Monolithic shape memory alloy microgripper for 3D assembly of tissue engineering scaffolds

Author(s):  
Han Zhang ◽  
Yves Bellouard ◽  
Thomas C. Sidler ◽  
Etienne Burdet ◽  
Aun-Neow Poo ◽  
...  
Author(s):  
Hugh Lippincott ◽  
Daniel F. Schmidt

Shape recovery from memory by porous scaffolds for tissue engineering offers easier insertion and self-retention following placement by minimally invasive surgery. Shape memory testing of porous polymer xerogels focuses on the compression cycle and the special aspects of the cycle and equipment used. This contrasts with normal tensile shape memory (SM) testing. In this work a dynamic mechanical analyzer (DMA) was used on small samples to quickly yield measurement of the SM restoration at various stress levels to emulate the forces exerted on the body by a tissue engineering (TE) scaffold returning to its permanent shape. The DMA testing of a hexamethyl diisocyanate trimer crosslinked castor oil (CO) / polycaprolactone (PCL) blend yielded repeated SM with no creep. The porous CO/PCL showed repeated compressive SM at 50% strain with a SM stress-free recovery ratio of 100%. The peak SM recovery work of 6.4 KJ/m3 was measured at 0.5 MPa stress and 6% to 12% strain. In addition to the potential utility of these materials in a tissue engineering setting, the test methods described here are relevant to a broad range of shape memory applications, from medical devices to morphing airframes to self-deploying structures.


2003 ◽  
Vol 112 ◽  
pp. 519-522 ◽  
Author(s):  
W. Cai ◽  
J. X. Zhang ◽  
Y. F. Zheng ◽  
L. C. Zhao

2019 ◽  
Author(s):  
AS Arampatzis ◽  
K Theodoridis ◽  
E Aggelidou ◽  
KN Kontogiannopoulos ◽  
I Tsivintzelis ◽  
...  

2016 ◽  
Vol 19 (2) ◽  
pp. 93-100
Author(s):  
Lalita El Milla

Scaffolds is three dimensional structure that serves as a framework for bone growth. Natural materials are often used in synthesis of bone tissue engineering scaffolds with respect to compliance with the content of the human body. Among the materials used to make scafffold was hydroxyapatite, alginate and chitosan. Hydroxyapatite powder obtained by mixing phosphoric acid and calcium hydroxide, alginate powders extracted from brown algae and chitosan powder acetylated from crab. The purpose of this study was to examine the functional groups of hydroxyapatite, alginate and chitosan. The method used in this study was laboratory experimental using Fourier Transform Infrared (FTIR) spectroscopy for hydroxyapatite, alginate and chitosan powders. The results indicated the presence of functional groups PO43-, O-H and CO32- in hydroxyapatite. In alginate there were O-H, C=O, COOH and C-O-C functional groups, whereas in chitosan there were O-H, N-H, C=O, C-N, and C-O-C. It was concluded that the third material containing functional groups as found in humans that correspond to the scaffolds material in bone tissue engineering.


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