Three-dimensional diffuse optical tomography with a priori anatomical information

2003 ◽  
Author(s):  
Murat Guven ◽  
Birsen Yazici ◽  
Xavier Intes ◽  
Britton Chance
2005 ◽  
Vol 50 (12) ◽  
pp. 2837-2858 ◽  
Author(s):  
Murat Guven ◽  
Birsen Yazici ◽  
Xavier Intes ◽  
Britton Chance

2003 ◽  
Author(s):  
Murat Guven ◽  
Birsen Yazici ◽  
Xavier Intes ◽  
Britton Chance

2021 ◽  
Vol 11 (4) ◽  
pp. 1670
Author(s):  
Tetsuya Mimura ◽  
Shinpei Okawa ◽  
Hiroshi Kawaguchi ◽  
Yukari Tanikawa ◽  
Yoko Hoshi

Thyroid cancer is usually diagnosed by ultrasound imaging and fine-needle aspiration biopsy. However, diagnosis of follicular thyroid carcinomas (FTC) is difficult because FTC lacks nuclear atypia and a consensus on histological interpretation. Diffuse optical tomography (DOT) offers the potential to diagnose FTC because it can measure tumor hypoxia, while image reconstruction of the thyroid is still challenging mainly due to the complex anatomical features of the neck. In this study, we attempted to solve this issue by creating a finite element model of the human neck excluding the trachea (a void region). By reconstruction of the absorption coefficients at three wavelengths, 3D tissue oxygen saturation maps of the human thyroid are obtained for the first time by DOT.


2012 ◽  
Vol 17 (12) ◽  
pp. 126009 ◽  
Author(s):  
Kirstin Baum ◽  
Raimo Hartmann ◽  
Tobias Bischoff ◽  
Jan O. Oelerich ◽  
Stephan Finkensieper ◽  
...  

2014 ◽  
Vol 22 (3) ◽  
Author(s):  
Caifang Wang

Abstract.Diffuse optical tomography (DOT) is an optical imaging modality, which provides the spatial distribution of the optical parameters inside a random medium. A propagation back-propagation method named EM-like reconstruction method for stationary DOT problem has been proposed yet. This method is really time consuming. Hence the ordered-subsets (OS) technique for this reconstruction method is studied in this paper. The boundary measurements of DOT are grouped into nonoverlapping and overlapping ordered sequence of subsets with random partition, sequential partition and periodic partition, respectively. The performance of OS methods is compared with the standard EM-like reconstruction method with two-dimensional and three-dimensional numerical experiments. The numerical experiments indicate that reconstruction of nonoverlapping subsets with periodic partition, overlapping subsets with periodic partition and standard EM-like method provide very similar acceptable reconstruction results. However, reconstruction of nonoverlapping subsets with periodic partition spends a minimum of time to get proper results.


2008 ◽  
Vol 27 (6) ◽  
pp. 752-765 ◽  
Author(s):  
G. Boverman ◽  
E.L. Miller ◽  
D.H. Brooks ◽  
D. Isaacson ◽  
Qianqian Fang ◽  
...  

2011 ◽  
Vol 2011 ◽  
pp. 1-13 ◽  
Author(s):  
Michael Ghijsen ◽  
Yuting Lin ◽  
Mitchell Hsing ◽  
Orhan Nalcioglu ◽  
Gultekin Gulsen

Diffuse Optical Tomography (DOT) is an optical imaging modality that has various clinical applications. However, the spatial resolution and quantitative accuracy of DOT is poor due to strong photon scatting in biological tissue. Structurala prioriinformation from another high spatial resolution imaging modality such as Magnetic Resonance Imaging (MRI) has been demonstrated to significantly improve DOT accuracy. In addition, a contrast agent can be used to obtain differential absorption images of the lesion by using dynamic contrast enhanced DOT (DCE-DOT). This produces a relative absorption map that consists of subtracting a reconstructed baseline image from reconstructed images in which optical contrast is included. In this study, we investigated and compared different reconstruction methods and analysis approaches for regular endogenous DOT and DCE-DOT with and without MR anatomicala prioriinformation for arbitrarily-shaped objects. Our phantom and animal studies have shown that superior image quality and higher accuracy can be achieved using DCE-DOT together with MR structurala prioriinformation. Hence, implementation of a combined MRI-DOT system to image ICG enhancement can potentially be a promising tool for breast cancer imaging.


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