Optimization of emergency material distribution path for public emergencies

2021 ◽  
Author(s):  
Zhiqiang Zhao ◽  
Guichen Wu ◽  
Sihao Chen ◽  
Ningping Hu ◽  
Heng Wang
Pharmaceutics ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 746
Author(s):  
Magdalena Turk ◽  
Rok Šibanc ◽  
Rok Dreu ◽  
Maja Frankiewicz ◽  
Małgorzata Sznitowska

This study concerned the quality of mini-tablets’ coating uniformity obtained by either the bottom spray chamber with a classical Wurster distributor (CW) or a swirl distributor (SW). Mini-tablets with a diameter of 2.0, 2.5, and 3.0 mm were coated with hypromellose using two different inlet air distributors as well as inlet airflow rates (130 and 156 m3/h). Tartrazine was used as a colorant in the coating layer and the coating uniformity was assessed by spectrophotometric analysis of solutions obtained after disintegration of the mini-tablets (n = 100). Higher uniformity of coating material distribution among the mini-tablets was observed in the case of SW distributor, even for the biggest mini-tablets (d = 3.0 mm), with an RSD no larger than 5.0%. Additionally, coating thickness was evaluated by colorimetric analysis (n = 1000), using a scanner method, and expressed as a hue value. A high correlation (R = 0.993) between inter-tablet variability of hue and UV-Vis results was obtained. Mini-tablets were successfully coated in a fluid bed system using both a classical Wurster distributor as well as a swirl generator. However, regardless of the mini-tablets’ diameter, better film uniformity was achieved in the case of a distributor with a swirl generator.


2021 ◽  
pp. 101900
Author(s):  
Rafael Quelho de Macedo ◽  
Rafael Thiago Luiz Ferreira ◽  
Andrew Gleadall ◽  
Ian Ashcroft

Designs ◽  
2020 ◽  
Vol 4 (3) ◽  
pp. 19
Author(s):  
Andreas K. Lianos ◽  
Harry Bikas ◽  
Panagiotis Stavropoulos

The design methodologies and part shape algorithms for additive manufacturing (AM) are rapidly growing fields, proven to be of critical importance for the uptake of additive manufacturing of parts with enhanced performance in all major industrial sectors. The current trend for part design is a computationally driven approach where the parts are algorithmically morphed to meet the functional requirements with optimized performance in terms of material distribution. However, the manufacturability restrictions of AM processes are not considered at the primary design phases but at a later post-morphed stage of the part’s design. This paper proposes an AM design method to ensure: (1) optimized material distribution based on the load case and (2) the part’s manufacturability. The buildability restrictions from the direct energy deposition (DED) AM technology were used as input to the AM shaping algorithm to grant high AM manufacturability. The first step of this work was to define the term of AM manufacturability, its effect on AM production, and to propose a framework to estimate the quantified value of AM manufacturability for the given part design. Moreover, an AM design method is proposed, based on the developed internal stresses of the build volume for the load case. Stress tensors are used for the determination of the build orientation and as input for the part morphing. A top-down mesoscale geometric optimization is used to realize the AM part design. The DED Design for Additive Manufacturing (DfAM) rules are used to delimitate the morphing of the part, representing at the same time the freeform mindset of the AM technology. The morphed shape of the part is optimized in terms of topology and AM manufacturability. The topology optimization and AM manufacturability indicator (TMI) is introduced to screen the percentage of design elements that serve topology optimization and the ones that serve AM manufacturability. In the end, a case study for proof of concept is realized.


2019 ◽  
Vol 11 (9) ◽  
pp. 2571
Author(s):  
Xujing Zhang ◽  
Lichuan Wang ◽  
Yan Chen

Low-carbon production has become one of the top management objectives for every industry. In garment manufacturing, the material distribution process always generates high carbon emissions. In order to reduce carbon emissions and the number of operators to meet enterprises’ requirements to control the cost of production and protect the environment, the paths of material distribution were analyzed to find the optimal solution. In this paper, the model of material distribution to obtain minimum carbon emissions and vehicles (operators) was established to optimize the multi-target management in three different production lines (multi-line, U-shape two-line, and U-shape three-line), while the workstations were organized in three ways: in the order of processes, in the type of machines, and in the components of garment. The NSGA-II algorithm (non-dominated sorting genetic algorithm-II) was applied to obtain the results of this model. The feasibility of the model and algorithm was verified by the practice of men’s shirts manufacture. It could be found that material distribution of multi-line layout produced the least carbon emissions when the machines were arranged in the group of type.


