Soft-tissue contrast resolution within the head of human cadaver by means of flat-detector-based cone-beam CT

Author(s):  
Jens Wiegert ◽  
Matthias Bertram ◽  
Dirk Schaefer ◽  
Norbert Conrads ◽  
Niels Noordhoek ◽  
...  
2020 ◽  
Vol 70 ◽  
pp. 1-9 ◽  
Author(s):  
Sanghoon Cho ◽  
Sunho Lim ◽  
Changhwan Kim ◽  
Sunhee Wi ◽  
Taejin Kwon ◽  
...  

2007 ◽  
Vol 34 (6Part21) ◽  
pp. 2607-2608
Author(s):  
B Reitz ◽  
O Gayou ◽  
M Johnson ◽  
D Parda ◽  
M Miften

2010 ◽  
Vol 10 (2) ◽  
pp. 121-136 ◽  
Author(s):  
Winky Wing Ki Fung ◽  
Vincent Wing Cheung Wu

AbstractThe sharp dose gradients in intensity-modulated radiation therapy increase the treatment sensitivity to various inter- and intra-fractional uncertainties, in which a slight anatomical change may greatly alter the actual dose delivered. Image-guided radiotherapy refers to the use of advanced imaging techniques to precisely track and correct these patient-specific variations in routine treatment. It can also monitor organ changes during a radiotherapy course. Currently, image-guided radiotherapy using computed tomography has gained much popularity in radiotherapy verification as it provides volumetric images with soft-tissue contrast for on-line tracking of tumour. This article reviews four types of computed tomography-based image guidance systems and their working principles. The system characteristics and clinical applications of the helical, megavoltage, computed tomography, and kilovoltage, cone-beam, computed tomography systems are discussed, given that they are currently the most commonly used systems for radiotherapy verification. This article also focuses on the recent techniques of soft-tissue contrast enhancement, digital tomosynthesis, four-dimensional fluoroscopic image guidance, and kilovoltage/megavoltage, in-line cone-beam imaging. These evolving systems are expected to take over the conventional two-dimensional verification system in the near future and provide the basis for implementing adaptive radiotherapy.


2007 ◽  
Vol 6 (03) ◽  
pp. 173-178 ◽  
Author(s):  
M. Broderick ◽  
G. Menezes ◽  
M. Leech ◽  
M. Coffey ◽  
R. Appleyard

AbstractAs more and more patients are planned in 3D, the need to verify their position and treatment in 3D also becomes apparent. Megavoltage (MV) and kilovoltage (KV) cone beam computed tomography (CBCT) provide 3D verification of patient position. However, the soft tissue contrast and thus the accuracy of delineation is superior with KV CT imaging. CBCT in conjunction with energy fluence maps from electronic portal imaging devices (EPIDs) could theoretically be used to verify the dose delivered. In this instance, a cross calibration between the KV CBCT and the EPID would be required which would not be necessary with MV CBCT. Adaptive planning with CBCT poses similar challenges for both KV and MV CBCT. Although KV CBCT can produce images with Hounsfield units (HUs) comparable with conventional CT in homogenous phantoms there are large discrepancies in inhomogeneous mediums. If the cupping artefact is corrected for in MV CBCT, the HU values can compare well with KV CBCT for homogenous media. However, advances need to be made to achieve a lower patient dose with MV CBCT. At present, the lower dose required for KV CBCT allows for more frequent imaging and better image quality.


Cancers ◽  
2021 ◽  
Vol 13 (17) ◽  
pp. 4377
Author(s):  
Chiara Romei ◽  
Salvatore Claudio Fanni ◽  
Federica Volpi ◽  
Alessio Milazzo ◽  
Caterina Aida D’Amore ◽  
...  

Malignant pleural mesothelioma is a rare neoplasm with poor prognosis. CT is the first imaging technique used for diagnosis, staging, and assessment of therapy response. Although, CT has intrinsic limitations due to low soft tissue contrast and the current staging system as well as criteria for evaluating response, it does not consider the complex growth pattern of this tumor. Computer-based methods have proven their potentiality in diagnosis, staging, prognosis, and assessment of therapy response; moreover, computer-based methods can make feasible tasks like segmentation that would otherwise be impracticable. MRI, thanks to its high soft tissue contrast evaluation of contrast enhancement and through diffusion-weighted-images, could replace CT in many clinical settings.


2020 ◽  
Vol 47 ◽  
pp. 101743
Author(s):  
Amanda Farias Gomes ◽  
Debora Duarte Moreira ◽  
Mariana Fabbro Zanon ◽  
Francisco Carlos Groppo ◽  
Francisco Haiter-Neto ◽  
...  

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