Supervision of pharmaceutical glass container manufacturing process.

2000 ◽  
Author(s):  
Francisco J. Meca Meca ◽  
Francisco J. Rodriguez Sanchez ◽  
Jose A. Jimenez Calvo ◽  
Diego Lillo Rodriguez
2011 ◽  
Vol 133 (2) ◽  
Author(s):  
C. G. Giannopapa ◽  
J. A. W. M. Groot

The blow-blow forming process is a widely used technique in glass container manufacturing (e.g., production of glass bottles and jars). This process typically takes few seconds and is characterized by large deformations and temperature gradients. In the work of Giannopapa (2008, “Development of a Computer Simulation Model for Blowing Glass Containers,” ASME J. Manuf. Sci. Eng., 130, p. 041003), the development of a computer simulation model for glass blowing was presented and demonstrated on dummy problems with an initially uniform glass temperature. The objective of this paper is to extend and further develop the simulation model to be used for industrial purposes. To achieve this, both steps of the blow-blow forming process of glass containers are simulated and tested against real industrial problems. In this paper, a nonuniform temperature distribution is considered for the blowing of the preform, which is reconstructed from temperature data provided by the industry. The model is validated by means of several examples regarding conservation properties, behavior of the flow, and comparison of the glass thickness with experimental measurements. Furthermore, by means of these examples, the sensitivity of the glass thickness to inaccuracies in the measurement and reconstruction of the initial temperature distribution is verified.


2003 ◽  
Vol 125 (3) ◽  
pp. 476-483 ◽  
Author(s):  
M. K. Ramasubramanian ◽  
K. Muthuraman

The manufacturing process of brim forming in paperboard containers consists of taking a thin paperboard shell and forming a brim to provide additional stiffness to the structure. A paper cup is an example of such a structure manufactured at rates exceeding 300 units per minute. A realistic model for the manufacturing process is not available and the effects of process and material parameters are not well understood. In this study, a finite element model of this highly nonlinear problem is presented. The model takes into account the material orthotropy and nonlinear elastic-plastic behavior, die paperboard contact interaction during loading and unloading, and friction between the metal die and paperboard, die geometry, and environmental conditions. Model predictions of the force-displacement curve agree well with the experimentally observed results.


Author(s):  
M. Shlepr ◽  
C. M. Vicroy

The microelectronics industry is heavily tasked with minimizing contaminates at all steps of the manufacturing process. Particles are generated by physical and/or chemical fragmentation from a mothersource. The tools and macrovolumes of chemicals used for processing, the environment surrounding the process, and the circuits themselves are all potential particle sources. A first step in eliminating these contaminants is to identify their source. Elemental analysis of the particles often proves useful toward this goal, and energy dispersive spectroscopy (EDS) is a commonly used technique. However, the large variety of source materials and process induced changes in the particles often make it difficult to discern if the particles are from a common source.Ordination is commonly used in ecology to understand community relationships. This technique usespair-wise measures of similarity. Separation of the data set is based on discrimination functions. Theend product is a spatial representation of the data with the distance between points equaling the degree of dissimilarity.


1952 ◽  
Vol 44 (3) ◽  
pp. 449-449
Author(s):  
Rudolph Allgeier ◽  
Reuben Wisthoff ◽  
Frank Hildebrandt

1993 ◽  
Vol 13 (S 01) ◽  
pp. S5-S11 ◽  
Author(s):  
Debra Hoppensteadt ◽  
Jeanine Walenga ◽  
A Ahsan ◽  
O Iqbal ◽  
W Jeske ◽  
...  

SummaryThe introduction of low molecular weight heparins has added a new dimension to the pharmacological management of thrombotic disorders. Because of different chemical and pharmacological characteristics, due to the manufacturing process, each LMWH should be considered as a distinct entitity and only be used for its given indication. A list of commercially available LMWHs is included. The mechanism of action of the LMWHs and their use in various disorders are discussed. Available laboratory tests for monitoring LMWHs are presented and their limitations pointed out.


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