E. Burnes ◽  
Bruno Taccardi ◽  
Yoram Rudy

2016 ◽  
Vol 2016 ◽  
pp. 1-4
Author(s):  
Takayuki Shimizu ◽  
Daisuke Koike ◽  
Yukihiro Nomura ◽  
Kenji Ooe

Colonic angiodysplasia (AD) with bleeding as a comorbidity in the aging population is being increasingly reported. However, to our knowledge, there is no report on colonic AD accompanied by a huge hematoma. Herein, we report a case of colonic AD with a huge submucosal hematoma. A 75-year-old man with sudden melena was referred to our hospital. Helical computed tomographic angiography (CTA) revealed bleeding from the sigmoid colon. Additionally, colonoscopy showed a huge submucosal hematoma with bleeding in the sigmoid colon. As endoscopic hemostasis was difficult, sigmoidectomy was performed. The pathological diagnosis was colonic AD. The present case indicates that colonic AD should be considered in the differential diagnosis for melena. In addition, the case shows that helical CTA, which is a noninvasive imaging modality, is useful for the diagnosis of colonic AD and is as effective as colonoscopy and angiography for diagnosis.


Hearts ◽  
2021 ◽  
Vol 2 (3) ◽  
pp. 331-349
Author(s):  
Christopher M. Andrews ◽  
Gautam K. Singh ◽  
Yoram Rudy

Despite the success of cardiac resynchronization therapy (CRT) for treating heart failure (HF), the rate of nonresponders remains 30%. Improvements to CRT require understanding of reverse remodeling and the relationship between electrical and mechanical measures of synchrony. The objective was to utilize electrocardiographic imaging (ECGI, a method for noninvasive cardiac electrophysiology mapping) and speckle tracking echocardiography (STE) to study the physiology of HF and reverse remodeling induced by CRT. We imaged 30 patients (63% male, mean age 63.7 years) longitudinally using ECGI and STE. We quantified CRT-induced remodeling of electromechanical parameters and evaluated a novel index, the electromechanical delay (EMD, the delay from activation to peak contraction). We also measured dyssynchrony using ECGI and STE and compared their effectiveness for predicting response to CRT. EMD values were elevated in HF patients compared to controls. However, the EMD values were dependent on the activation sequence (CRT-paced vs. un-paced), indicating that the EMD is not intrinsic to the local tissue, but is influenced by factors such as opposing wall contractions. After 6 months of CRT, patients had increased contraction in native rhythm compared to baseline pre-CRT (baseline: −8.55%, 6 months: −10.14%, p = 0.008). They also had prolonged repolarization at the location of the LV pacing lead. The pre-CRT delay between mean lateral LV and RV electrical activation time was the best predictor of beneficial reduction in LV end systolic volume by CRT (Spearman’s Rho: −0.722, p < 0.001); it outperformed mechanical indices and 12-lead ECG criteria. HF patients have abnormal EMD. The EMD depends upon the activation sequence and is not predictive of response to CRT. ECGI-measured LV activation delay is an effective index for CRT patient selection. CRT causes persistent improvements in contractile function.


Sensors ◽  
2020 ◽  
Vol 20 (11) ◽  
pp. 3131 ◽  
Author(s):  
Raúl Caulier-Cisterna ◽  
Margarita Sanromán-Junquera ◽  
Sergio Muñoz-Romero ◽  
Manuel Blanco-Velasco ◽  
Rebeca Goya-Esteban ◽  
...  

During the last years, Electrocardiographic Imaging (ECGI) has emerged as a powerful and promising clinical tool to support cardiologists. Starting from a plurality of potential measurements on the torso, ECGI yields a noninvasive estimation of their causing potentials on the epicardium. This unprecedented amount of measured cardiac signals needs to be conditioned and adapted to current knowledge and methods in cardiac electrophysiology in order to maximize its support to the clinical practice. In this setting, many cardiac indices are defined in terms of the so-called bipolar electrograms, which correspond with differential potentials between two spatially close potential measurements. Our aim was to contribute to the usefulness of ECGI recordings in the current knowledge and methods of cardiac electrophysiology. For this purpose, we first analyzed the basic stages of conventional cardiac signal processing and scrutinized the implications of the spatial-temporal nature of signals in ECGI scenarios. Specifically, the stages of baseline wander removal, low-pass filtering, and beat segmentation and synchronization were considered. We also aimed to establish a mathematical operator to provide suitable bipolar electrograms from the ECGI-estimated epicardium potentials. Results were obtained on data from an infarction patient and from a healthy subject. First, the low-frequency and high-frequency noises are shown to be non-independently distributed in the ECGI-estimated recordings due to their spatial dimension. Second, bipolar electrograms are better estimated when using the criterion of the maximum-amplitude difference between spatial neighbors, but also a temporal delay in discrete time of about 40 samples has to be included to obtain the usual morphology in clinical bipolar electrograms from catheters. We conclude that spatial-temporal digital signal processing and bipolar electrograms can pave the way towards the usefulness of ECGI recordings in the cardiological clinical practice. The companion paper is devoted to analyzing clinical indices obtained from ECGI epicardial electrograms measuring waveform variability and repolarization tissue properties.


