Evaluation of laser Doppler flowmetry system with fast signal processing using an autoregressive process model

1999 ◽  
Author(s):  
Peter Elter ◽  
Wilhelm Stork ◽  
Klaus-Dieter Mueller-Glaser ◽  
Norbert O. Lutter
Keyword(s):  
Signal Processing ◽  
Laser Doppler Flowmetry ◽  
Process Model ◽  
Autoregressive Process ◽  
Laser Doppler ◽  
Doppler Flowmetry

Higher-order spectral analysis in laser-Doppler flowmetry signal processing

1999 ◽  
Vol 7 (2-3) ◽  
pp. 85-101 ◽  
Author(s):  
Vassilios Alexopoulos ◽  
Stefanos Kollias ◽  
Philippe Leger ◽  
Henry Boccalon ◽  
Zoltan Csiki
Keyword(s):  
Signal Processing ◽  
Spectral Analysis ◽  
Laser Doppler Flowmetry ◽  
Higher Order ◽  
Laser Doppler ◽  
Doppler Flowmetry

The response of skin perfusion and of rheological and immunological variables to intravenous prostanoid administration in Raynaud’s phenomenon secondary to collagenosis

VASA ◽  
2005 ◽  
Vol 34 (4) ◽  
pp. 243-249 ◽  
Author(s):  
Drinda ◽  
Neumann ◽  
Pöhlmann ◽  
Vogelsang ◽  
Stein ◽  
...  
Keyword(s):  
Laser Doppler Flowmetry ◽  
Raynaud’S Phenomenon ◽  
Raynaud's Phenomenon ◽  
Plasma Viscosity ◽  
Laser Doppler ◽  
Erythrocyte Aggregation ◽  
Control Group ◽  
Long Term Effects ◽  
Doppler Flowmetry

Background: Prostanoids are used in the treatment of Raynaud’s phenomenon and acral perfusion disorders secondary to collagenosis. In subjective terms, intravenous administration of these agents produces success in more than 50% of patients. The therapeutic outcome of clinical administration of alprostadil or iloprost may vary from individual to individual. Patients and methods: The following variables were analysed in a cross-over study in 27 patients with collagenosis and Raynaud’s phenomenon: plasma viscosity and erythrocyte aggregation (rheological variables), partial pressure of oxygen and laser Doppler flowmetry in the finger region, and lymphocyte phenotyping and interleukin (IL) determinations (immunological variables). Results: Laser Doppler flowmetry revealed significant differences between patients with secondary Raynaud’s phenomenon and a control group of 25 healthy subjects. Laser Doppler readings did not change significantly as a result of the treatments. Therapy with iloprost produced a reduction in IL-1beta, L-selectin (CD 62 L) and IL-6. Conclusion: The change in immunological variables due to iloprost may explain the long-term effects of prostaglandins in the treatment of Raynaud’s phenomenon. From our results it is not possible to infer any preference for iloprost or alprostadil.

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