Hybrid diffuse optics for bedside measurements of cerebral hemodynamics in a large cohort of stroke patients

2021 ◽  
Author(s):  
Lisa Kobayashi Frisk ◽  
Jonas B. Fischer ◽  
Izaskun Belmonte Jimeno ◽  
Anna Bosch de Basea Gomez ◽  
Marta Navarro Roman ◽  
...  
Keyword(s):  
Cerebral Hemodynamics ◽  
Large Cohort ◽  
Stroke Patients ◽  
Diffuse Optics

Migraineurs with aura present an increased cerebral hemodynamics in the anterior and posterior circulation compared with stroke patients and controls

2018 ◽  
Vol 39 (S1) ◽  
pp. 101-102 ◽  
Author(s):  
Claudia Altamura ◽  
Matteo Paolucci ◽  
Nicoletta Brunelli ◽  
Angelo Cascio Rizzo ◽  
Federica Assenza ◽  
...  
Keyword(s):  
Cerebral Hemodynamics ◽  
Posterior Circulation ◽  
Stroke Patients

scholarly journals The influence of nicergoline on cerebral, systemic and cardiac hemodynamics in patients who have had an ischemic stroke

2021 ◽  
pp. 17-26
Author(s):  
Viktor Kuznetsov
Keyword(s):  
Ischemic Stroke ◽  
Recovery Period ◽  
Peripheral Resistance ◽  
Cerebral Hemodynamics ◽  
Stroke Patients ◽  
Hemispheric Stroke ◽  
Cardiac Hemodynamics ◽  
Before And After ◽  
Blood Flow Velocities ◽  
The Right

The Aim of study was analysis of the effect of nicergoline on the cerebral, cardiac, systemic hemodynamics of patients after ischemic stroke, taking into account the hemispheric localization of the ischemic focus. Materials and methods. A comprehensive clinical and neurological examination was carried out in 38 elderly patients (mean age 64.3 ± 2.5 years) who had undergone atherothrombotic ischemic stroke in the carotid system (recovery period). There were 20 patients with left hemispheric stroke and 18 with right hemispheric stroke. All patients had arterial hypertension (AH). These were ACE inhibitors (enalapril 10-20 mg 1 tablet 2 times a day) and hydrochlorothiazide at a dose of 12.5 mg. Patients received nicergoline at a dose of 4 mg IV drip for 10 days. A comprehensive examination was carried out before and after treatment with nicergoline. The Results of the study allowed us to conclude that the course of nicergoline intake in patients after ischemic atherothrombotic stroke improves the subjective state and reduces the severity of neurological disorders, cerebral hemodynamics, increases linear systolic blood flow velocities (LBFVsys) and reduces peripheral resistance in individual extra- and intracranial vessels of the carotid and vertebro-basilar basins. In patients with right and left hemispheric localization of stroke under the influence of nicergoline, LBFVsys increases in the right and left ICA, PCA, and VA. In addition, LBFVsys increases in patients with right hemispheric stroke in the right MBA; in patients with left hemisphere - in two MBA and BA. In ischemic stroke patients, nicergoline affects systemic and cardiac hemodynamics: it reduces the systemic and cardiac hemodynamics, decreases the systemic vascular resistance and increases the ejection fraction, changes the structure of the relationship between systemic and cerebral hemodynamics, forming a positive relationship between blood pressure and hemodynamics in the vessels of the vertebro-basilar basin. Thus, the complex positive effect of nicergoline on various levels of cerebral, systemic and cardiac hemodynamics in ischemic stroke patients gives grounds to recommend the inclusion of this drug in the rehabilitation system of this category of patients.

Characterization of cerebral hemodynamics during obstructive sleep apnea by diffuse optics

2016 ◽  
Author(s):  
Clara Gregori-Pla ◽  
Peyman Zirak ◽  
Igor Blanco ◽  
Pau Bramon ◽  
Ana Fortuna ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Cerebral Hemodynamics ◽  
Diffuse Optics ◽  
Obstructive Sleep

The Pattern of Cancer in a Large Cohort of Stroke Patients

1990 ◽  
Vol 19 (3) ◽  
pp. 498-504 ◽  
Author(s):  
KNUD LINDVIG ◽  
HENRIK MØLLER ◽  
JOHANNES MOSBECH ◽  
OLE MØLLER JENSEN
Keyword(s):  
Large Cohort ◽  
Stroke Patients

Abstract 151: Enlarged Perivascular Spaces in Lacunar Stroke Patients. The Secondary Prevention of Small Subcortical Stroked (SPS3) trial.

