Parallel fluorescence correlation spectroscopy with a fully integrated single photon 2x2 detector array made with conventional CMOS technology

2004 ◽  
Author(s):  
Alexandre Serov ◽  
Michael Goesch ◽  
Alexis Rochas ◽  
Hans Blom ◽  
Tiemo Anhut ◽  
...  
Keyword(s):  
Fluorescence Correlation Spectroscopy ◽  
Single Photon ◽  
Cmos Technology ◽  
Correlation Spectroscopy ◽  
Detector Array ◽  
Fully Integrated ◽  
Fluorescence Correlation

scholarly journals Fluorescence correlation spectroscopy with visible-wavelength superconducting nanowire single-photon detector

2014 ◽  
Vol 22 (23) ◽  
pp. 28783 ◽  
Author(s):  
Taro Yamashita ◽  
Dengkuan Liu ◽  
Shigehito Miki ◽  
Johtaro Yamamoto ◽  
Tokuko Haraguchi ◽  
...  
Keyword(s):  
Fluorescence Correlation Spectroscopy ◽  
Single Photon ◽  
Correlation Spectroscopy ◽  
Photon Detector ◽  
Single Photon Detector ◽  
Fluorescence Correlation ◽  
Visible Wavelength ◽  
Superconducting Nanowire

scholarly journals Interferometric Fluorescent Cross Correlation Spectroscopy

2019 ◽  
Author(s):  
Ipsita Saha ◽  
Saveez Saffarian
Keyword(s):  
Quantum Dots ◽  
Fluorescence Correlation Spectroscopy ◽  
Cross Correlation ◽  
Single Photon ◽  
Theoretical Framework ◽  
Correlation Spectroscopy ◽  
Aqueous Samples ◽  
Cellular Membranes ◽  
Fluorescence Correlation ◽  
Fluorescent Molecules

AbstractWe present a method utilizing single photon interference and fluorescence correlation spectroscopy (FCS) to simultaneously measure transport of fluorescent molecules within aqueous samples. Our method, within seconds, measures transport in thousands of homogenous voxels (100 nm)3 and eliminates photo-physical artifacts associated with blinking of fluorescent molecules. A comprehensive theoretical framework is presented and validated by measuring transport of quantum dots, associated with VSV-G receptor along cellular membranes as well as within viscous gels.

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