Strategies of improving lesion detection in wide-angle digital breast tomosynthesis (DBT) with angular dose distribution and detector design

2021 ◽  
Author(s):  
Xiaoyu Duan ◽  
Hailiang Huang ◽  
Wei Zhao
Keyword(s):  
Dose Distribution ◽  
Digital Breast Tomosynthesis ◽  
Lesion Detection ◽  
Wide Angle ◽  
Breast Tomosynthesis ◽  
Detector Design

scholarly journals Lesion Detection in Breast Tomosynthesis Using Efficient Deep Learning and Data Augmentation Techniques

2021 ◽  
Author(s):  
Loay Hassan ◽  
Mohamed Abedl-Nasser ◽  
Adel Saleh ◽  
Domenec Puig
Keyword(s):  
Breast Cancer ◽  
Deep Learning ◽  
Breast Lesion ◽  
Data Augmentation ◽  
Digital Breast Tomosynthesis ◽  
Lesion Detection ◽  
Detection Methods ◽  
Breast Tomosynthesis ◽  
Mammographic Images ◽  
Augmentation Techniques

Digital breast tomosynthesis (DBT) is one of the powerful breast cancer screening technologies. DBT can improve the ability of radiologists to detect breast cancer, especially in the case of dense breasts, where it beats mammography. Although many automated methods were proposed to detect breast lesions in mammographic images, very few methods were proposed for DBT due to the unavailability of enough annotated DBT images for training object detectors. In this paper, we present fully automated deep-learning breast lesion detection methods. Specifically, we study the effectiveness of two data augmentation techniques (channel replication and channel-concatenation) with five state-of-the-art deep learning detection models. Our preliminary results on a challenging publically available DBT dataset showed that the channel-concatenation data augmentation technique can significantly improve the breast lesion detection results for deep learning-based breast lesion detectors.

Optimal angular dose distribution to acquire 3D and extra 2D images for digital breast tomosynthesis (DBT)

2015 ◽  
Vol 67 (3) ◽  
pp. 590-598
Author(s):  
Hye-Suk Park ◽  
Ye-Seul Kim ◽  
Haeng-Hwa Lee ◽  
Won-Suk Gang ◽  
Hee-Joung Kim ◽  
...  
Keyword(s):  
Dose Distribution ◽  
Digital Breast Tomosynthesis ◽  
Breast Tomosynthesis ◽  
2D Images

Synthetic 2-Dimensional Mammography Can Replace Digital Mammography as an Adjunct to Wide-Angle Digital Breast Tomosynthesis

2019 ◽  
Vol 54 (2) ◽  
pp. 83-88 ◽  
Author(s):  
Paola Clauser ◽  
Pascal A.T. Baltzer ◽  
Panagiotis Kapetas ◽  
Ramona Woitek ◽  
Michael Weber ◽  
...  
Keyword(s):  
Digital Mammography ◽  
Digital Breast Tomosynthesis ◽  
Wide Angle ◽  
Breast Tomosynthesis

scholarly journals Detection of microcalcification clusters by 2D-mammography and narrow and wide angle digital breast tomosynthesis

2016 ◽  
Author(s):  
Andria Hadjipanteli ◽  
Premkumar Elangovan ◽  
Padraig T. Looney ◽  
Alistair Mackenzie ◽  
Kevin Wells ◽  
...  
Keyword(s):  
Digital Breast Tomosynthesis ◽  
Wide Angle ◽  
Breast Tomosynthesis ◽  
Microcalcification Clusters

scholarly journals Value of Digital Breast Tomosynthesis versus Additional Views for the Assessment of Screen-Detected Abnormalities - a First Analysis

Breast Care ◽  
2017 ◽  
Vol 12 (2) ◽  
pp. 91-96 ◽  
Author(s):  
Sylvia Heywang-Köbrunner ◽  
Alexander Jaensch ◽  
Astrid Hacker ◽  
Sabina Wulz-Horber ◽  
Thomas Mertelmeier ◽  
...  
Keyword(s):  
Digital Breast Tomosynthesis ◽  
Ethics Committee ◽  
Wide Angle ◽  
Breast Tomosynthesis ◽  
Single View ◽  
Extra Information ◽  
Standard Assessment ◽  
Sensitivity Specificity ◽  
Blinded Reader