Sensors ◽  
2020 ◽  
Vol 20 (11) ◽  
pp. 3070 ◽  
Author(s):  
Raúl Caulier-Cisterna ◽  
Manuel Blanco-Velasco ◽  
Rebeca Goya-Esteban ◽  
Sergio Muñoz-Romero ◽  
Margarita Sanromán-Junquera ◽  
...  

During the last years, attention and controversy have been present for the first commercially available equipment being used in Electrocardiographic Imaging (ECGI), a new cardiac diagnostic tool which opens up a new field of diagnostic possibilities. Previous knowledge and criteria of cardiologists using intracardiac Electrograms (EGM) should be revisited from the newly available spatial–temporal potentials, and digital signal processing should be readapted to this new data structure. Aiming to contribute to the usefulness of ECGI recordings in the current knowledge and methods of cardiac electrophysiology, we previously presented two results: First, spatial consistency can be observed even for very basic cardiac signal processing stages (such as baseline wander and low-pass filtering); second, useful bipolar EGMs can be obtained by a digital processing operator searching for the maximum amplitude and including a time delay. In addition, this work aims to demonstrate the functionality of ECGI for cardiac electrophysiology from a twofold view, namely, through the analysis of the EGM waveforms, and by studying the ventricular repolarization properties. The former is scrutinized in terms of the clustering properties of the unipolar an bipolar EGM waveforms, in control and myocardial infarction subjects, and the latter is analyzed using the properties of T-wave alternans (TWA) in control and in Long-QT syndrome (LQTS) example subjects. Clustered regions of the EGMs were spatially consistent and congruent with the presence of infarcted tissue in unipolar EGMs, and bipolar EGMs with adequate signal processing operators hold this consistency and yielded a larger, yet moderate, number of spatial–temporal regions. TWA was not present in control compared with an LQTS subject in terms of the estimated alternans amplitude from the unipolar EGMs, however, higher spatial–temporal variation was present in LQTS torso and epicardium measurements, which was consistent through three different methods of alternans estimation. We conclude that spatial–temporal analysis of EGMs in ECGI will pave the way towards enhanced usefulness in the clinical practice, so that atomic signal processing approach should be conveniently revisited to be able to deal with the great amount of information that ECGI conveys for the clinician.


2019 ◽  
Vol 10 (2) ◽  
pp. 66-69
Author(s):  
Jawhar Lal Singha ◽  
Sami Ahmad ◽  
Nadim Ahmed ◽  
SM Zulker Nayeem ◽  
Ferdoush Rayhan ◽  
...  

Introduction: 360° endoanal ultrasound (EAUS) has become an effective imaging tool to diagnose anal fistulas for last three decades. Objectives: To assess the diagnostic accuracy of 360° endoanal ultrasound imaging comparing pre and peroperative diagnosis in anal fistulas. Methods: Between Jauary 2015 and June 2018, 240 patients with clinical anal fistula underwent endoanal sonographic assessment using a 360° endoanal transducer (7–15 MHz The sonographic findings, including the fistulas and other inflammatory lesions, were correlated with surgical results. The types of fistulas on endoanal sonography based on classification of Park and the internal opening of the fistula, both pre and peroperative, were compared to those of other studies. Results: The 240 patients studied included 165 male and 75 female patients. Endoanal sonography was able to show and track hypoechoic lesions, their locations, and internal openings of the fistulas. Compared with surgical results, endoanal sonography had sensitivity of 94.6%, specificity of 100%, and accuracy of 94.1% for the diagnosis of perianal fistulas. Also, endoanal sonography had accuracy of 86.1% for determining fistula types based on the Parks classification and 92.8% for identifying internal openings of the fistulas. Conclusions: Endoanal ultrasound is an accurate and noninvasive imaging modality for evaluation of fistulas. It is a very useful tool for preoperative management and surgical planning by providing precise and detailed information on fistulas. J Shaheed Suhrawardy Med Coll, December 2018, Vol.10(2); 66-69


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