scholarly journals Monte-Carlo simulations of arterial imaging with optical coherence tomography

2000 ◽  
Author(s):  
Peter A. Amendt ◽  
Kent G. Estabrook ◽  
Matthew J. Everett ◽  
Richard A. London ◽  
Duncan J. Maitland ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Monte Carlo ◽  
Monte Carlo Simulations ◽  
Optical Coherence ◽  
Arterial Imaging

Modeling the optical coherence tomography geometry using the extended Huygens-Fresnel principle and Monte Carlo simulations

2000 ◽  
Author(s):  
Peter E. Andersen ◽  
Lars Thrane ◽  
Harold T. Yura ◽  
Andreas Tycho ◽  
Thomas M. Joergensen
Keyword(s):  
Optical Coherence Tomography ◽  
Monte Carlo ◽  
Monte Carlo Simulations ◽  
Optical Coherence

Modeling the optical coherence tomography geometry using the extended Huygens-Fresnel principle and Monte Carlo simulations

2003 ◽  
Author(s):  
Peter E. Andersen ◽  
Lars Thrane ◽  
Harold T. Yura ◽  
Andreas Tycho ◽  
Thomas M. Jorgensen
Keyword(s):  
Optical Coherence Tomography ◽  
Monte Carlo ◽  
Monte Carlo Simulations ◽  
Optical Coherence

scholarly journals A Mesh-Based Monte Carlo Study for Investigating Structural and Functional Imaging of Brain Tissue Using Optical Coherence Tomography

2019 ◽  
Vol 9 (19) ◽  
pp. 4008
Author(s):  
Luying Yi ◽  
Liqun Sun ◽  
Mingli Zou ◽  
Bo Hou
Keyword(s):  
Optical Coherence Tomography ◽  
Monte Carlo ◽  
Brain Imaging ◽  
Brain Tissue ◽  
Three Dimensional ◽  
Hemoglobin Concentration ◽  
Monte Carlo Study ◽  
Biological Tissues ◽  
Optical Coherence ◽  
Quantitative Accuracy

Optical coherence tomography (OCT) can obtain high-resolution three-dimensional (3D) structural images of biological tissues, and spectroscopic OCT, which is one of the functional extensions of OCT, can also quantify chromophores of tissues. Due to its unique features, OCT has been increasingly used for brain imaging. To support the development of the simulation and analysis tools on which OCT-based brain imaging depends, a model of mesh-based Monte Carlo for OCT (MMC-OCT) is presented in this work to study OCT signals reflecting the structural and functional activities of brain tissue. In addition, an approach to improve the quantitative accuracy of chromophores in tissue is proposed and validated by MMC-OCT simulations. Specifically, the OCT-based brain structural imaging was first simulated to illustrate and validate the MMC-OCT strategy. We then focused on the influences of different wavelengths on the measurement of hemoglobin concentration C, oxygen saturation Y, and scattering coefficient S in brain tissue. Finally, it is proposed and verified here that the measurement accuracy of C, Y, and S can be improved by selecting appropriate wavelengths for calculation, which contributes to the experimental study of brain functional sensing.

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