Background: The purpose of this study was to countercheck the equivalence of single-view digital breast tomosynthesis (DBT) or DBT with additional views (DBT+AV) compared to traditional standard assessment by additional views (AV) in patients with a screen-detected abnormality. Patients and Methods: Patients with a screen-detected abnormality were consecutively invited to obtain 1 single-view wide-angle DBT in addition to the indicated AV. The study was approved by the local ethics committee and by the Federal Office for Radiation Protection. Results: This study is based on 311 lesions in 285 patients with a follow-up of > 2 years and/or biopsy. Counting BI-RADS 0 and 3 as positive calls, the sensitivity/specificity of DBT+AV versus DBT only versus AV only were 96.4/54.3%, 96.4/56.6%, and 90.9/42.2%, respectively. The specificities and BI-RADS classifications differed significantly (p < 0.01). AV appeared unnecessary in 88.8% of the cases. Conclusion: DBT appeared to be at least equivalent to AV for assessing indeterminate screen-detected lesions and could replace AV for most lesions. To obtain the extra information appears possible without increasing the overall radiation dose. Subsequent blinded reader studies are ongoing.

scholarly journals One view or two views for wide-angle tomosynthesis with synthetic mammography in the assessment setting?

2021 ◽  
Author(s):  
Paola Clauser ◽  
Pascal A. T. Baltzer ◽  
Panagiotis Kapetas ◽  
Ramona Woitek ◽  
Michael Weber ◽  
...  
Keyword(s):  
Digital Mammography ◽  
Detection Rate ◽  
Diagnostic Performance ◽  
Digital Breast Tomosynthesis ◽  
Rate Sensitivity ◽  
Breast Lesions ◽  
Wide Angle ◽  
Breast Tomosynthesis ◽  
Lesion Type ◽  
Sensitivity Specificity

Abstract Objectives To evaluate the diagnostic performance in the assessment setting of three protocols: one-view wide-angle digital breast tomosynthesis (WA-DBT) with synthetic mammography (SM), two-view WA-DBT/SM, and two-view digital mammography (DM). Methods Included in this retrospective study were patients who underwent bilateral two-view DM and WA-DBT. SM were reconstructed from the WA-DBT data. The standard of reference was histology and/or 2 years follow-up. Included were 205 women with 179 lesions (89 malignant, 90 benign). Four blinded readers randomly evaluated images to assess density, lesion type, and level of suspicion according to BI-RADS. Three protocols were evaluated: two-view DM, one-view (mediolateral oblique) WA-DBT/SM, and two-view WA-DBT/SM. Detection rate, sensitivity, specificity, and accuracy were calculated and compared using multivariate analysis. Reading time was assessed. Results The detection rate was higher with two-view WA-DBT/SM (p = 0.063). Sensitivity was higher for two-view WA-DBT/SM compared to two-view DM (p = 0.001) and one-view WA-DBT/SM (p = 0.058). No significant differences in specificity were found. Accuracy was higher with both one-view WA-DBT/SM and two-view WA-DBT/SM compared to DM (p = 0.003 and > 0.001, respectively). Accuracy did not differ between one- and two-view WA-DBT/SM. Two-view WA-DBT/SM performed better for masses and asymmetries. Reading times were significantly longer when WA-DBT was evaluated. Conclusions One-view and two-view WA-DBT/SM can achieve a higher diagnostic performance compared to two-view DM. The detection rate and sensitivity were highest with two-view WA-DBT/SM. Two-view WA-DBT/SM appears to be the most appropriate tool for the assessment of breast lesions. Key Points • Detection rate with two-view wide-angle digital breast tomosynthesis (WA-DBT) is significantly higher than with two-view digital mammography in the assessment setting. • Diagnostic accuracy of one-view and two-view WA-DBT with synthetic mammography (SM) in the assessment setting is higher than that of two-view digital mammography. • Compared to one-view WA-DBT with SM, two-view WA-DBT with SM seems to be the most appropriate tool for the assessment of breast lesions.

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