Photoacoustic determination of glucose concentration in whole blood by a near-infrared laser diode

Author(s):  
Zuomin Zhao ◽  
Risto A. Myllylae
2005 ◽  
Vol 77 (14) ◽  
pp. 4587-4594 ◽  
Author(s):  
Airat K. Amerov ◽  
Jun Chen ◽  
Gary W. Small ◽  
Mark A. Arnold

1992 ◽  
Vol 46 (10) ◽  
pp. 1575-1578 ◽  
Author(s):  
David M. Haaland ◽  
M. Ries Robinson ◽  
Gary W. Koepp ◽  
Edward V. Thomas ◽  
R. Philip Eaton

Noninvasive monitoring of glucose in diabetic patients is feasible with the use of near-infrared spectroscopic measurements. As a step toward the final goal of the development of a noninvasive monitor, the near-infrared spectra (4250 to 6600 cm−1) of glucose-doped whole blood samples were obtained along with reference glucose values. Glucose concentrations and spectra of blood samples obtained from four subjects were subjected to multivariate calibration with the use of partial least-squares (PLS) methods. The cross-validated PLS standard errors of prediction for glucose concentration based on data obtained from each individual subject's blood samples averaged 33 mg/dL over the range from 3 to 743 mg/dL. Cross-validated standard errors for glucose concentration from PLS calibrations based on data from all four subjects were 39 mg/dL. However, when PLS models based upon three subjects' data were used for prediction on the fourth, glucose prediction abilities were poor. It is suggested that blood chemistry differences were sufficiently different for the four subjects to require that a larger number of subjects be included in the calibration for adequate prediction abilities to be obtained from near-infrared spectra of blood from subjects not included in the calibration.


1990 ◽  
Vol 23 (4) ◽  
pp. 719-734 ◽  
Author(s):  
M. Alexandra Roberson ◽  
Daniel Andrews-wilberforce ◽  
Diane C. Norris ◽  
Gabor Patonay

2020 ◽  
Vol 20 (1) ◽  
pp. 351-358
Author(s):  
Jihoon Kim ◽  
Sungwook Choi ◽  
Seul-Lee Lee ◽  
Min Seok Kim ◽  
Do Kyung Kim ◽  
...  

1989 ◽  
Vol 61 (13) ◽  
pp. 1425-1427 ◽  
Author(s):  
Ed. Unger ◽  
Gabor. Patonay

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