scholarly journals CsI(Na)-based radiation detector for high-resolution imaging studies using iodine 125 in small-animal research

1997 ◽  
Author(s):  
Andrew G. Weisenberger ◽  
Eric Bradley ◽  
Stan Majewski ◽  
Margaret Saha
Keyword(s):  
High Resolution ◽  
Radiation Detector ◽  
Small Animal ◽  
Animal Research ◽  
High Resolution Imaging ◽  
Imaging Studies ◽  
Resolution Imaging ◽  
Iodine 125 ◽  
Small Animal Research

scholarly journals Ultrasound Biomicroscopy in Small Animal Research: Applications in Molecular and Preclinical Imaging

2012 ◽  
Vol 2012 ◽  
pp. 1-14 ◽  
Author(s):  
A. Greco ◽  
M. Mancini ◽  
S. Gargiulo ◽  
M. Gramanzini ◽  
P. P. Claudio ◽  
...  
Keyword(s):  
High Resolution ◽  
Power Doppler ◽  
Small Animal ◽  
Ultrasound Biomicroscopy ◽  
Animal Research ◽  
High Resolution Imaging ◽  
Cardiovascular Development ◽  
Preclinical Imaging ◽  
Resolution Imaging ◽  
Small Animal Research

Ultrasound biomicroscopy (UBM) is a noninvasive multimodality technique that allows high-resolution imaging in mice. It is affordable, widely available, and portable. When it is coupled to Doppler ultrasound with color and power Doppler, it can be used to quantify blood flow and to image microcirculation as well as the response of tumor blood supply to cancer therapy. Target contrast ultrasound combines ultrasound with novel molecular targeted contrast agent to assess biological processes at molecular level. UBM is useful to investigate the growth and differentiation of tumors as well as to detect early molecular expression of cancer-related biomarkersin vivoand to monitor the effects of cancer therapies. It can be also used to visualize the embryological development of mice in uterus or to examine their cardiovascular development. The availability of real-time imaging of mice anatomy allows performing aspiration procedures under ultrasound guidance as well as the microinjection of cells, viruses, or other agents into precise locations. This paper will describe some basic principles of high-resolution imaging equipment, and the most important applications in molecular and preclinical imaging in small animal research.

A versatile turbulence simulator for high-resolution imaging studies of astronomical targets

2020 ◽  
Author(s):  
Caleb Abbott ◽  
Arturo O. Martinez ◽  
Stuart M. Jefferies ◽  
Theo ten Brummelaar ◽  
Fabien Baron
Keyword(s):  
High Resolution ◽  
High Resolution Imaging ◽  
Imaging Studies ◽  
Resolution Imaging

scholarly journals Preparation of Human Inner Ear Structures for High Resolution Imaging Studies

2017 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Marjan Mirsalehi ◽  
Saleh Mohebbi ◽  
Sedigheh Ebrahimpoor ◽  
Mark Philip Kuhnel ◽  
Thomas Lenarz ◽  
...  
Keyword(s):  
High Resolution ◽  
Inner Ear ◽  
High Resolution Imaging ◽  
Imaging Studies ◽  
Resolution Imaging ◽  
Human Inner Ear

High Resolution SPECT in Small Animal Research

2001 ◽  
Vol 12 (2) ◽  
Author(s):  
Andreas Wirrwar ◽  
Nils Schramm ◽  
Henning Vosberg ◽  
Hans-Wilhelm Müller-Gärtner
Keyword(s):  
High Resolution ◽  
Small Animal ◽  
Animal Research ◽  
Small Animal Research

Alternative approaches to ultra-high resolution imaging

1991 ◽  
Vol 49 ◽  
pp. 650-651
Author(s):  
J.M. Cowley
Keyword(s):  
High Resolution ◽  
High Voltage ◽  
High Resolution Electron Microscopy ◽  
Crystal Defects ◽  
High Resolution Imaging ◽  
General Applicability ◽  
Resolution Electron ◽  
Radiation Resistant ◽  
Resolution Imaging ◽  
Alternative Approaches

By extrapolation of past experience, it would seem that the future of ultra-high resolution electron microscopy rests with the advances of electron optical engineering that are improving the instrumental stability of high voltage microscopes to achieve the theoretical resolutions of 1Å or better at 1MeV or higher energies. While these high voltage instruments will undoubtedly produce valuable results on chosen specimens, their general applicability has been questioned on the basis of the excessive radiation damage effects which may significantly modify the detailed structures of crystal defects within even the most radiation resistant materials in a period of a few seconds. Other considerations such as those of cost and convenience of use add to the inducement to consider seriously the possibilities for alternative approaches to the achievement of comparable resolutions.

Principle and practice of high-resolution imaging with a field-emission TEM

1992 ◽  
Vol 50 (1) ◽  
pp. 138-139
Author(s):  
Max T. Otten ◽  
Wim M.J. Coene
Keyword(s):  
High Resolution ◽  
Field Emission ◽  
Incidence Angle ◽  
Temporal Coherence ◽  
Energy Spread ◽  
High Resolution Imaging ◽  
Major Improvement ◽  
High Resolution Images ◽  
Resolution Imaging

High-resolution imaging with a LaB6 instrument is limited by the spatial and temporal coherence, with little contrast remaining beyond the point resolution. A Field Emission Gun (FEG) reduces the incidence angle by a factor 5 to 10 and the energy spread by 2 to 3. Since the incidence angle is the dominant limitation for LaB6 the FEG provides a major improvement in contrast transfer, reducing the information limit to roughly one half of the point resolution. The strong improvement, predicted from high-resolution theory, can be seen readily in diffractograms (Fig. 1) and high-resolution images (Fig. 2). Even if the information in the image is limited deliberately to the point resolution by using an objective aperture, the improved contrast transfer close to the point resolution (Fig. 1) is already worthwhile.

Imaging of ferroelectric domain walls by electron holography

1992 ◽  
Vol 50 (1) ◽  
pp. 246-247
Author(s):  
Xiao Zhang
Keyword(s):  
Magnetic Field ◽  
High Resolution ◽  
Domain Walls ◽  
Ferroelectric Domain ◽  
Object Wave ◽  
Electron Holography ◽  
High Resolution Imaging ◽  
Quantitative Measurements ◽  
Resolution Imaging ◽  
Electron Microscopes

Electron holography has recently been available to modern electron microscopy labs with the development of field emission electron microscopes. The unique advantage of recording both amplitude and phase of the object wave makes electron holography a effective tool to study electron optical phase objects. The visibility of the phase shifts of the object wave makes it possible to directly image the distributions of an electric or a magnetic field at high resolution. This work presents preliminary results of first high resolution imaging of ferroelectric domain walls by electron holography in BaTiO3 and quantitative measurements of electrostatic field distribution across domain walls.

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