scholarly journals Radiation-induced synergistic effects of athermal and thermal mechanisms on erosion and surface evolution of advanced electrode and condenser optics materials

2004 ◽  
Author(s):  
Jean Paul Allain ◽  
Ahmed Hassanein ◽  
Tatiana Burtseva ◽  
Abdellatif Yacout ◽  
Zinetulla Insepov ◽  
...  
Keyword(s):  
Synergistic Effects ◽  
Surface Evolution ◽  
Radiation Induced

scholarly journals Ion Implantation At Elevated Temperatures

1985 ◽  
Vol 51 ◽  
Author(s):  
Nghi Q. Lam ◽  
Gary K. Leaf
Keyword(s):  
Present Model ◽  
Elevated Temperatures ◽  
Synergistic Effects ◽  
Concentration Profiles ◽  
Enhanced Diffusion ◽  
Preferential Sputtering ◽  
Radiation Enhanced Diffusion ◽  
Spatial Redistribution ◽  
Radiation Induced ◽  
Effects Of Radiation

ABSTRACTA kinetic model has been developed to investigate the synergistic effects of radiation-enhanced diffusion, radiation-induced segregation and preferential sputtering on the spatial redistribution of implanted solutes during implantation at elevated temperatures. Sample calculations were performed for Al+ and Si+ ions implanted into Ni. With the present model, the influence of various implantation parameters on the evolution of implant concentration profiles could be examined in detail.

scholarly journals Why Concurrent CDDP and Radiotherapy Has Synergistic Antitumor Effects: A Review of In Vitro Experimental and Clinical-Based Studies

2021 ◽  
Vol 22 (6) ◽  
pp. 3140
Author(s):  
Shinsuke Nagasawa ◽  
Junko Takahashi ◽  
Gen Suzuki ◽  
Yamazaki Hideya ◽  
Kei Yamada
Keyword(s):  
Dna Damage ◽  
Synergistic Effect ◽  
Anticancer Drugs ◽  
Synergistic Effects ◽  
Cancer Therapies ◽  
Antitumor Effects ◽  
Combined Use ◽  
Cell Components ◽  
Radiation Induced

Chemo-radiotherapy, which combines chemotherapy with radiotherapy, has been clinically practiced since the 1970s, and various anticancer drugs have been shown to have a synergistic effect when used in combination with radiotherapy. In particular, cisplatin (CDDP), which is often the cornerstone of multi-drug combination cancer therapies, is highly versatile and frequently used in combination with radiotherapy for the treatment of many cancers. Therefore, the mechanisms underlying the synergistic effect of CDDP and radiotherapy have been widely investigated, although no definitive conclusions have been reached. We present a review of the combined use of CDDP and radiotherapy, including the latest findings, and propose a mechanism that could explain their synergistic effects. Our hypothesis involves the concepts of overlap and complementation. “Overlap” refers to the overlapping reactions of CDDP and radiation-induced excessive oxidative loading, which lead to accumulating damage to cell components, mostly within the cytoplasm. “Complementation” refers to the complementary functions of CDDP and radiation that lead to DNA damage, primarily in the nucleus. In fact, the two concepts are inseparable, but conceptualizing them separately will help us understand the mechanism underlying the synergism between radiation therapy and other anticancer drugs, and help us to design future radiosensitizers.

Mechanisms and kinetics of ion implantation

1986 ◽  
Vol 1 (2) ◽  
pp. 251-267 ◽  
Author(s):  
Nghi Q. Lam ◽  
Gary K. Leaf
Keyword(s):  
Ion Implantation ◽  
Elevated Temperatures ◽  
Synergistic Effects ◽  
Implantation Rate ◽  
Host Lattice ◽  
Ion Energy ◽  
Enhanced Diffusion ◽  
Preferential Sputtering ◽  
Radiation Enhanced Diffusion ◽  
Radiation Induced

The evolution of the implant distribution during ion implantation at elevated temperatures has been theoretically studied using a comprehensive kinetic model. In the model foreign atoms, implanted into both interstitial and substitutional sites of the host lattice, could interact with implantation-induced point defects and with extended sinks such as the bombarded surface. The synergistic effects of preferential sputtering, radiation-enhanced diffusion, and radiation-induced segregation, as well as the influence of nonuniform defect production, were taken into account. The bombarded surface was allowed to move in either direction, − x or + x, depending on ion energy, i.e., on the competition between the rates of ion deposition and sputtering. The moving surface was accounted for by means of a mathematical technique of immobilizing the boundary. The ion implantation process was cast into a system of five coupled partial differential equations, which could be solved numerically using a suitable technique. Sample calculations were performed for two systems: Si+ and Al+ implantations into Ni. It has been known from previous studies that in irradiated Ni, Si atoms segregate in the same direction as the defect fluxes, whereas Al solutes migrate in the opposite direction. Thus the effects of different segregation mechanisms, as well as the influence of target temperature, ion energy, and implantation rate on the evolution of implant concentrations in time and space, could be examined with the present model.

Mechanisms and Kinetics of Iion Beam-Induced Compositional Modifications

1988 ◽  
Vol 100 ◽  
Author(s):  
N. Q. Lam
Keyword(s):  
Synergistic Effects ◽  
Relative Significance ◽  
Near Surface ◽  
Enhanced Diffusion ◽  
Thermally Activated ◽  
Target Composition ◽  
Radiation Enhanced Diffusion ◽  
Radiation Induced ◽  
The Individual ◽  
Kinetics Of

ABSTRACTNear-surface compositional modification of ion-bombarded alloys results from the dynamic interplay of several atomistic processes. In addition to displacement mixing leading to t randomization of atomic locations, which is dominant at relatively low temperatures, and preferential loss of alloying elements by sputtering, many thermally-activated processes, including radiation-enhanced diffusion, radiation-induced segregation and Gibbsian adsorption, also play important roles. The relative contributions of these processes to the evolution of the target composition profile depends on the target materials and irradiation variables. Although a good understanding of the individual processes has been achieved, information regarding their synergistic effects on alloy surface modification is still limited. In the present article, these processes will be characterized in simple physical terms, and the present understanding of their relative significance and contributions in changing the target composition during ion bombardment will be discussed in view of recent progress in theoretical modeling and experimental study.

Synergistic effects of H2O2 and S2O82− in the gamma radiation induced degradation of congo-red dye: Kinetics and toxicities evaluation

2020 ◽  
Vol 233 ◽  
pp. 115966 ◽  
Author(s):  
Noor S. Shah ◽  
Javed Ali Khan ◽  
Murtaza Sayed ◽  
Zia Ul Haq Khan ◽  
Jibran Iqbal ◽  
...  
Keyword(s):  
Gamma Radiation ◽  
Congo Red ◽  
Synergistic Effects ◽  
Congo Red Dye ◽  
Radiation Induced ◽  
Red Dye
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