Stroke ◽  
2012 ◽  
Vol 43 (suppl_1) ◽  
Author(s):  
Hideki Ohba ◽  
Lesly Pearce ◽  
Gillian Potter ◽  
Oscar Benavente
Keyword(s):  
Risk Factors ◽  
Cognitive Impairment ◽  
White Matter ◽  
Small Vessel Disease ◽  
Large Cohort ◽  
Common Finding ◽  
Perivascular Spaces ◽  
Lacunar Stroke ◽  
Stroke Patients ◽  
Age Related

Introduction: Enlarge perivascular spaces (EPVS) are a common finding on MRI with little known about their aetiology or clinical significance. Associations of EPVS with white matter hyperintensities (WMH) and cognitive impairment have been reported. We assessed the prevalence of EPVS in the basal ganglia (BG) and centrum semiovale (CS) and associations with vascular risk factors, MRI abnormalities, and cognitive impairment in a large cohort of MRI documented lacunar stroke patients. Methods: All SPS3 participants enrolled in North America (N=1632) were included in the cohort. MRIs were obtained at the time of index stroke. We graded severity of EPVS on T2 in each of the right and left BG and CS as: <10, 11-20, or 20+. We assessed relationships between maximum (max) BG and CS scores and patient demographics, number of subcortical infarcts, WMH, and cognitive impairment using chi-square tests and ANOVA. Logistic regression was used to identify independent associations between max score in the BG or CS (<10 vs. 11+ points) and these factors. Results: Of the 1632 MRIs, 1172 had T2-imaging available. EPVS was symmetrical in right and left sides of BG and of CS so max score in each area were used for analyses. In 42% of BG and 69% of CS, the max number of unilateral EPVS was ≥11. Patients with more EPVS in the BG were older (mean 59 vs. 63 vs. 70 years, p < 0.001), had hypertension (75% vs. 84% vs. 86% p < 0.001), and lower eGFR (mean 83 vs. 80 vs. 74 ml/min/1.73m 2 , p = 0.006). More EPVS in the BG were associated with WMH severity as measured by Age Related White Matter Changes total score (median 3 vs. 6 vs. 8, p < 0.001). Patients with more EPVS in the BG more often had multiple infarcts (11% vs. 19% vs. 29%, p<0.001). All findings were similar in the CS. Age (OR 1.9 per each 10 years, 95% CI 1.7-2.1), history of hypertension (OR 1.7, 95% CI 1.2-2.3) and multiple infarcts (OR 2.4, 95% CI 1.7-3.4) were independently associated with a maximum unilateral EPVS score of 2+ in the BG. Mild cognitive impairment was not associated with EPVS in BG (p=0.3) or CS (p=0.5). Conclusions: In this well-defined large cohort of lacunar stroke patients, BG EPVS were associated with age, hypertension and multiple infarcts. These findings suggest that BG EPVS share similar risk factors with lacunar stroke and may be a marker for small vessel disease. Unexpectedly, EPVS were not associated with cognitive impairment.

scholarly journals Transcranial Optical Monitoring of Cerebral Hemodynamics in Acute Stroke Patients during Mechanical Thrombectomy

2019 ◽  
Vol 28 (6) ◽  
pp. 1483-1494 ◽  
Author(s):  
Rodrigo M. Forti ◽  
Christopher G. Favilla ◽  
Jeffrey M. Cochran ◽  
Wesley B. Baker ◽  
John A. Detre ◽  
...  
Keyword(s):  
Acute Stroke ◽  
Mechanical Thrombectomy ◽  
Cerebral Hemodynamics ◽  
Optical Monitoring ◽  
Stroke Patients
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