Infrared laser delivery system using hollow fibers

2001 ◽  
Author(s):  
Yuji Matsuura ◽  
Yukio Abe ◽  
Shintaro Mohri ◽  
Yi-Wei Shi ◽  
Mitsunobu Miyagi
2001 ◽  
Vol 33 (5) ◽  
pp. 279-283 ◽  
Author(s):  
Yuji Matsuura ◽  
Yi-Wei Shi ◽  
Yukio Abe ◽  
Masaru Yaegashi ◽  
Goro Takada ◽  
...  

2019 ◽  
Vol 7 (24) ◽  
pp. 3811-3825 ◽  
Author(s):  
Panchanathan Manivasagan ◽  
Seung Won Jun ◽  
Van Tu Nguyen ◽  
Nguyen Thanh Phong Truong ◽  
Giang Hoang ◽  
...  

FA–COS–TGA–GNRs–DOX have been successfully designed as a drug delivery system for chemo-photothermal combination therapy.


2011 ◽  
Vol 47 (42) ◽  
pp. 11674 ◽  
Author(s):  
Liang Wu ◽  
Yuandong Dou ◽  
Kaili Lin ◽  
Wanyin Zhai ◽  
Wenguo Cui ◽  
...  

2017 ◽  
Vol 88 (21) ◽  
pp. 2425-2434 ◽  
Author(s):  
Tin Wai Cheung ◽  
Xue Luo ◽  
Li Li

Fiber technology has stepped into an essential position in the textile industry. It is forecasted that smart textiles will keep on developing constantly and vigorously. Having a convenient drug delivery system for treating various illnesses and bacterial infections is always in demand. Hollow fibers, which consist of a hollow structure and exceptional characteristics, such as high loading capacity and high surface reactivity, have been considerably used in medical equipment. A pilot study was performed in this paper for opening up environmentally friendly, convenient and repeatable drug delivery functions of industrial, ready-made hollow fibers for sustainable development in various aspects. The hollow fiber drug delivery system of this project is believed to tackle the challenges observed from the traditional drug delivery system, which include the following: (1) replacement of one-time delivery by repeatable drug loading and releasing; (2) loading complex drugs, such as in Chinese medicine; (3) using common materials available in the current textile market. Nylon 6 hollow fiber was the main subject of the pilot study. Its drug loading capability was investigated with the application of woven fabrics via the process of simple and direct drug loading under negative pressure (i.e. vacuum). The antibacterial performance of the drug-loaded fabrics and the drug release kinetics of the hollow fibers were examined.


2003 ◽  
Vol 8 (2) ◽  
pp. 342-350 ◽  
Author(s):  
Evelyne Zeira ◽  
Alexandra Manevitch ◽  
Artium Khatchatouriants ◽  
Orit Pappo ◽  
Esti Hyam ◽  
...  

2014 ◽  
Vol 29 (5) ◽  
pp. 769-779 ◽  
Author(s):  
Xiali Zhu ◽  
Yingxia Xie ◽  
Yingjie Zhang ◽  
Heqing Huang ◽  
Shengnan Huang ◽  
...  

This report focuses on the thermo-sensitive liposomes loaded with doxorubicin and lysine-modified single-walled carbon nanotube drug delivery system, which was designed to enhance the anti-tumor effect and reduce the side effects of doxorubicin. Doxorubicin-lysine/single-walled carbon nanotube-thermo-sensitive liposomes was prepared by reverse-phase evaporation method, the mean particle size was 232.0 ± 5.6 nm, and drug entrapment efficiency was 86.5 ± 3.7%. The drug release test showed that doxorubicin released more quickly at 42℃ than at 37℃. Compared with free doxorubicin, doxorubicin-lysine/single-walled carbon nanotube-thermo-sensitive liposomes could efficiently cross the cell membranes and afford higher anti-tumor efficacy on the human hepatic carcinoma cell line (SMMC-7721) cells in vitro. For in vivo experiments, the relative tumor volumes of the sarcomaia 180-bearing mice in thermo-sensitive liposomes group and doxorubicin group were significantly smaller than those of N.S. group. Meanwhile, the combination of near-infrared laser irradiation at 808 nm significantly enhanced the tumor growth inhibition both on SMMC-7721 cells and the sarcomaia 180-bearing mice. The quality of life such as body weight, mental state, food and water intake of sarcomaia 180 tumor-bearing mice treated with doxorubicin-lysine/single-walled carbon nanotube-thermo-sensitive liposomes were much higher than those treated with doxorubicin. In conclusion, doxorubicin-lysine/single-walled carbon nanotube-thermo-sensitive liposomes combined with near-infrared laser irradiation at 808 nm may potentially provide viable clinical strategies for targeting delivery of anti-cancer drugs.


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