A laser Doppler system for long-term recording of cerebral microcirculation in the neurointensive care unit

2021 ◽  
Author(s):  
Stina Mauritzon ◽  
Fredrik Ginstman ◽  
Karin Wardell
VASA ◽  
2005 ◽  
Vol 34 (4) ◽  
pp. 243-249 ◽  
Author(s):  
Drinda ◽  
Neumann ◽  
Pöhlmann ◽  
Vogelsang ◽  
Stein ◽  
...  

Background: Prostanoids are used in the treatment of Raynaud’s phenomenon and acral perfusion disorders secondary to collagenosis. In subjective terms, intravenous administration of these agents produces success in more than 50% of patients. The therapeutic outcome of clinical administration of alprostadil or iloprost may vary from individual to individual. Patients and methods: The following variables were analysed in a cross-over study in 27 patients with collagenosis and Raynaud’s phenomenon: plasma viscosity and erythrocyte aggregation (rheological variables), partial pressure of oxygen and laser Doppler flowmetry in the finger region, and lymphocyte phenotyping and interleukin (IL) determinations (immunological variables). Results: Laser Doppler flowmetry revealed significant differences between patients with secondary Raynaud’s phenomenon and a control group of 25 healthy subjects. Laser Doppler readings did not change significantly as a result of the treatments. Therapy with iloprost produced a reduction in IL-1beta, L-selectin (CD 62 L) and IL-6. Conclusion: The change in immunological variables due to iloprost may explain the long-term effects of prostaglandins in the treatment of Raynaud’s phenomenon. From our results it is not possible to infer any preference for iloprost or alprostadil.


Author(s):  
Hatice Ture ◽  
Sevgi Bilgen ◽  
Ozgul Keskin ◽  
Ozge Koner ◽  
Sibel Temur ◽  
...  

Author(s):  
T Yandayan ◽  
M Burdekin

The diameter of the workpiece is measured, while the workpiece is located on the CNC (computer numerical controlled) turning machine, using a new laser instrument and technique. The optical instrument is based on the laser Doppler principle, using an He—Ne laser as a light source. It obtains data by detecting the scattered light from the surface of a rotating workpiece, processing this data with respect to the rotation of the spindle and providing a value representing the workpiece diameter. The basic resolution of the system depends on the wavelength of the laser and geometry of the optics. Higher resolution can be achieved by obtaining the data from the workpiece surface over more than one complete revolution of the spindle. The resolution for one revolution of the spindle is 0.5μm and for ten 0.05μm. The measurement system is also integrated with the CNC turning machine, particularly for autofocusing of the instrument. The instrument is mounted on the tool holder of the CNC turning machine, which is focused by means of a tool offset parameter for non-contact measurement of each different diameter. Autofocusing is carried out using the MI5 machine tool interface unit which is already established for the Renishaw probe system, according to CNC part programming. The performance of the proposed technique and instrument is verified through the experiments.


1985 ◽  
Vol BME-32 (6) ◽  
pp. 439-447 ◽  
Author(s):  
Luc Duteil ◽  
Jean Claude Bernango ◽  
Wolfgang Schalla

1980 ◽  
Vol 8 (2) ◽  
pp. 426-429 ◽  
Author(s):  
Hiroshi NISHIHARA ◽  
Yasumi NISHI ◽  
Jiro KOYAMA ◽  
Noritake HOHKI ◽  
Fumihiko KAJIYA

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