Alaysis of image features of histograms of edge gradient for false positive reduction in lung nodule detection in chest radiographs

Author(s):  
Xin-Wei Xu ◽  
Shigehiko Katsuragawa ◽  
Kazuto Ashizawa ◽  
Heber MacMahon ◽  
Kunio Doi
2021 ◽  
Author(s):  
Negar Memarian

This thesis is based on the original investigations of the author in the field of computerized lung nodule detection in computed tomography (CT) images. The methodologies discussed in this thesis include two main topics: region of interest detection and enhanced false positive (FP) reduction. The system, which is developed to be a supplementary diagnostic tool for radiologists, first spots all the regions suspected to be nodules in the lung. Then it pins down the candidates with the highest possibility of being nodules through a series of rule based filtering stages. Finally, an enhanced false positive reduction system, which is in fact designed as a hybrid scheme based on learning algorithms, reduces the false positive detections further. The overall system performs with 72% sensitivity and 2.42 FP/slice, which competes with state-of-the-art methods. The system was tested on a database consisting of 24 pediatric clinical subjects with 1190 images and 154 metastatic nodules.


2021 ◽  
Author(s):  
Negar Memarian

This thesis is based on the original investigations of the author in the field of computerized lung nodule detection in computed tomography (CT) images. The methodologies discussed in this thesis include two main topics: region of interest detection and enhanced false positive (FP) reduction. The system, which is developed to be a supplementary diagnostic tool for radiologists, first spots all the regions suspected to be nodules in the lung. Then it pins down the candidates with the highest possibility of being nodules through a series of rule based filtering stages. Finally, an enhanced false positive reduction system, which is in fact designed as a hybrid scheme based on learning algorithms, reduces the false positive detections further. The overall system performs with 72% sensitivity and 2.42 FP/slice, which competes with state-of-the-art methods. The system was tested on a database consisting of 24 pediatric clinical subjects with 1190 images and 154 metastatic nodules.


IEEE Access ◽  
2019 ◽  
Vol 7 ◽  
pp. 67380-67391 ◽  
Author(s):  
Haichao Cao ◽  
Hong Liu ◽  
Enmin Song ◽  
Guangzhi Ma ◽  
Xiangyang Xu ◽  
...  

Author(s):  
Xiaoqi Lu ◽  
Yu Gu ◽  
Lidong Yang ◽  
Baohua Zhang ◽  
Ying Zhao ◽  
...  

Objective: False-positive nodule reduction is a crucial part of a computer-aided detection (CADe) system, which assists radiologists in accurate lung nodule detection. In this research, a novel scheme using multi-level 3D DenseNet framework is proposed to implement false-positive nodule reduction task. Methods: Multi-level 3D DenseNet models were extended to differentiate lung nodules from falsepositive nodules. First, different models were fed with 3D cubes with different sizes for encoding multi-level contextual information to meet the challenges of the large variations of lung nodules. In addition, image rotation and flipping were utilized to upsample positive samples which consisted of a positive sample set. Furthermore, the 3D DenseNets were designed to keep low-level information of nodules, as densely connected structures in DenseNet can reuse features of lung nodules and then boost feature propagation. Finally, the optimal weighted linear combination of all model scores obtained the best classification result in this research. Results: The proposed method was evaluated with LUNA16 dataset which contained 888 thin-slice CT scans. The performance was validated via 10-fold cross-validation. Both the Free-response Receiver Operating Characteristic (FROC) curve and the Competition Performance Metric (CPM) score show that the proposed scheme can achieve a satisfactory detection performance in the falsepositive reduction track of the LUNA16 challenge. Conclusion: The result shows that the proposed scheme can be significant for false-positive nodule reduction task.


Sign in / Sign up

Export Citation Format

Share Document