Optical fiber biosensor based on localized surface plasmon resonance in gold nanoparticles

2004 ◽  
Author(s):  
Kotaro Kajikawa ◽  
Keita Mitsui
Keyword(s):  
Gold Nanoparticles ◽  
Surface Plasmon Resonance ◽  
Optical Fiber ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Localized Surface Plasmon Resonance ◽  
Localized Surface Plasmon

scholarly journals Design and validation of fiber optic localized surface plasmon resonance sensor for thyroglobulin immunoassay with high sensitivity and rapid detection

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Hyeong-Min Kim ◽  
Dae Hong Jeong ◽  
Ho-Young Lee ◽  
Jae-Hyoung Park ◽  
Seung-Ki Lee
Keyword(s):  
Surface Plasmon Resonance ◽  
Optical Fiber ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Localized Surface Plasmon Resonance ◽  
Optical Fiber Sensor ◽  
Fiber Sensor ◽  
Localized Surface Plasmon ◽  
Simple Method ◽  
Resonance Sensor

AbstractA simple optical fiber sensor based on localized surface plasmon resonance was constructed for direct and rapid measurement of thyroglobulin (Tg). Specific tests for Tg in patients that have undergone thyroidectomy are limited because of insufficient sensitivity, complicated procedures, and in some cases, a long time to yield a result. A sensitive, fast, and simple method is necessary to relieve the psychological and physical burden of the patient. Various concentrations of Tg were measured in a microfluidic channel using an optical fiber sensor with gold nanoparticles. The sensor chip has a detection limit of 93.11 fg/mL with no specificity for other antigens. The potential applicability of the Tg sensing system was evaluated using arbitrary samples containing specific concentrations of Tg. Finally, the sensor can be employed to detect Tg in the patient’s serum, with a good correlation when compared with the commercial kit.

Sign in / Sign up

Export Citation Format

Share Document