High-sensitivity and cost-effective system for infrared imaging of concealed objects in dynamic mode

2005 ◽  
Author(s):  
E. Gordiyenko ◽  
V. Yefremenko ◽  
J. Pearson ◽  
S. D. Bader ◽  
V. Novosad
Keyword(s):  
Infrared Imaging ◽  
High Sensitivity ◽  
Cost Effective ◽  
Dynamic Mode ◽  
Effective System

Extended Routine Follow-up of Primary Uncomplicated Hip and Knee Arthroplasty is not Necessary

2019 ◽  
Vol 13 (1) ◽  
pp. 266-271
Author(s):  
Georgina Kakra Wartemberg ◽  
Thomas Goff ◽  
Simon Jones ◽  
James Newman
Keyword(s):  
Aseptic Loosening ◽  
Revision Surgery ◽  
Revision Arthroplasty ◽  
Cost Effective ◽  
Face To Face ◽  
Primary Surgery ◽  
Effective System ◽  
Knee Revision Surgery ◽  
Knee Revision

Aims: To create a more effective system to identify patients in need of revision surgery. Background: There are over 160,000 total hip and knee replacements performed per year in England and Wales. Currently, most trusts review patients for up to 10 years or more. When we consider the cost of prolonged reviews, we cannot justify the expenditure within a limited budget. Study Design & Methods: We reviewed all patients' notes that underwent primary hip and knee revision surgery at our institution, noting age, gender, symptoms at presentation, referral source, details of the surgery, reason for revision and follow up history from primary surgery. Results: There were 145 revision arthroplasties (60 THR and 85 TKR) that met our inclusion criteria. Within the hip arthroplasty group, indications for revision included aseptic loosening (37), dislocation (10), and infection (3), periprosthetic fracture, acetabular liner wear and implant failure. All thirty-seven patients with aseptic loosening presented with pain. Twenty-five were referred from general practice with new symptoms. The remaining were clinic follow-ups. The most common reason for knee revision was aseptic loosening (37), followed by infection (21) and then progressive osteoarthritis (8). Most were referred from GP as a new referral or were clinic follow-ups. All patients were symptomatic. Conclusion: All the patients that underwent revision arthroplasty were symptomatic. Rather than yearly follow up, we recommend a cost-effective system. We are implementing a 'non face-to-face' system. Patients would be directly sent a questionnaire and x-ray form. The radiographs and forms will be reviewed by an experienced arthroplasty surgeon. The concerning cases will be seen urgently in a face-to-face clinic.

scholarly journals Multiplexed detection of SARS-CoV-2 and other respiratory infections in high throughput by SARSeq

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Ramesh Yelagandula ◽  
◽  
Aleksandr Bykov ◽  
Alexander Vogt ◽  
Robert Heinen ◽  
...  
Keyword(s):  
Influenza A ◽  
Respiratory Infections ◽  
High Sensitivity ◽  
Cost Effective ◽  
Massively Parallel ◽  
Rt Pcr ◽  
Viral Spread ◽  
Saliva Analysis ◽  
Double Blinded ◽  
Generation Sequencing

AbstractThe COVID-19 pandemic has demonstrated the need for massively-parallel, cost-effective tests monitoring viral spread. Here we present SARSeq, saliva analysis by RNA sequencing, a method to detect SARS-CoV-2 and other respiratory viruses on tens of thousands of samples in parallel. SARSeq relies on next generation sequencing of multiple amplicons generated in a multiplexed RT-PCR reaction. Two-dimensional, unique dual indexing, using four indices per sample, enables unambiguous and scalable assignment of reads to individual samples. We calibrate SARSeq on SARS-CoV-2 synthetic RNA, virions, and hundreds of human samples of various types. Robustness and sensitivity were virtually identical to quantitative RT-PCR. Double-blinded benchmarking to gold standard quantitative-RT-PCR performed by human diagnostics laboratories confirms this high sensitivity. SARSeq can be used to detect Influenza A and B viruses and human rhinovirus in parallel, and can be expanded for detection of other pathogens. Thus, SARSeq is ideally suited for differential diagnostic of infections during a pandemic.

scholarly journals A two-stage amplified PZT sensor for monitoring lung and heart sounds in discharged pneumonia patients

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Hongbin Chen ◽  
Shuai Yu ◽  
Haiyang Liu ◽  
Jie Liu ◽  
Yongguang Xiao ◽  
...  
Keyword(s):  
High Sensitivity ◽  
Cost Effective ◽  
High Ratio ◽  
Heart Sounds ◽  
Two Stage ◽  
Diagnosis And Prognosis ◽  
Sensor Device ◽  
Cost Effective Alternative ◽  
A Charge ◽  
Highly Sensitive Detection

AbstractAssessment of lung and heart states is of critical importance for patients with pneumonia. In this study, we present a small-sized and ultrasensitive accelerometer for continuous monitoring of lung and heart sounds to evaluate the lung and heart states of patients. Based on two-stage amplification, which consists of an asymmetric gapped cantilever and a charge amplifier, our accelerometer exhibited an extremely high ratio of sensitivity to noise compared with conventional structures. Our sensor achieves a high sensitivity of 9.2 V/g at frequencies less than 1000 Hz, making it suitable to use to monitor weak physiological signals, including heart and lung sounds. For the first time, lung injury, heart injury, and both lung and heart injuries in discharged pneumonia patients were revealed by our sensor device. Our sound sensor also successfully tracked the recovery course of the discharged pneumonia patients. Over time, the lung and heart states of the patients gradually improved after discharge. Our observations were in good agreement with clinical reports. Compared with conventional medical instruments, our sensor device provides rapid and highly sensitive detection of lung and heart sounds, which greatly helps in the evaluation of lung and heart states of pneumonia patients. This sensor provides a cost-effective alternative approach to the diagnosis and prognosis of pneumonia and has the potential for clinical and home-use health monitoring.

