A compact, in-line diffraction system to detect counterfeit pharmaceuticals in their packaging

2021 ◽  
Author(s):  
Joachim Tabary ◽  
Marie-Claude Gentet ◽  
Olivier Monnet ◽  
Christophe Greffe ◽  
Damien Koch ◽  
...  
Keyword(s):  
Counterfeit Pharmaceuticals

WHO: Counterfeit pharmaceuticals

The Lancet ◽  
1992 ◽  
Vol 339 (8799) ◽  
pp. 982 ◽  
Author(s):  
Alan McGregor
Keyword(s):  
Counterfeit Pharmaceuticals

scholarly journals Proof-of-Concept of Detection of Counterfeit Medicine through Polymeric Materials Analysis of Plastics Packaging

Polymers ◽  
2021 ◽  
Vol 13 (13) ◽  
pp. 2185
Author(s):  
Mohammad Salim ◽  
Riyanto Teguh Widodo ◽  
Mohamed Ibrahim Noordin
Keyword(s):  
Polymeric Materials ◽  
Proof Of Concept ◽  
Scanning Calorimetry ◽  
Counterfeit Drug ◽  
Drug Products ◽  
Counterfeit Medicines ◽  
Counterfeit Medicine ◽  
Counterfeit Pharmaceuticals ◽  
Purge Gas ◽  
Sample Set

The detection of counterfeit pharmaceuticals is always a major challenge, but the early detection of counterfeit medicine in a country will reduce the fatal risk among consumers. Technically, fast laboratory testing is vital to develop an effective surveillance and monitoring system of counterfeit medicines. This study proposed the combination of Attenuated Total Reflectance Fourier Transform Infrared (ATR-FTIR) and Differential Scanning Calorimetry (DSC) for the quick detection of counterfeit medicines, through the polymer analysis of blister packaging materials. A sample set containing three sets of original and counterfeit medicine was analyzed using ATR-FTIR and DSC, while the spectra from ATR-FTIR were employed as a fingerprint for the polymer characterization. Intending to analyze the polymeric material of each sample, DSC was set at a heating rate of 10 °C min−l and within a temperature range of 0- 400 °C, with nitrogen as a purge gas at a flow rate of 20 ml min−an. The ATR-FTIR spectra revealed the chemical characteristics of the plastic packaging of fake and original medicines. Further analysis of the counterfeit medicine’s packaging with DSC exhibited a distinct difference from the original due to the composition of polymers in the packaging material used. Overall, this study confirmed that the rapid analysis of polymeric materials through ATR-FTIR and comparing DSC thermograms of the plastic in their packaging effectively distinguished counterfeit drug products.

Fake Pharmaceuticals: How They and Relevant Legislation or Lack Thereof Contribute to Consistently High and Increasing Drug Prices

2003 ◽  
Vol 29 (4) ◽  
pp. 525-542
Author(s):  
Merri C. Moken
Keyword(s):  
United States ◽  
Prescription Drugs ◽  
The United States ◽  
Pharmaceutical Products ◽  
New Drugs ◽  
Pharmaceutical Companies ◽  
Brand Name ◽  
Potential Factors ◽  
Counterfeit Pharmaceuticals ◽  
New Applications

The use of pharmaceutical products in the United States has increased more than the use of any other health resource from 1960 to 1990. In excess of 9,600 drugs were on the market in 1984, and the Food and Drug Administration (“FDA”) approves approximately 30 new drugs and countless new applications for alterations of already existing drugs each year. In 2001, the $300 billion pharmaceutical industry sold $154 billion worth of prescription drugs in the United States alone, nearly doubling its $78.9 billion in sales in 1997. With such a rapid increase in market domination and expenditures, the U.S. government and many hospitals have focused their attention on the sales and pricing practices of pharmaceutical companies, as well as other potential factors contributing to these escalating prices. One such cause of the steadily increasing prices of brand name pharmaceuticals is the sale of fake or counterfeit pharmaceuticals (also called “look-alike” drugs).

