Light dosimetry in vivo in interstitial photodynamic therapy of human tumors

1991 ◽  
Author(s):  
Anne M. Reynes ◽  
Simon Diebold ◽  
Dominique Lignon ◽  
Yves Granjon ◽  
Francois H. Guillemin
Keyword(s):  
Photodynamic Therapy ◽  
Human Tumors ◽  
Light Dosimetry ◽  
Interstitial Photodynamic Therapy

In Vivo Light Dosimetry In Interstitial Photodynamic Therapy

1988 ◽  
Author(s):  
I Driver ◽  
J W. Feather ◽  
P R. King ◽  
D Gilson ◽  
D V. Ash ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Light Dosimetry ◽  
Interstitial Photodynamic Therapy

scholarly journals Intra-cavity Photodynamic Therapy for malignant tumors of the paranasal sinuses: An in vivo light dosimetry study

2020 ◽  
Vol 32 ◽  
pp. 101972
Author(s):  
T.E.M. van Doeveren ◽  
R.L.P. van Veen ◽  
F. van den Boom ◽  
I.B. Tan ◽  
W.H. Schreuder ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Paranasal Sinuses ◽  
Malignant Tumors ◽  
Light Dosimetry

scholarly journals MULTIPLE-FIELD INTERSTITIAL PHOTODYNAMIC THERAPY OF SUBCUTANEOUSLY TRANSPLANTED CHOLANGIOCELLULAR CARCINOMA RS-1 IN RATS

2017 ◽  
Vol 39 (2) ◽  
pp. 117-120
Author(s):  
D A Tzerkovsky
Keyword(s):  
Photodynamic Therapy ◽  
Power Density ◽  
Optical Fibers ◽  
Treatment Time ◽  
Cholangiocellular Carcinoma ◽  
Antitumor Efficacy ◽  
Total Power ◽  
Interstitial Photodynamic Therapy ◽  
Multiple Field

The aim of present study was to investigate an antitumor efficacy of multiple-field interstitial photodynamic therapy (iPDT) in vivo. Materials and Methods: The study was performed on 15 white random-bred rats with subcutaneously transplanted cholangiocellular carcinoma RS-1. Chlorine-based photosensitizer (PS) Ce6CPPPS was administered via single injection at a dose of 2.5 mg/kg into the animal’s caudal vein. Photoirradiation (PI) of tumors was carried out 3 h after PS administration using 7 optical fibers SMA-905 with diode laser with 660 ± 5 nm wavelength at exposure doses of 150 and 300 J/cm² with 0.21 W/cm² fluency rate. The total power density was 360 mW and treatment time was 12 and 24 min. Antitumor efficacy of iPDT was assessed by evaluation of necrosis areas and depth of necrosis in experimental tumors. Results: The results have shown that interstitial PI with multi-field low power density enhanced the antitumor effect of PDT in the RS-1 model. Necrosis areas in tumor tissues after PI with exposure doses 150 and 300 J/cm2 24 h and 96 h after treatment were 83.78 ± 4.25 and 100% (p = 0.00074); 56.79 ± 3.24 and 95.46 ± 1.64% (p < 0.00001), respectively. Conclusion: An analysis of the literature data and the results obtained in this study evidence on high effectiveness of the method of multiple-field.

Realtime light dosimetry software tools for interstitial photodynamic therapy of the human prostate

2007 ◽  
Vol 34 (11) ◽  
pp. 4309-4321 ◽  
Author(s):  
Ann Johansson ◽  
Johan Axelsson ◽  
Stefan Andersson-Engels ◽  
Johannes Swartling
Keyword(s):  
Photodynamic Therapy ◽  
Software Tools ◽  
Human Prostate ◽  
Light Dosimetry ◽  
Interstitial Photodynamic Therapy

In vivo light dosimetry during superficial photodynamic therapy

1994 ◽  
Author(s):  
Emma J. Hudson ◽  
Mark R. Stringer ◽  
F. Cairnduff ◽  
Michael A. Smith
Keyword(s):  
Photodynamic Therapy ◽  
Light Dosimetry

scholarly journals In vivo measurement of parameters of dosimetric importance during interstitial photodynamic therapy of thick skin tumors

2006 ◽  
Vol 11 (3) ◽  
pp. 034029 ◽  
Author(s):  
Ann Johansson ◽  
Thomas Johansson ◽  
Marcelo Soto Thompson ◽  
Niels Bendsoe ◽  
Katarina Svanberg ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Skin Tumors ◽  
In Vivo Measurement ◽  
Interstitial Photodynamic Therapy ◽  
Thick Skin
Sign in / Sign up

Export Citation Format

Share Document