A comprehensive method for simulating the effects of detector noise on speckle contrast signal

2021 ◽  
Author(s):  
Lisa Kobayashi Frisk ◽  
Manish Verma ◽  
Sumana Chetia ◽  
Chenhao P. Lin ◽  
Jason Trobaugh ◽  
...  
Keyword(s):  
Speckle Contrast ◽  
Detector Noise ◽  
Comprehensive Method

ASSESSMENT OF STATISTICAL SIGNIFICANCE OF HISTORIC DANUBE FLOODS

2020 ◽  
Author(s):  
Stevan Prohaska ◽  
◽  
Aleksandra Ilić ◽  
Pavla Pekarova ◽  
◽  
...  
Keyword(s):  
Middle Ages ◽  
Linear Trend ◽  
Statistical Significance ◽  
Danube River ◽  
Exceedance Probability ◽  
Simultaneous Occurrence ◽  
Flood Wave ◽  
Probability Of Occurrence ◽  
Comprehensive Method ◽  
Flood Hydrograph

Data on historic floods along the Danube River exist since the year 1012. In the Middle Ages, floods were estimated based on historical documents, including original handwritten notes, newspaper articles, chronicles, formal letters, books, maps and photographs. From 1500 until the beginning of organized water regime observations, floods were hydraulically reconstructed based on water marks on old buildings in cities along the Danube (Passau, Melk, Emmersdorf an der Donau, Spilz, Schonbuhen and Bratislava). The paper presents a procedure for assessing the statistical significance of registered historic floods using a comprehensive method for defining theoretical flood hydrographs at hydrological stations. The approach is based on correlation analysis of two basic flood hydrograph parameters – maximum hydrograph ordinate (peak) and flood wave volume. The PROIL model is used to define the probability of simultaneous occurrence of these parameters. It defines the exceedance probability of two random variables, in the specific case two hydrograph parameters of the form: P{Qmax more equal to qmax,p)∩(Wmax more equal to wmax,p)} = P (1) where: Qmax – maximum hydrograph ordinate (peak); qmax,p – maximum discharge of the probability of occurrence p; Wmax – maximum hydrograph volume; wmax,p – maximum flood wave volume of the probability of occurrence p; P – exceedance probability. Spatial positions of the lines of exceedance of two flood hydrograph parameters and the empirical points of the corresponding parameters of the considered historic flood in the correlation field Qmax - Wmax, allow direct assessment of the exceedance probability of a historic flood, or its statistical significance. The proposed procedure was applied in practice to assess the statistical significance of the biggest floods registered along the Danube in the sector from its mouth to the Djerdap 1 Dam. The linear trend in the time-series of maximum annual flows at a representative hydrological station and the frequency of historic floods in the considered sector of the Danube are discussed at the end of the paper.

Comprehensive method to determine flow areas of perforation damages in subsea pipelines with culverts

2019 ◽  
Vol 9 (6) ◽  
pp. 660-665
Author(s):  
Elmir I. Huseynli ◽  
◽  
Ramiz A. Eminov ◽  
Arzu E. Ibrahimova ◽  
◽  
...  
Keyword(s):  
Comprehensive Method ◽  
Subsea Pipelines

scholarly journals Retraining Convolutional Neural Networks for Specialized Cardiovascular Imaging Tasks: Lessons from Tetralogy of Fallot

2021 ◽  
Author(s):  
Animesh Tandon ◽  
Navina Mohan ◽  
Cory Jensen ◽  
Barbara E. U. Burkhardt ◽  
Vasu Gooty ◽  
...  
Keyword(s):  
Tetralogy Of Fallot ◽  
Hausdorff Distance ◽  
Volumetric Analysis ◽  
Dice Similarity Coefficient ◽  
Algorithm Performance ◽  
Comprehensive Method ◽  
Combined Use ◽  
Median Error ◽  
Structural Abnormalities ◽  
Testing Data

AbstractVentricular contouring of cardiac magnetic resonance imaging is the gold standard for volumetric analysis for repaired tetralogy of Fallot (rTOF), but can be time-consuming and subject to variability. A convolutional neural network (CNN) ventricular contouring algorithm was developed to generate contours for mostly structural normal hearts. We aimed to improve this algorithm for use in rTOF and propose a more comprehensive method of evaluating algorithm performance. We evaluated the performance of a ventricular contouring CNN, that was trained on mostly structurally normal hearts, on rTOF patients. We then created an updated CNN by adding rTOF training cases and evaluated the new algorithm’s performance generating contours for both the left and right ventricles (LV and RV) on new testing data. Algorithm performance was evaluated with spatial metrics (Dice Similarity Coefficient (DSC), Hausdorff distance, and average Hausdorff distance) and volumetric comparisons (e.g., differences in RV volumes). The original Mostly Structurally Normal (MSN) algorithm was better at contouring the LV than the RV in patients with rTOF. After retraining the algorithm, the new MSN + rTOF algorithm showed improvements for LV epicardial and RV endocardial contours on testing data to which it was naïve (N = 30; e.g., DSC 0.883 vs. 0.905 for LV epicardium at end diastole, p < 0.0001) and improvements in RV end-diastolic volumetrics (median %error 8.1 vs 11.4, p = 0.0022). Even with a small number of cases, CNN-based contouring for rTOF can be improved. This work should be extended to other forms of congenital heart disease with more extreme structural abnormalities. Aspects of this work have already been implemented in clinical practice, representing rapid clinical translation. The combined use of both spatial and volumetric comparisons yielded insights into algorithm errors.

scholarly journals Nephron blood flow dynamics measured by laser speckle contrast imaging

2011 ◽  
Vol 300 (2) ◽  
pp. F319-F329 ◽  
Author(s):  
Niels-Henrik Holstein-Rathlou ◽  
Olga V. Sosnovtseva ◽  
Alexey N. Pavlov ◽  
William A. Cupples ◽  
Charlotte Mehlin Sorensen ◽  
...  
Keyword(s):  
Blood Flow ◽  
Signal Transmission ◽  
Experimental Studies ◽  
Flow Dynamics ◽  
Laser Speckle ◽  
Tubuloglomerular Feedback ◽  
Contrast Imaging ◽  
Laser Speckle Contrast Imaging ◽  
Speckle Contrast ◽  
Blood Flow Dynamics

Tubuloglomerular feedback (TGF) has an important role in autoregulation of renal blood flow and glomerular filtration rate (GFR). Because of the characteristics of signal transmission in the feedback loop, the TGF undergoes self-sustained oscillations in single-nephron blood flow, GFR, and tubular pressure and flow. Nephrons interact by exchanging electrical signals conducted electrotonically through cells of the vascular wall, leading to synchronization of the TGF-mediated oscillations. Experimental studies of these interactions have been limited to observations on two or at most three nephrons simultaneously. The interacting nephron fields are likely to be more extensive. We have turned to laser speckle contrast imaging to measure the blood flow dynamics of 50–100 nephrons simultaneously on the renal surface of anesthetized rats. We report the application of this method and describe analytic techniques for extracting the desired data and for examining them for evidence of nephron synchronization. Synchronized TGF oscillations were detected in pairs or triplets of nephrons. The amplitude and the frequency of the oscillations changed with time, as did the patterns of synchronization. Synchronization may take place among nephrons not immediately adjacent on the surface of the kidney.

Sign in / Sign up

Export Citation Format

Share Document