National security: health care, pandemic (COVID-19) and the global trade in counterfeit pharmaceuticals (part 2)

2021 ◽  
pp. 52-62
Author(s):  
H. O. Androshchuk
Keyword(s):  
Intellectual Property ◽  
National Security ◽  
Poverty Line ◽  
Third Wave ◽  
Legal Analysis ◽  
Management Measures ◽  
Timely Response ◽  
Counterfeit Pharmaceuticals ◽  
The Impact ◽  
The Eu

Ukraine’s healthcare system faces unprecedented national security challenges in the third wave of the COVID-19 pandemic. A particularly acute issue is countering counterfeit pharmaceuticals, preventing drug shortages, joining efforts of the authorities and national manufacturers of drugs and medical supplies. According to the UN, more than 60 % of the population lives below the poverty line in Ukraine. Timely response to these challenges and taking preventive measures will save lives, minimize the volume and consequences of the pandemic. The paper provides an economic and legal analysis, trends, risks and threats to national security of the state and health protection during a pandemic, in order to protect intellectual property rights, adequate coordination of actions at the national and international levels. The impact of counterfeiting on the criminal landscape in the EU, and also business and economy, is shown based on the analysis of studies by the OECD, the EU Intellectual Property Office (EUIPO) and Europol. The foundations of anti-counterfeiting management, measures to implement a standard anti-counterfeiting strategy are proposed.

National security: health care, pandemic (COVID-­19) and the global trade in counterfeit pharmaceuticals (Part 1)

2021 ◽  
pp. 52-61
Author(s):  
H. O. Androshchuk
Keyword(s):  
Intellectual Property ◽  
National Security ◽  
Poverty Line ◽  
Third Wave ◽  
Legal Analysis ◽  
Management Measures ◽  
Timely Response ◽  
Counterfeit Pharmaceuticals ◽  
The Impact ◽  
The Eu

Ukraine’s healthcare system faces unprecedented national security challenges in the third wave of the COVID-19 pandemic. A particularly acute issue is countering counterfeit pharmaceuticals, preventing drug shortages, joining efforts of the authorities and national manufacturers of drugs and medicines. According to the UN in Ukraine more than 60% of the population lives below the poverty line. Timely response to these challenges and taking preventive measures will save lives, minimize the volume and consequences of the pandemic. The work provides an economic and legal analysis, trends, risks and threats to the national security of the state and health protection during a pandemic, in order to protect intellectual property rights, adequate coordination of actions at the national and international levels. Based on the analysis of studies by the OECD, the EU Intellectual Property Office (EUIPO) and Europol shows the impact of counterfeiting on business and the economy, the criminal landscape in the EU. The basics of the anti-counterfeiting management, measures to implement a standard anti-counterfeiting strategy are proposed.

scholarly journals Detecting Counterfeit Pharmaceuticals through UV Spectrophotometry

2016 ◽  
Vol 110 (3) ◽  
pp. 490a
Author(s):  
Gabriela Figueroa ◽  
Bruce Ray ◽  
Horia Petrache
Keyword(s):  
Uv Spectrophotometry ◽  
Counterfeit Pharmaceuticals

Counterfeit Pharmaceuticals: Current Status and Future Projections

2003 ◽  
Vol 43 (6) ◽  
pp. 710-718 ◽  
Author(s):  
Albert I. Wertheimer ◽  
Nicole M. Chaney ◽  
Thomas Santella
Keyword(s):  
Current Status ◽  
Future Projections ◽  
Counterfeit Pharmaceuticals

Health Risks of Counterfeit Pharmaceuticals

Drug Safety ◽  
2003 ◽  
Vol 26 (14) ◽  
pp. 991-997 ◽  
Author(s):  
Martijn ten Ham
Keyword(s):  
Health Risks ◽  
Counterfeit Pharmaceuticals
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