Experimental investigation of laser ablation efficiency of metals

Author(s):  
Catherine Chaleard ◽  
Vincent Detalle ◽  
Sylvain Kocon ◽  
Jean-Luc Lacour ◽  
Corinne Nouvellon ◽  
...  
2002 ◽  
Vol 20 (1) ◽  
pp. 67-72 ◽  
Author(s):  
A. SEMEROK ◽  
B. SALLÉ ◽  
J.-F. WAGNER ◽  
G. PETITE

Crater shapes and plasma plume expansion in the interaction of sharply focused laser beams (10 μm waist diameter, 60 fs–6 ns pulse duration) with metals in air at atmospheric pressure were studied. Laser ablation efficiencies and rates of plasma expansion were determined. The best ablation efficiency was observed with femtosecond laser pulses. It was found that for nanosecond pulses, the laser beam absorption, its scattering, and its reflection in plasma were the limiting factors for efficient laser ablation and precise material sampling with sharply focused laser beams. The experimental results obtained were analyzed with relation to different theoretical models of laser ablation.


2016 ◽  
Vol 13 (10) ◽  
pp. 106002 ◽  
Author(s):  
M A Valverde-Alva ◽  
T García-Fernández ◽  
E Esparza-Alegría ◽  
M Villagrán-Muniz ◽  
C Sánchez-Aké ◽  
...  

SPIE Newsroom ◽  
2015 ◽  
Author(s):  
Juergen Sotrop ◽  
Jan Winter ◽  
Stephan Rapp ◽  
Heinz P. Huber

Laser Physics ◽  
2008 ◽  
Vol 18 (4) ◽  
pp. 374-379 ◽  
Author(s):  
J. Hermann ◽  
S. Noël ◽  
T. E. Itina ◽  
E. Axente ◽  
M. E. Povarnitsyn

2016 ◽  
Vol 41 (4) ◽  
pp. E11 ◽  
Author(s):  
Mir Amaan Ali ◽  
Kate T. Carroll ◽  
Robert C. Rennert ◽  
Thomas Hamelin ◽  
Leon Chang ◽  
...  

OBJECTIVE Therapeutic options for brain metastases (BMs) that recur after stereotactic radiosurgery (SRS) remain limited. METHODS The authors provide the collective experience of 4 institutions where treatment of BMs that recurred after SRS was performed with stereotactic laser ablation (SLA). RESULTS Twenty-six BMs (in 23 patients) that recurred after SRS were treated with SLA (2 patients each underwent 2 SLAs for separate lesions, and a third underwent 2 serial SLAs for discrete BMs). Histological findings in the BMs treated included the following: breast (n = 6); lung (n = 6); melanoma (n = 5); colon (n = 2); ovarian (n = 1); bladder (n = 1); esophageal (n = 1); and sarcoma (n = 1). With a median follow-up duration of 141 days (range 64–794 days), 9 of the SLA-treated BMs progressed despite treatment (35%). All cases of progression occurred in BMs in which < 80% ablation was achieved, whereas no disease progression was observed in BMs in which ≥ 80% ablation was achieved. Five BMs were treated with SLA, followed 1 month later by adjuvant SRS (5 Gy daily × 5 days). No disease progression was observed in these patients despite ablation efficiency of < 80%, suggesting that adjuvant hypofractionated SRS enhances the efficacy of SLA. Of the 23 SLA-treated patients, 3 suffered transient hemiparesis (13%), 1 developed hydrocephalus requiring temporary ventricular drainage (4%), and 1 patient who underwent SLA of a 28.9-cm3 lesion suffered a neurological deficit requiring an emergency hemicraniectomy (4%). Although there is significant heterogeneity in corticosteroid treatment post-SLA, most patients underwent a 2-week taper. CONCLUSIONS Stereotactic laser ablation is an effective treatment option for BMs in which SRS fails. Ablation of ≥ 80% of BMs is associated with decreased risk of disease progression. The efficacy of SLA in this setting may be augmented by adjuvant hypofractionated SRS.


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