1967 ◽  
Vol 45 (12) ◽  
pp. 2267-2327 ◽  
Author(s):  
J. A. Parmelee

Sixty-two taxa are recognized in this study of the species of Puccinia completing their life cycle on Heliantheae. Six new species are described: Puccinia guatemalensis Parmelee on Zexmenia spp. and Wedelia spp., P. ghiesbreghtii Parmelee on Wedelia ghiesbreghtii, P. abramsii Parmelee on Geraea viscida (= Encelia viscida), P. chloracae Parmelee on Viguiera spp., P. calanticariae Parmelee on Viguiera spp., and P. praetermissa Parmelee on Lagascea spp. Six new varieties are recognized: Puccinia electrae var. robusta Parmelee and P. electrae var. depressiporosa Parmelee on Zexmenia brevifolia, P. caleae var. cuernavacae Parmelee on Calea spp., P. cognata var. echinulata Parmelee on Verbesina spp., P. cognata var. fraseri Parmelee on Viguiera fraseri, and P. affinis var. triporosa Parmelee on Viguiera spp. Three taxa have been restored from synonomy under P. abrupta, viz. P. subglobosa, P. ximenesiae, and P. affinis, the last two parasitic on Verbesina spp., the first on Rhysolepis (= Viguiera). P. tithoniae, P. nanomitra, and P. ordinata, are reduced to synonomy with P. enceliae var. enceliae, P. iostephanes, and P. melampodii respectively. New combinations include: P. enceliae var. aemulans (Syd.) Parmelee and P. abrupta var. partheniicola (Jacks.) Parmelee. A key based on uredinial and telial characters, others based initially on the hosts, and a host index are provided. Each taxon is illustrated by a photomicrograph from type material. Distribution and host extensions, supplementary to those given in Arthur's Manual of the Rusts, are indicated.


Author(s):  
Daniel Halliday ◽  
Miranda Stewart

This chapter investigates whether the replication of inequality is, other things being equal, morally objectionable in ways not applicable to inequality that remains confined to a single generation or “birth cohort.” The focus is both theoretical and practical. The chapter considers the philosophical foundations that might lie behind an objection to dynastic inequality, negotiating the diversity of egalitarian views supporting this position and the complexity around the causal mechanisms at work in cases where inequality has a dynastic tendency. It then discusses the policy reforms that might target inequalities that replicate old distributive trends while leaving newly produced trends more intact, with a focus on tax policy. Current tax rules in most developed economies do not make a distinction between new and old influences on the material distribution. Accordingly, it is likely that the tax reforms implied could be quite extensive.


2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Aayush Bhat ◽  
Vyom Gupta ◽  
Savitoj Singh Aulakh ◽  
Renold S. Elsen

Purpose The purpose of this paper is to implement the generative design as an optimization technique to achieve a reasonable trade-off between weight and reliability for the control arm plate of a double-wishbone suspension assembly of a Formula Student race car. Design/methodology/approach The generative design methodology is applied to develop a low-weight design alternative to a standard control arm plate design. A static stress simulation and a fatigue life study are developed to assess the response of the plate against the loading criteria and to ensure that the plate sustains the theoretically determined number of loading cycles. Findings The approach implemented provides a justifiable outcome for a weight-factor of safety trade-off. In addition to optimal material distribution, the generative design methodology provides several design outcomes, for different materials and fabrication techniques. This enables the selection of the best possible outcome for several structural requirements. Research limitations/implications This technique can be used for applications with pre-defined constraints, such as packaging and loading, usually observed in load-bearing components developed in the automotive and aerospace sectors of the manufacturing industry. Practical implications Using this technique can provide an alternative design solution to long periods spent in the design phase, because of its ability to generate several possible outcomes in just a fraction of time. Originality/value The proposed research provides a means of developing optimized designs and provides techniques in which the design developed and chosen can be structurally analyzed.


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