Spatially resolved diffuse reflectance with laser Doppler imaging for the simultaneous in-vivo measurement of tissue perfusion and metabolic state

2000 ◽  
Author(s):  
Kevin R. Forrester ◽  
Roxane Shymkiw ◽  
John Tulip ◽  
Craig Sutherland ◽  
David Hart ◽  
...  
Keyword(s):  
Diffuse Reflectance ◽  
Tissue Perfusion ◽  
Laser Doppler ◽  
Doppler Imaging ◽  
Laser Doppler Imaging ◽  
Metabolic State ◽  
In Vivo Measurement ◽  
Spatially Resolved

LAZERINĖS DOPLEROGRAFIJOS VERTĖ NUDEGIMŲ DIAGNOSTIKOJE IR GYDYME

2013 ◽  
Vol 23 (2) ◽  
pp. 98-103
Author(s):  
Algirda Venclauskienė ◽  
Algidas Basevičius ◽  
Ernestas Zacharevskij ◽  
Vytautas Vaičekauskas ◽  
Saulius Lukoševičius ◽  
...  
Keyword(s):  
Tissue Perfusion ◽  
Laser Doppler ◽  
Doppler Imaging ◽  
Prospective Clinical Study ◽  
Burn Patients ◽  
Laser Doppler Imaging ◽  
Burn Wound ◽  
Cost Of Treatment ◽  
The Cost ◽  
Burn Depth

The main treatment of deep burns is early excision of injuried tissues which reduce inpatient stay and decrease the cost of treatment. The clinical burn depth examination is still widely used in clinical practice which isn‘t accuracy and belongs of physician experience. The laser doppler imaging is mostly use method of burn depth examination. The aim of study – to estimate the accuracy of different methods of 2A and 2B degree of burn depth examination and to assess the importance of these methods of burn wound spontaneous epithelization. Methods. Prospective clinical study of 44 burned patients. The burned patients were examined 72 hours, 7 and 14 days after injury. The clinical burn depth examination, laser doppler imaging and tissue biopsy were made for all burned patients. The accuracy, sensitivity and specificity of different methods were analyzed. The burned tissue perfusion velocity and spontaneous burn wound epithelization were analyzed using laser doppler imaging examination. Results. The flame was the main reason of burn. Most of burn patients were male. The perfusion velocity was higher of conservatively treated patients compared with surgery patients. The critical perfusion velocity was since 55 to 149 PU. The perfusion velocity higher than 149 PU concluded higher rate of spontaneous burn wound epithelization. Conclusions. The laser doppler imaging enables to prognosticate spontaneous epithelization of burn wound and welltime select for surgical treatment of burned injuries.http://dx.doi.org/10.5200/sm-hs.2013.053 Article in Lithuanian

scholarly journals High-speed wave-mixing laser Doppler imaging in vivo

2008 ◽  
Vol 33 (8) ◽  
pp. 842 ◽  
Author(s):  
M. Atlan ◽  
M. Gross ◽  
T. Vitalis ◽  
A. Rancillac ◽  
J. Rossier ◽  
...  
Keyword(s):  
High Speed ◽  
Laser Doppler ◽  
Doppler Imaging ◽  
Wave Mixing ◽  
Laser Doppler Imaging

Evaluation of an infrared laser-Doppler blood flowmeter

1987 ◽  
Vol 252 (6) ◽  
pp. G832-G839 ◽  
Author(s):  
A. P. Shepherd ◽  
G. L. Riedel ◽  
J. W. Kiel ◽  
D. J. Haumschild ◽  
L. C. Maxwell
Keyword(s):  
Rotational Velocity ◽  
Rotating Disk ◽  
Tissue Perfusion ◽  
Infrared Laser ◽  
Blood Oxygenation ◽  
Laser Doppler ◽  
Laser Doppler Velocimeter ◽  
Flow Signal

Several laser-Doppler blood flowmeters are now commercially available; however, only one utilizes an infrared laser diode (Laserflo, TSI, St. Paul, MN). Because of this and other unique features such as its microprocessor-based signal analyzer, we evaluated this device's ability to measure tissue perfusion. Initially, we determined whether laser illumination directly affected the microvasculature. Intravital microscopic observations in the hamster cremaster muscle indicated that neither He-Ne nor infrared laser light affected the diameters of arterioles that were responsive to vasoactive agents. To test the flowmeter for linearity and repeatability, we used a rotating disk to simulate a light-scattering, flowing medium. The "flow" signal was highly correlated (r = 0.99) with the rotational velocity of the disk, was consistent among flow probes, and showed a high degree of reproducibility. The second model consisted of microsphere suspensions pumped through cuvettes. The laser-Doppler velocimeter (LDV) flow signal was linear with respect to pump output. With red blood cells in the perfusate, we examined the effects of blood oxygenation on the flowmeter's performance. The LDV flow signal was unaffected by changes in blood oxygenation. We evaluated linearity in vivo in isolated, perfused rat livers and in isolated canine gastric flaps. We observed linear relationships between total flow and laser-Doppler flow measured on the surface of the liver (r = 0.98) and in the gastric mucosa (r = 0.98), but the slopes of the relationships between total and local LDV flow showed considerable variability not noted in the in vitro studies.(ABSTRACT TRUNCATED AT 250 WORDS)

Sign in / Sign up

Export Citation Format

Share Document