Short-pulse laser beam interactions with biocompatible polymer materials and tissue

1996 ◽  
Author(s):  
Alexander A. Serafetinides
Keyword(s):  
Laser Beam ◽  
Pulse Laser ◽  
Short Pulse ◽  
Polymer Materials ◽  
Biocompatible Polymer ◽  
Pulse Laser Beam ◽  
Short Pulse Laser

scholarly journals STUDY OF FOCUSING INTO CLOSELY SPACED SPOTS VIA ILLUMINATING A DIFFRACTIVE OPTICAL ELEMENT BY A SHORT-PULSE LASER BEAM

2015 ◽  
Vol 39 (2) ◽  
pp. 187-196 ◽  
Author(s):  
S. N. Khonina ◽  
S. A. Degtyarev ◽  
A. P. Porfirev ◽  
O. Yu. Moiseev ◽  
S. D. Poletaev ◽  
...  
Keyword(s):  
Laser Beam ◽  
Pulse Laser ◽  
Short Pulse ◽  
Optical Element ◽  
Diffractive Optical Element ◽  
Pulse Laser Beam ◽  
Short Pulse Laser

Short pulse laser beam beyond paraxial approximation

2017 ◽  
Vol 34 (8) ◽  
pp. 1351 ◽  
Author(s):  
Pierre Favier ◽  
Kevin Dupraz ◽  
Kevin Cassou ◽  
Xing Liu ◽  
Aurélien Martens ◽  
...  
Keyword(s):  
Laser Beam ◽  
Pulse Laser ◽  
Short Pulse ◽  
Paraxial Approximation ◽  
Pulse Laser Beam ◽  
Short Pulse Laser

Allowable propagation of short pulse laser beam in a plasma channel and electromagnetic solitary waves

2011 ◽  
Vol 375 (45) ◽  
pp. 4022-4028 ◽  
Author(s):  
Shan Zhang ◽  
Xue-Ren Hong ◽  
Hong-Yu Wang ◽  
Bai-Song Xie
Keyword(s):  
Laser Beam ◽  
Pulse Laser ◽  
Solitary Waves ◽  
Plasma Channel ◽  
Short Pulse ◽  
Pulse Laser Beam ◽  
Short Pulse Laser

Experimental Measurements and Numerical Modeling Validation of Temperature Distribution in Tissue Medium During Short Pulse Laser Irradiation

2007 ◽  
Author(s):  
Ashim Dutta ◽  
Kyunghan Kim ◽  
Kunal Mitra ◽  
Zhixiong Guo
Keyword(s):  
Numerical Modeling ◽  
Heat Conduction ◽  
Temperature Distribution ◽  
Laser Beam ◽  
Pulse Laser ◽  
Short Pulse ◽  
Hyperbolic Heat Conduction ◽  
Experimental Measurements ◽  
Conduction Model ◽  
Short Pulse Laser

The objective of this paper is to analyze the temperature distributions and heat affected zone in skin tissue medium when irradiated with either a collimated or a focused laser beam from a short pulse laser source. Single-layer and three-layer tissue phantoms containing embedded inhomogeneities are used as a model of human skin tissue having subsurface tumor. Q-switched Nd:YAG laser is used in this study. Experimental measurements of axial and radial temperature distribution in the tissue phantom are compared with the numerical modeling results. For numerical modeling, the transient radiative transport equation is first solved using discrete ordinates method for obtaining the intensity distribution and radiative heat flux inside the tissue medium. Then the temperature distribution is obtained by coupling the bio-heat transfer equation with either hyperbolic non-Fourier or parabolic Fourier heat conduction model. The hyperbolic heat conduction equation is solved using MacCormack’s scheme with error terms correction. It is observed that experimentally measured temperature distribution is in good agreement with that predicted by hyperbolic heat conduction model. The experimental measurements also demonstrate that converging laser beam focused directly at the subsurface location can produce desired high temperature at that location as compared to that produced by collimated laser beam for the same laser parameters.

Ablation of Subsurface Tumors Using 1552 nm Ultra-Short Pulse Laser

2008 ◽  
Author(s):  
Shreya Raje ◽  
Amir Sajjadi ◽  
Kunal Mitra ◽  
Michael S. Grace
Keyword(s):  
Laser Beam ◽  
Pulse Laser ◽  
Continuous Wave ◽  
Short Pulse ◽  
Laser Source ◽  
Short Pulse Laser ◽  
Fiber Optic Probes ◽  
Laser Immunotherapy ◽  
Ultra Short Pulse ◽  
Long Pulse

Over last two decades lasers have been used for the treatment of subsurface tumors. Various techniques such as Laser-induced Hyperthermia, Laser Interstitial Thermal Therapy (LITT), and Laser Immunotherapy have been developed for the successful ablation of subsurface tumors by different researchers. All these techniques use photo-thermal mechanism for tumor ablation by delivering thermal energy at the tumor site. In all these existing techniques, either continuous wave (CW) or long pulse laser source has been used, which often produces larger heat affected zone as compared to that produced by short pulse laser. Moreover, the delivery of laser beam at the target site is achieved through fiber optic probes which often require perforation of the skin. These drawbacks can be eliminated if a converging laser beam from a short pulse laser source is directly focused at the subsurface location to ablate the tumor.

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