Indocyanine-green matching phantom for fluorescence-guided imaging systems: Updates, photostability, and a fully 3D-printed design

2021 ◽  
Author(s):  
Alberto J. Ruiz ◽  
Ethan P. M. LaRochelle ◽  
Brian W. Pogue
Keyword(s):  
Indocyanine Green ◽  
Imaging Systems ◽  
3D Printed

3D printed biomimetic vascular phantoms for assessment of hyperspectral imaging systems

2015 ◽  
Author(s):  
Jianting Wang ◽  
Pejhman Ghassemi ◽  
Anthony Melchiorri ◽  
Jessica Ramella-Roman ◽  
Scott A. Mathews ◽  
...  
Keyword(s):  
Hyperspectral Imaging ◽  
Imaging Systems ◽  
3D Printed

scholarly journals Democratising “Microscopi”: a 3D printed automated XYZT fluorescence imaging system for teaching, outreach and fieldwork

2021 ◽  
Vol 6 ◽  
pp. 63
Author(s):  
Matthew Wincott ◽  
Andrew Jefferson ◽  
Ian M. Dobbie ◽  
Martin J. Booth ◽  
Ilan Davis ◽  
...  
Keyword(s):  
Fluorescence Imaging ◽  
Imaging System ◽  
Imaging Systems ◽  
Image Capture ◽  
Optical Components ◽  
Web Based ◽  
Automated Imaging ◽  
Fluorescence Imaging System ◽  
3D Printed ◽  
Imaging Performance

Commercial fluorescence microscope stands and fully automated XYZt fluorescence imaging systems are generally beyond the limited budgets available for teaching and outreach. We have addressed this problem by developing “Microscopi”, an accessible, affordable, DIY automated imaging system that is built from 3D printed and commodity off-the-shelf hardware, including electro-mechanical, computer and optical components. Our design features automated sample navigation and image capture with a simple web-based graphical user interface, accessible with a tablet or other mobile device. The light path can easily be switched between different imaging modalities. The open source Python-based control software allows the hardware to be driven as an integrated imaging system. Furthermore, the microscope is fully customisable, which also enhances its value as a learning tool. Here, we describe the basic design and demonstrate imaging performance for a range of easily sourced specimens.

3D MICROSENSOR IMAGING ARRAYS NETWORKS

2015 ◽  
Vol 2015 (DPC) ◽  
pp. 000348-000378
Author(s):  
David Fries ◽  
Geran Barton
Keyword(s):  
3D Printing ◽  
Flexible Electronics ◽  
Mobile Robotics ◽  
Imaging Systems ◽  
Flow Imaging ◽  
Large Area ◽  
Camera Systems ◽  
3D Printed ◽  
Third Dimension ◽  
Microsensor Arrays

2D microsensor arrays can permit spatial distribution measurements of the sensed parameter and enable high resolution sensing visualizations. Measuring constituents in a flowing media, such as air or liquid could benefit from such flow through or flow across imaging systems. These flow imagers can have applications in mobile robotics and non-visible imagery, and alternate mechanical systems of perception, process control and environmental observations. In order to create rigid-conformal, large area imaging systems we have in the past merged flexible PCB substrates with rigid constructions from 3D printing. This approach merges the 2D flexible electronics world of printed circuits with the 3D printed packaging world. Extending this 2D flow imaging concept into the third dimension permits 3D flow imaging networks, architectures and designs and can create a new class of sensing systems. Using 3D printing, 3D printed filaments, nets and microsensor cages, can be combined into integrated designs to generate distributed 3D imaging networks and camera systems for a variety of sensory applications.

Digital imaging and quantitative image analysis of polymer blends

1996 ◽  
Vol 54 ◽  
pp. 170-171
Author(s):  
Xiao Zhang
Keyword(s):  
Digital Imaging ◽  
Imaging Techniques ◽  
Imaging Systems ◽  
Polymer Science ◽  
Key Factors ◽  
Multiple Imaging ◽  
Quantitative Image ◽  
Digital Imaging Systems ◽  
Multi Phase ◽  
Network Technologies

Polymer microscopy involves multiple imaging techniques. Speed, simplicity, and productivity are key factors in running an industrial polymer microscopy lab. In polymer science, the morphology of a multi-phase blend is often the link between process and properties. The extent to which the researcher can quantify the morphology determines the strength of the link. To aid the polymer microscopist in these tasks, digital imaging systems are becoming more prevalent. Advances in computers, digital imaging hardware and software, and network technologies have made it possible to implement digital imaging systems in industrial microscopy labs.

Enhanced type I photoreaction of indocyanine green via electrostatic-force-driven aggregation

Nanoscale ◽  
2020 ◽  
Vol 12 (17) ◽  
pp. 9517-9523 ◽  
Author(s):  
Huizhen Fan ◽  
Yu Fan ◽  
Wenna Du ◽  
Rui Cai ◽  
Xinshuang Gao ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Indocyanine Green ◽  
Electrostatic Force ◽  
Type I ◽  
Positively Charged

ICG forms aggregates in positively charged mesoporous silica, which show an enhanced type I photoreaction pathway.

Initial experience with a new quantitative assessment tool for fluorescent imaging in peripheral artery disease

VASA ◽  
2017 ◽  
Vol 46 (5) ◽  
pp. 383-388 ◽  
Author(s):  
Henrik Christian Rieß ◽  
Anna Duprée ◽  
Christian-Alexander Behrendt ◽  
Tilo Kölbel ◽  
Eike Sebastian Debus ◽  
...  
Keyword(s):  
Indocyanine Green ◽  
Quantitative Assessment ◽  
Tissue Perfusion ◽  
Fluorescent Imaging ◽  
Peripheral Artery ◽  
Peripheral Bypass ◽  
Before And After ◽  
Artery Disease ◽  
Green Fluorescent ◽  
Peripheral Bypass Grafting

Abstract. Background: Perioperative evaluation in peripheral artery disease (PAD) by common vascular diagnostic tools is limited by open wounds, medial calcinosis or an altered collateral supply of the foot. Indocyanine green fluorescent imaging (ICG-FI) has recently been introduced as an alternative tool, but so far a standardized quantitative assessment of tissue perfusion in vascular surgery has not been performed for this purpose. The aim of this feasibility study was to investigate a new software for quantitative assessment of tissue perfusion in patients with PAD using indocyanine green fluorescent imaging (ICG-FI) before and after peripheral bypass grafting. Patients and methods: Indocyanine green fluorescent imaging was performed in seven patients using the SPY Elite system before and after peripheral bypass grafting for PAD (Rutherford III-VI). Visual and quantitative evaluation of tissue perfusion was assessed in an area of low perfusion (ALP) and high perfusion (AHP), each by three independent investigators. Data assessment was performed offline using a specially customized software package (Institute for Laser Technology, University Ulm, GmbH). Slope of fluorescent intensity (SFI) was measured as time-intensity curves. Values were compared to ankle-brachial index (ABI), slope of oscillation (SOO), and time to peak (TTP) obtained from photoplethysmography (PPG). Results: All measurements before and after surgery were successfully performed, showing that ABI, TTP, and SOO increased significantly compared to preoperative values, all being statistically significant (P < 0.05), except for TTP (p = 0.061). Further, SFI increased significantly in both ALP and AHP (P < 0.05) and correlated considerably with ABI, TTP, and SOO (P < 0.05). Conclusions: In addition to ABI and slope of oscillation (SOO), the ICG-FI technique allows visual assessment in combination with quantitative assessment of tissue perfusion in patients with PAD. Ratios related to different perfusion patterns and SFI seem to be useful tools to reduce factors disturbing ICG-FI measurements.

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