scholarly journals Compliance as a Cost-Effective System of Interaction Between Business and Government

2021 ◽  
Author(s):  
Nikolay I. Dorogov ◽  
Ivan A. Kapitonov ◽  
Nazygul T. Batyrova
Keyword(s):  
Cost Effective ◽  
Effective System

Hardware Support for Cost-Effective System-Level Protection in Multi-core SoCs

2015 ◽  
Author(s):  
George Kornaros ◽  
Ioannis Christoforakis ◽  
Othon Tomoutzoglou ◽  
Dimitrios Bakoyiannis ◽  
Kallia Vazakopoulou ◽  
...  
Keyword(s):  
Cost Effective ◽  
System Level ◽  
Hardware Support ◽  
Effective System

Flexible Fibrous Piezo-Electric Sensor on Printed Silver Electrode

2014 ◽  
Vol 1685 ◽  
Author(s):  
Ho Yeon Son ◽  
Yoon Sung Nam ◽  
Woo Soo Kim
Keyword(s):  
Vinylidene Fluoride ◽  
Silver Nanowires ◽  
High Sensitivity ◽  
Cost Effective ◽  
Piezoelectric Sensor ◽  
Piezoelectric Sensors ◽  
Mechanical Stimuli ◽  
Aligned Arrays ◽  
Poly Vinylidene Fluoride ◽  
Facile Fabrication

ABSTRACTHere we introduce a facile method to fabricate a flexible piezoelectric sensor using one-dimensional (1-D) piezoelectric poly(vinylidene fluoride) (PVDF) nanofibers directly produced onto flexible printed electrodes by electro-spinning without an additional poling process. The flexible silver electrodes are fabricated on polyethylene terephthalate (PET) using silver nanowires by easy and cost-effective spraying deposition. The electrospun PVDF nanofibers have uniaxially aligned arrays on the electrodes by using a rotating collector. The fabricated PVDF piezoelectric sensors demonstrate the piezoelectric responses with repeated mechanical stimuli with good flexibility and high sensitivity. We expect that the facile fabrication of PVDF piezoelectric sensors on flexible printed electrodes can be usefully exploited to integrate the piezoelectric sensors into flexible and stretchable functional electronic devices.

scholarly journals MWCNT Devices Fabricated by Dielectrophoresis: Study of Their Electrical Behavior Related to Deposited Nanotube Amount for Gas Sensing Applications

2015 ◽  
Vol 10 (1) ◽  
pp. 13-20
Author(s):  
Elisabete Galeazzo ◽  
Marcos C. Moraes ◽  
Henrique E. M. Peres ◽  
Michel O. S. Dantas ◽  
Victor G. C. Lobo ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Gas Sensing ◽  
High Sensitivity ◽  
Cost Effective ◽  
Adsorbed Water ◽  
Fast Response ◽  
Process Time ◽  
Electrical Behavior ◽  
Glass Substrates ◽  
Sensing Applications

Intensive research has been focused on investigating new sensing materials, such as carbon nanotubes (CNT) because of their promising characteristics. However, there are challenges related to their application in commercial devices such as sensitivity, compatibility, and complexity of miniaturization, among others. We report the study of the electrical behavior of devices composed by multi-walled carbon nanotubes (MWCNT) deposited between aluminum electrodes on glass substrates by means of dielectrophoresis (DEP), which is a simple and cost-effective method. The devices were fabricated by varying the DEP process time. Remarkable changes in their electric resistance were noticed depending on the MWCNT quantities deposited. Other electrical properties of devices such as high sensitivity, fast response time and stability are also characterized in humid environment. A humidity sensing mechanism is proposed on the basis of charge transfer between adsorbed water molecules and the MWNTC surface or between water and the glass surface.

scholarly journals A New Rapid and Cost-Effective Method for Detection of Phages, ICEs and Virulence Factors Encoded by Streptococcus pyogenes

2011 ◽  
Vol 60 (3) ◽  
pp. 187-201 ◽  
Author(s):  
ANNA L. BOREK ◽  
JOANNA WILEMSKA ◽  
RADOSŁAW IZDEBSKI ◽  
WALERIA HRYNIEWICZ ◽  
IZABELA SITKIEWICZ
Keyword(s):  
Virulence Factors ◽  
Streptococcus Pyogenes ◽  
Group A Streptococcus ◽  
Cost Effective ◽  
Cost Effective Method ◽  
Effective System ◽  
Genes Encoding ◽  
Invasive Infections ◽  
Integration Sites ◽  
Severity Of The Disease

Streptococcus pyogenes (group A Streptococcus, GAS) is a human pathogen that causes diseases of various intensity, from mild strep throat to life threatening invasive infections and postinfectional sequelae. S. pyogenes encodes multiple, often phage encoded, virulence factors and their presence is related to severity of the disease. Acquisition of mobile genetic elements, carrying virulence factors, as phages or ICEs (integrative and cojugative elements) has been shown previously to promote selection of virulent clones. We designed the system of eight low volume multi- and one singleplex PCR reactions to detect genes encoding twenty virulence factors (spd3, sdc, sdaB, sdaD, speB, spyCEP, scpA, mac, sic, speL, K, M, C, I, A, H, G, J, smeZ and ssa) and twenty one phage and ICE integration sites described so far for S. pyogenes. Classification of strains based on the phage and virulence factors absence or presence, correlates with PFGE MLST and emm typing results. We developed a novel, fast and cost effective system that can be used to detect GAS virulence factors. Moreover, this system may become an alternative and effective system to differentiate between GAS strains.

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