High precision FPGA real-time linear structured light imaging system

2021 ◽  
Author(s):  
Lin Gu ◽  
Zhongwen Fei ◽  
Wen Wang ◽  
Jialin Wu ◽  
Xiaobin Xu
Keyword(s):  
Real Time ◽  
High Precision ◽  
Imaging System ◽  
Structured Light ◽  
Time Linear

scholarly journals Three-Dimensional Microscopic Image Reconstruction Based on Structured Light Illumination

Sensors ◽  
2021 ◽  
Vol 21 (18) ◽  
pp. 6097
Author(s):  
Taichu Shi ◽  
Yang Qi ◽  
Cheng Zhu ◽  
Ying Tang ◽  
Ben Wu
Keyword(s):  
Real Time ◽  
Imaging System ◽  
Structured Light ◽  
Three Dimensional ◽  
Light Illumination ◽  
3D Image ◽  
Light Pattern ◽  
Structured Light Illumination ◽  
Working Distance ◽  
3D Information

In this paper, we propose and experimentally demonstrate a three-dimensional (3D) microscopic system that reconstructs a 3D image based on structured light illumination. The spatial pattern of the structured light changes according to the profile of the object, and by measuring the change, a 3D image of the object is reconstructed. The structured light is generated with a digital micro-mirror device (DMD), which controls the structured light pattern to change in a kHz rate and enables the system to record the 3D information in real time. The working distance of the imaging system is 9 cm at a resolution of 20 μm. The resolution, working distance, and real-time 3D imaging enable the system to be applied in bridge and road crack examinations, and structure fault detection of transportation infrastructures.

scholarly journals Fast High-Precision Electrical Impedance Tomography System for Real-Time Perfusion Imaging

IEEE Access ◽  
2019 ◽  
Vol 7 ◽  
pp. 61570-61580 ◽  
Author(s):  
Weichen Li ◽  
Junying Xia ◽  
Ge Zhang ◽  
Hang Ma ◽  
Benyuan Liu ◽  
...  
Keyword(s):  
Real Time ◽  
Electrical Impedance Tomography ◽  
High Precision ◽  
Perfusion Imaging ◽  
Electrical Impedance ◽  
Impedance Tomography ◽  
Tomography System

scholarly journals A High-Precision Registration Technology Based on Bundle Adjustment in Structured Light Scanning System

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Jianying Yuan ◽  
Qiong Wang ◽  
Xiaoliang Jiang ◽  
Bailin Li
Keyword(s):  
High Precision ◽  
Large Scale ◽  
Structured Light ◽  
Bundle Adjustment ◽  
Scanning System ◽  
Control Points ◽  
Registration Method ◽  
Global Control ◽  
3D Data ◽  
Structured Light Scanning

The multiview 3D data registration precision will decrease with the increasing number of registrations when measuring a large scale object using structured light scanning. In this paper, we propose a high-precision registration method based on multiple view geometry theory in order to solve this problem. First, a multiview network is constructed during the scanning process. The bundle adjustment method from digital close range photogrammetry is used to optimize the multiview network to obtain high-precision global control points. After that, the 3D data under each local coordinate of each scan are registered with the global control points. The method overcomes the error accumulation in the traditional registration process and reduces the time consumption of the following 3D data global optimization. The multiview 3D scan registration precision and efficiency are increased. Experiments verify the effectiveness of the proposed algorithm.

scholarly journals High-precision and cost-efficient sequencing for real-time COVID-19 surveillance

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Sung Yong Park ◽  
Gina Faraci ◽  
Pamela M. Ward ◽  
Jane F. Emerson ◽  
Ha Youn Lee
Keyword(s):  
Los Angeles ◽  
Whole Genome Sequencing ◽  
Real Time ◽  
Genome Sequencing ◽  
High Precision ◽  
High Throughput Sequencing ◽  
Whole Genome ◽  
Sequencing Data ◽  
Public Health Response ◽  
Cost Efficient

