Coherent scatter computed tomography: a novel medical imaging technique

Author(s):  
Jens-Peter Schlomka ◽  
Adrian Harding ◽  
Udo van Stevendaal ◽  
Michael Grass ◽  
Geoffrey L. Harding
Author(s):  
H.W. Deckman ◽  
B.F. Flannery ◽  
J.H. Dunsmuir ◽  
K.D' Amico

We have developed a new X-ray microscope which produces complete three dimensional images of samples. The microscope operates by performing X-ray tomography with unprecedented resolution. Tomography is a non-invasive imaging technique that creates maps of the internal structure of samples from measurement of the attenuation of penetrating radiation. As conventionally practiced in medical Computed Tomography (CT), radiologists produce maps of bone and tissue structure in several planar sections that reveal features with 1mm resolution and 1% contrast. Microtomography extends the capability of CT in several ways. First, the resolution which approaches one micron, is one thousand times higher than that of the medical CT. Second, our approach acquires and analyses the data in a panoramic imaging format that directly produces three-dimensional maps in a series of contiguous stacked planes. Typical maps available today consist of three hundred planar sections each containing 512x512 pixels. Finally, and perhaps of most import scientifically, microtomography using a synchrotron X-ray source, allows us to generate maps of individual element.


2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Malte Seemann ◽  
Lennart Bargsten ◽  
Alexander Schlaefer

AbstractDeep learning methods produce promising results when applied to a wide range of medical imaging tasks, including segmentation of artery lumen in computed tomography angiography (CTA) data. However, to perform sufficiently, neural networks have to be trained on large amounts of high quality annotated data. In the realm of medical imaging, annotations are not only quite scarce but also often not entirely reliable. To tackle both challenges, we developed a two-step approach for generating realistic synthetic CTA data for the purpose of data augmentation. In the first step moderately realistic images are generated in a purely numerical fashion. In the second step these images are improved by applying neural domain adaptation. We evaluated the impact of synthetic data on lumen segmentation via convolutional neural networks (CNNs) by comparing resulting performances. Improvements of up to 5% in terms of Dice coefficient and 20% for Hausdorff distance represent a proof of concept that the proposed augmentation procedure can be used to enhance deep learning-based segmentation for artery lumen in CTA images.


2016 ◽  
Vol 23 (2) ◽  
pp. 141-146 ◽  
Author(s):  
Benjamin H. Slovis ◽  
Kaushal H. Shah ◽  
D. Dante Yeh ◽  
Raghu Seethala ◽  
Haytham M. A. Kaafarani ◽  
...  

2021 ◽  
Author(s):  
Eva Chatzinikolaou ◽  
Kleoniki Keklikoglou

Micro-computed tomography (micro-CT) is a high-resolution 3D-imaging technique which is now increasingly applied in biological studies focusing on taxonomy and functional morphology. The creation of virtual representations of specimens can increase availability of otherwise underexploited and inaccessible samples. This protocol aims to standardise micro-CT scanning procedures for embryos and juveniles of the marine gastropod species Hexaplex trunculus.


Author(s):  
Nosaiba Al-Ryalat ◽  
Lna Malkawi ◽  
Ala'a Abu Salhiyeh ◽  
Faisal Abualteen ◽  
Ghaida Abdallah ◽  
...  

Objectives: Our aim was to assess articles published in the field of radiology, nuclear medicine, and medical imaging in 2020, analyzing the linkage of radiology-related topics with coronavirus disease 2019 (COVID-19) through literature mapping, along with a bibliometric analysis for publications. Methods: We performed a search on Web of Science Core Collection database for articles in the field of radiology, nuclear medicine, and medical imaging published in 2020. We analyzed the included articles using VOS viewer software, where we analyzed the co-occurrence of keywords, which represents major topics discussed. Of the resulting topics, literature map created, and linkage analysis done. Results: A total of 24,748 articles were published in the field of radiology, nuclear medicine, and medical imaging in 2020. We found a total of 61,267 keywords, only 78 keywords occurred more than 250 times. COVID-19 had 449 occurrences, 29 links, with a total link strength of 271. MRI was the topic most commonly appearing in 2020 radiology publications, while “computed tomography” has the highest linkage strength with COVID-19, with a linkage strength of 149, representing 54.98% of the total COVID-19 linkage strength, followed by “radiotherapy, and “deep and machine learning”. The top cited paper had a total of 1,687 citations. Nine out of the 10 most cited articles discussed COVID-19 and included “COVID-19” or “coronavirus” in their title, including the top cited paper. Conclusion: While MRI was the topic that dominated, CT had the highest linkage strength with COVID-19 and represent the topic of top cited articles in 2020 radiology publications.


2003 ◽  
Vol 30 (9) ◽  
pp. 2465-2474 ◽  
Author(s):  
U. van Stevendaal ◽  
J.-P. Schlomka ◽  
A. Harding ◽  
M. Grass

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