Miniature fiber optic sensor based on fluorescence energy transfer

1992 ◽  
Author(s):  
David L. Meadows ◽  
Jerome S. Schultz
Keyword(s):  
Energy Transfer ◽  
Fiber Optic ◽  
Fiber Optic Sensor ◽  
Fluorescence Energy Transfer ◽  
Optic Sensor ◽  
Fluorescence Energy

Chromophore Dynamics in Sol-Gel Glasses and Xerogel Clad Fiber Optic Sensors

1994 ◽  
Vol 346 ◽  
Author(s):  
Drew L'Esperance ◽  
Clarice A. Browne ◽  
Eric L. Chronister
Keyword(s):  
Energy Transfer ◽  
Fiber Optic ◽  
Rotational Diffusion ◽  
Sol Gel ◽  
Fiber Optic Sensors ◽  
Fiber Optic Sensor ◽  
Time Resolved ◽  
Optic Sensor ◽  
Sensor Device ◽  
Gel Glasses

ABSTRACTTime-resolved depolarization measurements are used to investigate rotational diffusion and optical energy transfer dynamics of chromophores incorporated into silica and aluminosilica solutions, gels, and glasses. The use of an organically doped sol-gel clad waveguide as a novel intrinsic fiber optic sensor device is also demonstrated, and advantages of time-resolved detection of the fiber optic sensor are illustrated.

Fiber optic biosensor for Co(II) and Cu(II) based on fluorescence energy transfer with an enzyme transducer

1996 ◽  
Vol 11 (6-7) ◽  
pp. 557-564 ◽  
Author(s):  
Richard B. Thompson ◽  
Ge Zhengfang ◽  
Marcia Patchan ◽  
Huang Chih-Chin ◽  
Carol A. Fierke
Keyword(s):  
Energy Transfer ◽  
Fiber Optic ◽  
Fluorescence Energy Transfer ◽  
Fluorescence Energy

Fiber optic immunochemical sensor for continuous, reversible measurement of phenytoin.

1988 ◽  
Vol 34 (7) ◽  
pp. 1417-1421 ◽  
Author(s):  
F P Anderson ◽  
W G Miller
Keyword(s):  
Response Time ◽  
Fiber Optic ◽  
Anticonvulsant Drug ◽  
Fiber Optic Sensor ◽  
Fluorescence Signal ◽  
Dialysis Tubing ◽  
Optic Sensor ◽  
Equilibrium Response ◽  
Texas Red ◽  
Fluorescence Energy

Abstract This fiber optic sensor, based on a homogeneous fluorescence energy-transfer immunoassay, operates in a continuous, reversible manner to quantify the anticonvulsant drug phenytoin. B-Phycoerythrin-phenytoin and Texas Red-labeled antibody to phenytoin were sealed inside a short length of cellulose dialysis tubing, which was cemented to the distal end of an optical fiber. When the sensor was alternately placed into solutions with various concentrations of free phenytoin, the drug crossed the dialysis membrane and displaced a fraction of the B-phycoerythrin-phenytoin from the antibody. The resulting change in fluorescence signal was measured with a fiber optic fluorometer. A typical competitive-binding calibration curve was seen between 5 and 500 mumol of phenytoin per liter. Equilibrium response time ranged from 5 to 30 min for different sensors. Replicate equilibrium measurements with one sensor, alternated eight times between two solutions of phenytoin, gave a CV of 2.1% (n = 16) at 0 mumol/L and 2.4% (n = 13) at 100 mumol/L. A reversible immunochemical sensor can be made that has a response time suitable for continuous concentration measurements.

Determination of multiple analytes using a fiber optic biosensor based on fluorescence energy transfer

1996 ◽  
Author(s):  
Richard B. Thompson ◽  
Zhengfang Ge ◽  
Marcia W. Patchan ◽  
Carol A. Fierke ◽  
Keith A. McCall ◽  
...  
Keyword(s):  
Energy Transfer ◽  
Fiber Optic ◽  
Fluorescence Energy Transfer ◽  
Multiple Analytes ◽  
Fluorescence Energy

Fiber Optic Sensor for Measuring Rotation

2011 ◽  
Vol 14 (4) ◽  
pp. 66-72 ◽  
Author(s):  
S.M. Al-Hilly ◽  
◽  
Z. E. Khaleel ◽  
A.F. Alrubaye ◽  
◽  
...  
Keyword(s):  
Fiber Optic ◽  
Fiber Optic Sensor ◽  
Optic Sensor
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