AbstractCOVID-19 global cases have climbed to more than 33 million, with over a million total deaths, as of September, 2020. Real-time massive SARS-CoV-2 whole genome sequencing is key to tracking chains of transmission and estimating the origin of disease outbreaks. Yet no methods have simultaneously achieved high precision, simple workflow, and low cost. We developed a high-precision, cost-efficient SARS-CoV-2 whole genome sequencing platform for COVID-19 genomic surveillance, CorvGenSurv (Coronavirus Genomic Surveillance). CorvGenSurv directly amplified viral RNA from COVID-19 patients’ Nasopharyngeal/Oropharyngeal (NP/OP) swab specimens and sequenced the SARS-CoV-2 whole genome in three segments by long-read, high-throughput sequencing. Sequencing of the whole genome in three segments significantly reduced sequencing data waste, thereby preventing dropouts in genome coverage. We validated the precision of our pipeline by both control genomic RNA sequencing and Sanger sequencing. We produced near full-length whole genome sequences from individuals who were COVID-19 test positive during April to June 2020 in Los Angeles County, California, USA. These sequences were highly diverse in the G clade with nine novel amino acid mutations including NSP12-M755I and ORF8-V117F. With its readily adaptable design, CorvGenSurv grants wide access to genomic surveillance, permitting immediate public health response to sudden threats.

scholarly journals Performance of a novel protease-activated fluorescent imaging system for intraoperative detection of residual breast cancer during breast conserving surgery

2021 ◽  
Vol 187 (1) ◽  
pp. 145-153
Author(s):  
Conor R. Lanahan ◽  
Bridget N. Kelly ◽  
Michele A. Gadd ◽  
Michelle C. Specht ◽  
Carson L. Brown ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Real Time ◽  
Imaging System ◽  
Ex Vivo ◽  
Menopausal Status ◽  
Fluorescent Imaging ◽  
Cancer Subtypes ◽  
Surgical Workflow ◽  
Tumor Types

Abstract Purpose Safe breast cancer lumpectomies require microscopically clear margins. Real-time margin assessment options are limited, and 20–40% of lumpectomies have positive margins requiring re-excision. The LUM Imaging System previously showed excellent sensitivity and specificity for tumor detection during lumpectomy surgery. We explored its impact on surgical workflow and performance across patient and tumor types. Methods We performed IRB-approved, prospective, non-randomized studies in breast cancer lumpectomy procedures. The LUM Imaging System uses LUM015, a protease-activated fluorescent imaging agent that identifies residual tumor in the surgical cavity walls. Fluorescent cavity images were collected in real-time and analyzed using system software. Results Cavity and specimen images were obtained in 55 patients injected with LUM015 at 0.5 or 1.0 mg/kg and in 5 patients who did not receive LUM015. All tumor types were distinguished from normal tissue, with mean tumor:normal (T:N) signal ratios of 3.81–5.69. T:N ratios were 4.45 in non-dense and 4.00 in dense breasts (p = 0.59) and 3.52 in premenopausal and 4.59 in postmenopausal women (p = 0.19). Histopathology and tumor receptor testing were not affected by LUM015. Falsely positive readings were more likely when tumor was present < 2 mm from the adjacent specimen margin. LUM015 signal was stable in vivo at least 6.5 h post injection, and ex vivo at least 4 h post excision. Conclusions Intraoperative use of the LUM Imaging System detected all breast cancer subtypes with robust performance independent of menopausal status and breast density. There was no significant impact on histopathology or receptor evaluation.

scholarly journals LOCUS: A Multi-Sensor Lidar-Centric Solution for High-Precision Odometry and 3D Mapping in Real-Time

2021 ◽  
Vol 6 (2) ◽  
pp. 421-428
Author(s):  
Matteo Palieri ◽  
Benjamin Morrell ◽  
Abhishek Thakur ◽  
Kamak Ebadi ◽  
Jeremy Nash ◽  
...  
Keyword(s):  
Real Time ◽  
High Precision ◽  
3D Mapping
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